Electrochemical sensor strip with low porosity screen

• US 6,942,769 B2
• Filed: 08/05/2003
• Issued: 09/13/2005
• Est. Priority Date: 08/05/2003
• Status: Expired due to Fees

• Current Assignee: BT Medical Corp.
• Original Assignee: BT Medical Corp.
• Inventors: Cheng, Chen-Heng, Chang, Jung-Tzu, Cheng, Jung
• Primary Examiner(s): Noguerola, Alex
• Application Number:
  US10/634,560
• Publication Number:
  US 20050029097A1
• Time in Patent Office: 770 Days
• Field of Search: 204/400, 20440301-40315, 204416-418
• US Class Current: 204/400
• CPC Class Codes: G01N 27/3272 Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels optical biosensors G01N33/52

Abstract

The electrode test strip is used with an electrochemical sensor for measuring an analyte in an aqueous sample, e.g., glucose in blood. The electrode strip includes an elongated electrode support, a first and second electrode on the support, a slotted dielectric layer, a screen and a slotted cover layer, all disposed atop each and atop the electrodes in the support. The dielectric layer and the cover layer are typically adhesively attached (the adhesive layers further define the slot). The slot is open to the terminal end of the test strip and the cover. The screen, interposed in the slot, has a porosity between 10%-40% to control analyte flow and volume in the slot and over the test area defined by electrode legs. Further refinements include utilizing a surfactant on the screen.

Claims

1. An electrode strip for use in an electrochemical sensor for measuring an analyte in an aqueous sample, comprising:

an elongated electrode support having a terminal end;

a first and a second electrode on said support for electrochemical analysis of said analyte, said first electrode having a forwardly disposed leg which is near said terminal end and second electrode having a rearwardly disposed leg which is rearwardly disposed with respect to both said terminal end and said forward leg of said first electrode;

a dielectric layer, a screen, and a cover layer, all disposed atop each other and atop said electrodes and said support;

said dielectric layer and cover layer having an open-topped slot therein, said slot being open to said terminal end and extending over at least said forwardly and rearwardly disposed electrode legs, said slot forming a vent at least over said forwardly and rearwardly disposed electrode legs; and

said screen having a porosity between 10% and 40% to control analyte flow and volume in said slot and over said forwardly and rearwardly disposed electrode legs.

2. An electrode strip as claimed in claim 1 including intermediate layers of adhesive, one adhesive layer disposed between said screen and said dielectric and another adhesive layer disposed between said screen and said cover layer, each intermediate adhesive layer having a respective slot generally coextensive with said slot in said dielectric layer and said cover layer.

3. An electrode strip as claimed in claim 1 wherein said screen carries a surfactant to enhance wetting by said analyte.

4. An electrode strip as claimed in claim 3 wherein the surfactant is one selected from the group consisting of sulphonal and sulfosuccinate.

5. An electrode strip as claimed in claim 1 where said screen is a polyester mesh screen with a mesh opening of about 15-20 microns.

6. An electrode strip as claimed in claim 1 wherein the screen is made from a material selected from the group consisting of polyester, nylon and polyproplene.

7. An electrode strip as claimed in claim 6 wherein said screen carries a surfactant to enhance wetting by said analyte and wherein the surfactant is one selected from the group consisting of sulphonal and sulfosuccinate.

8. An electrode strip as claimed in claim 1 wherein the screen has a mesh opening of about 15-20 microns and a mesh size of about 500 per square inch.

9. An electrode strip as claimed in claim 1 wherein the terminal end of said support and said slot gathers said analyte.

10. An electrode strip as claimed in claim 1 wherein said support includes a forward end section ending at said terminal end and a central section and a rearward end section;

said screen is disposed generally over said forwardly and rearwardly disposed electrodes and said forward end section of said support and is not disposed over said central section and rearward end sections of said support.