Nutraceuticals or nutritional supplements and method of making
First Claim
1. A method of producing a chewing gum product containing a physically-modified active agent in order to control the release rate of the active agent comprising the steps of:
- a) mixing a quantity of an active agent, which comprises one or more materials selected from the group consisting of benzoin , glucosamine, grapeseed extract, guarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lecithin, lycopene, polyphenol, psyllium, chromium picolinate and phenylpropanolamine, with a modifying agent and a high-potency sweetener selected from the group consisting of neotame, aspartame, alitame, salts of acesulfame, cyclamate and its salts, saccharin and its salts, thaumatin, monellin, dihydrochalcones, sucralose and combinations thereof, to form a modified release rate active agent and high-potency sweetener combination;
b) adding a quantity of the combination to a chewing gum formulation to provide an effective amount of the active agent in the chewing gum formulation.
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Accused Products
Abstract
A method for producing a chewing gum with a controlled release active agent, as well as the chewing gum so produced, is obtained by physically modifying the release properties of the active agent, such as a nutraceutical or nutritional supplement, by coating and drying. The active agent is coated by encapsulation, partially coated by agglomeration, entrapped by absorption, or treated by multiple steps of encapsulation, agglomeration, and absorption. The coated active agent is preferably then co-dried and particle sized to produce a release-modified active agent for use in chewing gum. The active agent may also be used in a coating on a chewing gum product, as part of a rolling compound applied to the chewing gum product, or as a part of the liquid in a liquid-center chewing gum product.
259 Citations
42 Claims
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1. A method of producing a chewing gum product containing a physically-modified active agent in order to control the release rate of the active agent comprising the steps of:
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a) mixing a quantity of an active agent, which comprises one or more materials selected from the group consisting of benzoin , glucosamine, grapeseed extract, guarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lecithin, lycopene, polyphenol, psyllium, chromium picolinate and phenylpropanolamine, with a modifying agent and a high-potency sweetener selected from the group consisting of neotame, aspartame, alitame, salts of acesulfame, cyclamate and its salts, saccharin and its salts, thaumatin, monellin, dihydrochalcones, sucralose and combinations thereof, to form a modified release rate active agent and high-potency sweetener combination;
b) adding a quantity of the combination to a chewing gum formulation to provide an effective amount of the active agent in the chewing gum formulation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 16)
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15. A method of producing a chewing gum containing a physically-modified active agent in order to control the release rate of the active agent comprising the steps of:
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a) mixing a quantity of the active agent, which comprises one or more materials selected from the group consisting of benzoin, glucosamine, prapeseed extract, quarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lecithin, lycopene, polyphenol, psyllium, chromium picolinate and phenylpropanolamine, with a high-potency sweetener selected from the group consisting of neotame, aspartame, alitame, salts of acesulfame, cyclamate and its salts, saccharin and its salts, thaumatin, monellin, dihydrochalcones, sucralose and combinations thereof, and an agglomerating agent and solvent to partially coat the active agent, agglomerating agent and high-potency sweetener;
b) removing the solvent from the mixture of active agent, high-potency sweetener and agglomerating agent to form a dried material; and
c) adding a quantity of the dried material to a chewing gum formulation to provide an effective amount of the active agent in the gum. - View Dependent Claims (17, 18)
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- 19. A method of producing a chewing gum product containing an active agent, which comprises one or more materials selected from the group consisting of benzoin, glucosamine, grapeseed extract, guarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lycopene, polyphenol, psyllium, chromium picolinate and phenylpropanolamine, wherein the active agent is a part of a rolling compound applied on the chewing gum product.
- 21. A method of producing a chewing gum product containing an active agent, which comprises one or more materials selected from the group consisting of benzoin, glucosamine, grapeseed extract, guarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lycopene, polyphenol, psyllium, chromium picolinate and phenylpropanolamine, wherein the active agent is part of the liquid in a liquid-center chewing gum product.
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23. A method of producing a chewing gum product containing an absorption-enhanced active agent in order to control the absorption rate of the active agent comprising the steps of:
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a) mixing a quantity of the active agent, which comprises one or more materials selected from the group consisting of nutraceuticals and nutritional supplements, with an absorption enhancing agent selected from the group consisting of ethanol, polytheylene glycol, 2-pyrrolidones, myristic acid, p-phenyl phenol, nitrobenzene, stearyl alcohol, cetyl alcohol, croton oil, liquid paraffin, dimethyl sulfoxide, non-ionic surfactants, liposomes, lecithin fractions, long chain amphipathic molecules and mixtures thereof; and
b) incorporating a quantity of the mixture into a chewing gum formulation to provide an active agent level in the chewing gum formulation of from about 12 micrograms to about 250 milligrams per gram of chewing gum product. - View Dependent Claims (24)
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25. A coated chewing gum product containing an active agent comprising a compound selected from the group consisting of capsicum, chamomile, cat'"'"'s claw, echinacea, garlic, ginger, green tea, golden seal, kava kava, nettle, passion flower, saw palmetto, St. John'"'"'s wort, valerian, benzoin, glucosamine, grapeseed extract, guarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lycopene, polyphenol, psyllium, chromium picolinate, phenylpropanolamine and mixtures thereof, wherein the active agent is a part of a coating on a chewing gum pellet.
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26. A method of producing coated chewing gum products containing at least one active agent in the coating, the active agent comprising a compound selected from the group consisting of capsicum, chamomile, cat'"'"'s claw, echinacea, garlic, ginger, green tea, golden seal, kava kava, nettle, passion flower, saw palmetto, St. John'"'"'s wort, valerian, benzoin, glucosamine, grapeseed extract, guarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lycopene, polyphenol, psyllium, chromium picolinate, phenylpropanolamine and mixtures thereof, comprising the steps of:
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a) providing chewing gum product cores;
b) providing a coating solution;
c) coating the chewing gum product cores with the coating solution to provide coated chewing gum products, the coating including the active agent at a level of from about 12 micrograms to about 250 milligrams per gram of coated chewing gum product. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. A method of producing coated chewing gum products containing at least one active agent in the coating the active agent comprising a compound selected from the group consisting of capsicum, chamomile, cat'"'"'s claw, echinacea, garlic, ginger, green tea, golden seal, kava kava, nettle, passion flower, saw palmetto, St. John'"'"'s wort, valerian, benzoin, glucosamine, grapeseed extract, guarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lycopene, polyphenol, psyllium, chromium picolinate, phenylpropanolamine and mixtures thereof, comprising the steps of:
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a) providing chewing gum product cores;
b) providing a coating solution;
c) coating the chewing gum product cores with the coating solution to provide coated chewing gum products, the coating including the active agent at a level of from about 0.2% to about 5% in the gum products.
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42. A method of producing coated chewing gum products containing at least one active agent in the coating treated so as to modify the absorption of the active agent in the mouth, the active agent comprising a compound selected from the group consisting of capsicum, chamomile, cat'"'"'s claw, echinacea, garlic, ginger, ginko, ginseng, green tea, golden seal, kava kava, nettle, passion flower, saw palmetto, St. John'"'"'s wort, valerian, benzoin, glucosamine, grapeseed extract, guarana, phosphotidylserine, phytosterols, phytochemicals, isoflavones, lecithin, lycopene, polyphenol, psyllium, chromium picolinate, phenylpropanolamine and mixtures thereof, comprising the steps of:
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a) providing chewing gum product cores;
b) providing a coating solution;
c) coating the chewing gum product cores with the coating solution to provide coated chewing gum products, the coating including the active agent at a level of from about 12 micrograms to about 250 milligrams per gram of coated chewing gum product and an absorption enhancing agent selected from the group consisting of ethanol, polytheylene glycol, 2-pyrrolidones, myristic acid, p-phenyl phenol, nitrobenzene, stearyl alcohol, cetyl alcohol, croton oil, liquid paraffin, dimethyl sulfoxide, non-ionic surfactants, liposomes, lecithin fractions, and long chain amphipathic molecules and mixtures thereof.
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Specification