System for treating tissue swelling
First Claim
1. A therapeutic system for the treatment of tissue swelling, the system comprising:
- a) one or more recovery catheters implantable within then body and comprising semipermeable membranes, b) recovery components for recovering bulk fluid or fluid components through the semipermeable membranes and from the tissue site, in order to achieve a therapeutic result, preferably in the form of a reduction in swelling, and c) a hydratable medium comprising a hydratable gas adapted to be used directly or indirectly with the tissue site and within the semipermeable membrane(s) under conditions suitable to remove water from the tissue site in the form of hydrated medium.
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Accused Products
Abstract
A system and method for performing site specific therapy to alleviate tissue swelling, involving the placement and use of recovery catheters having semipermeable membranes adapted to recover bulk fluid or fluid components from a tissue site. Fluid recovery can be accomplished by the delivery of a hydratable medium to the membranes, under conditions suitable to permit fluid or components to pass through the membranes in order to hydrate the medium, which is then removed from the tissue site. The method and system can also include the use of components for monitoring the progress of the system, and components for introducing a recovery catheter to a tissue site.
186 Citations
28 Claims
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1. A therapeutic system for the treatment of tissue swelling, the system comprising:
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a) one or more recovery catheters implantable within then body and comprising semipermeable membranes, b) recovery components for recovering bulk fluid or fluid components through the semipermeable membranes and from the tissue site, in order to achieve a therapeutic result, preferably in the form of a reduction in swelling, and c) a hydratable medium comprising a hydratable gas adapted to be used directly or indirectly with the tissue site and within the semipermeable membrane(s) under conditions suitable to remove water from the tissue site in the form of hydrated medium. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19, 20, 21, 22, 23, 24)
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17. A therapeutic system for the treatment of tissue swelling, the system comprising:
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a) one or more recovery catheters comprising semipermeable membranes, b) introducing components adapted to position the recovery catheter(s) within a tissue site exhibiting swelling, c) recovery components for recovering bulk fluid or fluid components through the semipermeable membranes and from the tissue site, in order to achieve a reduction in swelling, d) a hydratable medium comprising a hydratable gas adapted to be delivered to the tissue site and within the semipermeable membrane(s) under conditions suitable to remove water from the tissue site in the form of hydrated medium, and e) monitoring components associated with the recovery catheter(s) and adapted to monitor one or more physiologic parameters selected from the group consisting of tissue pressure, blood flow, hydration, temperature, pH, and biochemical parameters, wherein the system is adapted for the treatment of compartment syndrome or cerebral edema, the recovery components comprise a combination of negative hydrostatic pressure and diffusion adapted to control the movement of fluid from the tissue and into the semipermeable membranes, and negative hydrostatic pressure adapted to remove fluid from within the lumen of the membranes and from the tissue site.
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25. A method of preparing a therapeutic system for the treatment of tissue swelling, the method comprising the steps of assembling a system comprising:
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a) one or more recovery catheters implantable within the body and comprising semipermeable membranes, b) recovery components for recovering bulk fluid or fluid components (e.g., water) through the semipermeable membranes and from the tissue site, in order to achieve a therapeutic result, preferably in the form of a reduction in swelling, and c) a hydratable medium comprising a hydratable gas adapted to be delivered to the tissue site and within the semipermeable membrane(s) under conditions suitable to remove water from the tissue site in the form of hydrated medium. - View Dependent Claims (26, 27, 28)
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Specification