Method and system for controlling the temperature of a dispensed liquid

• US 6,945,638 B2
• Filed: 10/29/2002
• Issued: 09/20/2005
• Est. Priority Date: 10/29/2001
• Status: Expired due to Term

• Current Assignee: Massachusetts Institute of Technology, Theken Spine LLC (Orthofix Medical Inc.)
• Original Assignee: Massachusetts Institute of Technology, Therics Inc.
• Inventors: Teung, Patrick, Cima, Michael J., Pryor, Timothy J., Materna, Peter A.
• Primary Examiner(s): Feggins, K.
• Application Number:
  US10/284,425
• Publication Number:
  US 20030128267A1
• Time in Patent Office: 1,057 Days
• Field of Search: 347/74, 347/56, 347/75, 347/54, 347/81, 204/666
• US Class Current: 347/74
• CPC Class Codes: B01L 2200/147 Employing temperature sensors
• CPC Class Codes: B01L 2300/1805 Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
• CPC Class Codes: B01L 2300/1827 using resistive heater
• CPC Class Codes: B01L 2400/0439 ultrasonic vibrations, vibrating piezo elements
• CPC Class Codes: B01L 2400/0487 fluid pressure, pneumatics
• CPC Class Codes: B01L 2400/0633 with moving parts
• CPC Class Codes: B01L 3/0265 using valves to interrupt or meter fluid flow, e.g. using solenoids or metering valves
• CPC Class Codes: B01L 3/0268 using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
• CPC Class Codes: B41J 2/02 generating a continuous ink jet
• CPC Class Codes: B41J 2/04528 aiming at warming up the head
• CPC Class Codes: B41J 2/04563 detecting head temperature; Ink temperature
• CPC Class Codes: B41J 2002/022 Control methods or devices for continuous ink jet
• CPC Class Codes: B41J 29/377 Cooling or ventilating arrangements
• CPC Class Codes: G05D 23/1919 characterised by the type of controller

Abstract

A device for controlling or altering the temperature of a liquid at the point of dispensing. A temperature-altering device is thermally coupled to a dispensing device to compensate for heat dissipated into the liquid as it passes through the dispensing device during dispensing. The dispensing device may be for example, a miniature solenoid valve (microvalve), a piezoelectric printhead, or the like. According to aspects of the invention, a temperature-altering device provides or reduces heat at the point of dispensing in order to alter, control or maintain a constant temperature of the dispensed liquid. As a result, improvement is obtained in the consistency of the fluid regime of the dispensed droplet stream. The temperature-altering device may be a thermoelectric device capable of moving heat either from or to the dispensing structure, or may be a heater. This device may be used beneficially even when the dispensing is performed near room temperature and the liquid does not require heating to maintain its liquid state.

Claims

1. A system for controlling the temperature of a dispensed liquid at the point of dispensing comprising:

a dispenser wherein the dispenser is a microvalve;

a first heat sink thermally connected to the dispenser;

a dispensing structure downstream of the dispenser; and

a temperature-alter device thermally coupled to the dispensing structure wherein the temperature-altering device controls a temperature of the dispensing structure at the point of dispensing of the liquid.

2. The system of claim 1 wherein the dispenser and the dispensing structure are integral components.

3. The system of claim 1 wherein the temperature-altering device is a thermoelectric device.

4. The system of claim 3 further including a second heat sink thermally connected to the thermoelectric device.

5. The system of claim 4 wherein the second heat sink includes a temperature-controlled liquid flowing therethrough.

6. The system of claim 4 wherein the first heat sink and the second heat sink are connected.

7. The system of claim 4 wherein the thermoelectric device removes heat from the dispensing structure.

8. A system for controlling the temperature of a dispensed liquid at the point of dispensing comprising:

a dispenser;

a first heat sink thermally connected to the dispenser;

a dispensing structure downstream of the dispenser; and

a temperature-alter device thermally coupled to the dispensing structure wherein the temperature-altering device is a resistive heater and controls a temperature of the dispensing structure at the point of dispensing of the liquid.

9. A system for controlling the temperature of a dispensed liquid at the point of dispensing comprising:

a dispenser;

a first heat sink thermally connected to the dispenser;

a dispensing structure downstream of the dispenser;

a temperature-altering device thermally coupled to the dispensing structure wherein the temperature-altering device controls a temperature of the dispensing structure at the point of dispensing of the liquid; and

a sensor for measuring the temperature of the dispensing structure.

10. The system of claim 9 wherein the dispenser is a piezoelectric device.

11. The system of claim 9 wherein the sensor is selected from the group consisting of a thermocouple, a thermistor, a non-contact temperature-measuring instrument such as an infrared instrument and a resistance temperature detector.

12. The system of claim 9, further comprising a controller wherein the controller modifies a signal to the temperature-altering device according to the temperature measured by the sensor.

13. An apparatus for dispensing a liquid,

a dispenser:

a dispensing structure positioned downstream of the dispenser;

a temperature-altering device in thermal contact with the dispensing structure, wherein the temperature-altering device adjusts a temperature of the dispensing structure and maintains the dispensing structure temperature at a constant value.

14. The apparatus of claim 13 wherein the dispensing structure is integral to the dispenser.

15. The apparatus of claim 13 wherein the temperature-altering device has a temperature and the temperature-altering device temperature is time-varying.

16. The apparatus of claim 15 wherein the temperature-altering device temperature is time-varying depending on the dispensing structure temperature.

17. The apparatus of claim 13 wherein the temperature-altering device adjusts temperature by removing heat from the dispensing structure.

18. The apparatus of claim 13 wherein the temperature-altering device adjusts a temperature of the dispensing structure by supplying heat to the dispensing structure.

19. The apparatus of claim 13 wherein the temperature-altering device adjusts a temperature of the dispensing structure by removing heat from the dispensing structure as needed and supplying heat to the dispensing structure as needed.

20. The apparatus of claim 13 wherein the temperature-altering device is a thermoelectric device.

21. The apparatus of claim 20 further comprising a heat sink in thermal contact with the thermoelectric device.

22. The apparatus of claim 21 wherein the heat sink comprises a temperature-controlled flowing liquid.

23. The apparatus of claim 13 wherein the dispensing structure has an external cross-section which is essentially constant.

24. The apparatus of claim 13 wherein the dispensing structure has an external cross-section that is tapered, being smaller at its downstream end.

25. The apparatus of claim 13 wherein the dispensing structure has an internal cross-section which is essentially constant followed by an orifice.

26. The apparatus of claim 13 wherein the dispensing structure has an internal cross-section that is tapered, being smaller at its downstream end.

27. The apparatus of claim 13 wherein the dispensing structure is essentially a flat plate with an orifice through it.

28. The apparatus of claim 13 wherein the dispenser is a piezoelectric dispenser.

29. The apparatus of claim 28 wherein the piezoelectric dispenser operates by radial displacement of a cylindrically symmetric piezoelectric element having an interior region further including a conduit for containing fluid to be dispensed.

30. The apparatus of claim 28 wherein the piezoelectric dispenser operates by displacement of liquid due to bending of the piezoelectric element.

31. The apparatus of claim 13, further including a liquid dispensed through the dispenser, wherein the liquid comprises solid particles in the form of a suspension or slurry, and wherein the liquid may further include steric hindrants or suspending agents.

32. The apparatus of claim 13, further including a liquid dispensed through the dispenser, wherein the liquid comprises dissolved substances.

33. The apparatus of claim 13, further including a liquid dispensed through the dispenser, the liquid comprises dissolved substances or solid particles or both, and the dissolved substances or solid particles or both comprise one or more Active Pharmaceutical Ingredients.

34. The apparatus of claim 13 wherein the liquid is a liquid at 25 C.

35. The apparatus of claim 13, further including a liquid heated to above 25 C dispensed through the dispenser.

36. The apparatus of claim 13 further including a three-dimensional printing machine.

37. The apparatus of claim 13 further including a printer.

38. An apparatus for dispensing a liquid, comprising

a dispenser;

a dispensing structure positioned downstream of the dispenser;

a temperature-altering device in thermal contact with the dispensing structure, wherein the temperature-altering device adjusts a temperature of the dispensing structure and

a sensor which senses the dispensing structure temperature.

39. The apparatus of claim 38 wherein the sensor is selected from the group consisting of a thermocouple, a thermistor, a non-contact temperature-measuring instrument such as an infrared instrument, and a resistance temperature detector.

40. The apparatus of claim 38, further comprising a controller connected to the dispensing structure temperature sensor to modify a signal to the temperature-altering device.

41. The apparatus of claim 40 wherein the controller controls the dispensing structure temperature to within a range of +/−

1 degrees Celsius.

42. The apparatus of claim 41 wherein the controller controls the dispensing structure temperature to within a range of +/−

0.1 degrees Celsius.

43. An apparatus for dispensing a liquid, comprising

a dispenser;

a dispensing structure positioned downstream of the dispenser;

a temperature-altering device in thermal contact with the dispensing structure, wherein the temperature-altering device is an electrical resistive heater and adjusts a temperature of the dispensing structure.

44. The apparatus of claim 43 wherein a temperature of the electrical resistive heater is sensed by measuring its resistance.

45. An apparatus for dispensing a liquid, comprising

a dispenser wherein the dispenser is a microvalve;

a dispensing structure positioned downstream of the dispenser; and

a temperature-altering device in thermal contact with the dispensing structure, wherein the temperature-altering device adjusts a temperature of the dispensing structure.

46. The apparatus of claim 45 wherein the microvalve comprises interior regions which are filled with thermally conducting material.

47. The apparatus of claim 45 further comprising a heat sink in thermal contact with the microvalve.

48. The apparatus of claim 45 wherein the microvalve has a microvalve temperature, and further comprising a microvalve temperature control system suitable to control the microvalve temperature.

49. A printhead comprising:

an orifice suitable for issuing a continuous stream of liquid wherein the orifice has an orifice temperature;

a temperature-altering device in thermal contact with the orifice;

an electrostatic charging cell;

deflection plates; and

a sensor for measuring the orifice temperature.

50. Apparatus for dispensing a liquid, comprising

a dispenser;

and

a dispensing structure positioned downstream of the dispenser, the dispensing structure further including an electrical resistance of the dispensing structure that generates heat upon passage of a current through the dispensing structure wherein the electrical resistance of the dispensing structure is measured to indicate a temperature of the dispensing structure, and wherein heat is generated during dispensing so as to maintain a predetermined liquid temperature.

51. Apparatus for dispensing a liquid, comprising

a dispenser;

a nozzle positioned downstream of the dispenser; and

a heat sink in thermal contact with the nozzle wherein the heat sink includes a flowing liquid having a liquid temperature, wherein the liquid temperature is maintained at a desired value.

52. A method of dispensing liquid, comprising:

dispensing liquid from an apparatus having a dispenser and a dispensing structure downstream of the dispenser; and

altering a temperature of the dispensing structure wherein altering the dispensing structure temperature comprises removing heat from the dispensing structure.

53. The method of claim 52 wherein altering the dispensing structure temperature further comprises supplying heat to the dispensing structure.

54. The method of claim 53 wherein altering the dispensing structure temperature is performed by a heater.

55. The method of claim 52 wherein altering the dispensing structure temperature is performed by a thermolectic device.

56. The method of claim 53 wherein altering the dispensing structure temperature is performed by a thermoelectric device.