Drug delivery system with profiles

• US 6,945,954 B2
• Filed: 01/22/2001
• Issued: 09/20/2005
• Est. Priority Date: 04/10/1998
• Status: Expired due to Term

• Current Assignee: Milestone Scientific Incorporated
• Original Assignee: Milestone Scientific Incorporated
• Inventors: Brown, Lawrence, Hochman, Mark, Hochman, Claudia, Lockwood, Michelle, Ascione, Angelo, Johnson, Hardie
• Primary Examiner(s): Thanh, LoAn H.
• Application Number:
  US09/767,027
• Publication Number:
  US 20030078534A1
• Time in Patent Office: 1,702 Days
• Field of Search: 604 65- 67, 604151-152, 604/154, 604/156, 128/DIG.12, 128/DIG.13
• US Class Current: 604/67
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: A61M 5/16854 by monitoring line pressure
• CPC Class Codes: Y10S 128/12 Pressure infusion

Abstract

An automatic injection device includes a drive mechanism and a sensor used to determine an internal characteristic such as a force or internal pressure generated during an injection process. This characteristic is then used as a control parameter by a microprocessor or controller which generates corresponding commands to the drive mechanism. In a particularly advantageous embodiment, the characteristic is used to calculate an exit pressure at which fluid ejected by the device through an elongated tube. The drive mechanism is then operated in such a manner that the exit pressure is maintained at a predetermined level to insure that a patient does not suffer pain and/or tissue damage.

Claims

1. An electronic device for selectively injecting or withdrawing fluid from a patient'"'"'s body comprising:

a reservoir for injecting or collecting said fluid;

a fluid delivery system having a first end coupled to said reservoir and a second end adapted to be inserted into the patient'"'"'s body;

an electrical drive mechanism arranged and constructed to apply a force within said reservoir in response to commands in one of a first direction in which fluid is injected from said reservoir through said fluid delivery system into the patient and a second direction in which fluid is withdrawn from patient through said fluid delivery system;

a sensor coupled to one of said reservoir, fluid delivery system and electrical drive mechanism for sensing an internal parameter indicative of a force generated by said drive mechanism and internal resistances within said reservoir and said fluid delivery system to said force;

a controller coupled to said sensor and said electrical drive mechanism and generating commands for said electrical drive mechanism in accordance with a profile defining operational parameters including a flow rate for said drive mechanism and a peak pressure;

said controller including a calculating an entry/exit pressure at said second end as a function of said internal parameter, said controller generating further commands to said electrical drive mechanism to control said entry/exit pressure;

a memory holding a plurality of profiles, each profile defining a surgical procedure; and

a profile selector for selecting one of said profiles for said controller.

2. The device of claim 1 wherein said delivery unit has physical characteristics defining fluid flow, and wherein said memory is used to store said physical characteristic characteristics.

3. The device of claim 2 further comprising a characteristic sensor adapted to sense one of said characteristics.

4. The device of claim 2 wherein said selector is adapted to select one of said physical characteristics.

5. The device of claim 1 wherein said profiles define a fluid characteristic of said fluid.

6. The device of claim 5 wherein said fluid characteristic is selected from a fluid viscosity, fluid specific weight and fluid temperature.

7. An injection device for injection of fluids into body tissues comprising:

a fluid reservoir holding a fluid to be injected;

a fluid delivery section having a first end coupled to said fluid reseNoir and a second end adapted to be inserted into the body tissues;

a drive mechanism adapted to generate an internal pressure within said fluid reservoir in response to commands to force said fluid to flow through said fluid delivery section and out through said second end, said fluid having an exit pressure at said second end;

an input element for inputting physical characteristics of at least one of said fluid, said fluid reservoir and said fluid delivery section;

a sensor that senses an internal parameter indicative of said internal pressure;

a controller receiving said physical characteristics and said internal parameter and including a calculator for calculating an entry/exit pressure at said second end as a function of said internal parameter, said controller generating said commands to control said entry/exit pressure, said controller generating said commands in accordance with a profile;

a memory storing a plurality of profiles, each profile being associated with a particular surgical procedure and defining a plurality of operational parameters including a fluid flow rate; and

a selector for selecting one of said profiles for said controller.

8. The automatic injection device of claim 7 wherein said preselected profile defines a time dependent sequence of operation during which fluid flows from said syringe at predetermined rates.

9. The automatic injection device of claim 8 further comprising a pressure sensor adapted to measure a fluid pressure associated with the fluid from said syringe, and wherein said controller is adapted to control the fluid flow in accordance with said fluid pressure.

10. The automatic injection device of claim 9 wherein said profile includes a fluid pressure limit and wherein said controller is adapted to limit said fluid rate in accordance with said fluid pressure limit.

11. The automatic injection device of claim 7 further comprising a needle shaped to be inserted in tissues and a tube coupling said syringe to said needle.

12. The automatic injection device of claim 11 wherein said needle is defined by a needle size, wherein said memory includes a plurality of needle sizes, and wherein said selector is arranged for the selection of the needle size from said memory.

13. The automatic injection device of claim 11 wherein said tube is defined by a tube size, wherein said memory includes a plurality of tube sizes and said selector is arranged for the selection of the tube size from said memory.

14. The automatic injection device of claim 11 wherein said syringe is defined by a syringe size and type, wherein said memory includes a plurality of syringe sizes and types and wherein selector is arranged for the selection of the syringe size and type.