Method and apparatus for programming a rate responsive implantable cardiac stimulation device using user specified rate response functions

• US 6,952,612 B1
• Filed: 04/24/2002
• Issued: 10/04/2005
• Est. Priority Date: 04/24/2002
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Lu, Richard
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US10/132,445
• Time in Patent Office: 1,259 Days
• Field of Search: 607/17, 607/18, 607/27, 607/30, 607/31, 607/59
• US Class Current: 607/30
• CPC Class Codes: A61N 1/37252 Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data

Abstract

Techniques are provided for programming a rate-responsive pacemaker or other implantable cardiac stimulation device capable of rate-responsive pacing. In one embodiment, an external programmer is configured to allow a physician to program the pacemaker with a smooth curvilinear rate-responsive pacing function having whatever shape the physician deems optimal for the patient, rather than being limited to generating a linear or bi-linear rate-responsive pacing functions as with many conventional techniques. The rate-responsive pacing function may specify, for example, pacing rates as a function of orthostatic sensor values, activity sensor values, minute ventilation sensor values, vasovagal syncope sensor values or paced depolarization integral sensor values. If several sensors are provided in the pacemaker, smooth rate-responsive pacing functions may be separately generated for use with each sensor.

Claims

1. In an external programmer for use in programming an implantable cardiac stimulation device having at least one sensor for use in rate-responsive pacing, a programming method comprising:

inputting a set of individual values representative of points defining a desired rate-responsive pacing function;

fitting a curvilinear function to the input values to generate a rate-responsive pacing function from the input values; and

transmitting the rate-responsive pacing function to the implantable cardiac stimulation device for use therein in determining a rate-responsive pacing rate.

2. The method of claim 1 for use in programming a cardiac stimulation device having a plurality of sensors and wherein the method further comprises inputting a value identifying the particular sensor for which the rate-responsive pacing function is to be generated.

3. The method of claim 2 for use in programming a cardiac stimulation device having a plurality of sensors wherein the pacing rate is calculated based on a combination of values from the sensors and wherein the method further comprises:

inputting contribution values representative of relative contributions each sensor of the implantable cardiac stimulation device is to provide in deriving a rate-responsive pacing rate; and

transmitting the contribution values to the cardiac stimulation device for use therein.

4. The method of claim 3 for use in programming a cardiac stimulation device capable of detecting an activity level of the patient and wherein the method further comprises:

inputting separate sets of contribution values to be used by the cardiac stimulation device for separate activity levels; and

transmitting the separate sets of contribution values to the cardiac stimulation device for use therein along with the associated activity levels.

5. The method of claim 1 for use in programming a cardiac stimulation device having one or more of an orthostatic sensor, an activity sensor, a minute ventilation sensor, a vasovagal syncope sensor, a paced depolarization integral sensor, a QT interval sensor, a temperature sensor, an oxygen blood saturation sensor, and a pre-ejection period sensor and wherein inputting a set of individual values representative of points defining a desired rate-responsive pacing function is performed to input pacing rates for various values expected from the particular sensor.

6. The method of claim 1 wherein, for a particular sensor, inputting a set of individual values, fitting a curvilinear function to the input values to generate a rate-responsive pacing function, and transmitting the rate-responsive pacing function to the cardiac stimulation device are performed a plurality of times to program the device with a plurality of rate-responsive pacing functions for the particular sensor.

7. The method of claim 6 wherein the method further comprises:

inputting criteria specifying circumstances under which each of the plurality of rate-responsive pacing functions is to be employed by the cardiac stimulation device; and

transmitting the criteria to the cardiac stimulation device for use therein such that the cardiac stimulation device may be programmed to use different rate-responsive pacing functions under different conditions.

8. The method of claim 7 for use in programming a cardiac stimulation device capable of detecting when the patient is in a bed-rest state and wherein the criteria input specifies that a selected rate-responsive pacing function is to be employed while the bed-rest state is detected.

9. The method of claim 7 for use in programming a cardiac stimulation device capable of detecting when the patient is in an active state and wherein the criteria input specifies that a selected rate-responsive pacing function is to be employed while the active state is detected.

10. The method of claim 7 for use in programming a cardiac stimulation device capable of mode switching and capable of detecting tachyarrhythmia episodes and wherein the criteria input specifies that a selected rate-responsive pacing function is to be employed whenever a predetermined number of tachyarrhythmia episodes are detected following mode switching episodes within a predetermined time period.

11. The method of claim 7 for use in programming a cardiac stimulation device capable of detecting premature atrial contractions and wherein the criteria input specifies that a selected rate-responsive pacing function is to be employed whenever a predetermined number of premature atrial contractions are detected within a predetermined time period.

12. The method of claim 7 for use in programming a cardiac stimulation device capable of detecting premature ventricular contractions and wherein the criteria input specifies that a selected rate-responsive pacing function is to be employed whenever a predetermined number of premature ventricular contractions are detected within a predetermined time period.

13. The method of claim 1 further comprising converting the rate-responsive pacing function to a look-up table of pacing rates as a function of sensor values and wherein transmitting the rate-responsive pacing function to the cardiac stimulation device is performed by transmitting the look-up table to the cardiac stimulation device.

14. A method of programming a cardiac stimulation device having at least one sensor for use in rate-responsive pacing, the method comprising:

inputting a set of individual values representative of points defining a desired rate-responsive pacing function using an external programmer, fitting a curvilinear function to the input values to generate a rate-responsive pacing function, and transmitting the rate-responsive pacing function to the cardiac stimulation device; and

receiving the rate-responsive pacing function within the cardiac stimulation device and converting sensor output values to pacing rates using the rate responsive pacing function.

15. In an external programmer for use in programming an implantable cardiac stimulation device having at least one sensor for use in rate-responsive pacing, a system comprising:

a rate-responsive pacing programming unit operative to input a set of individual values representative of points defining a desired rate-responsive pacing function and to fit a curvilinear function to the input values to generate a rate-responsive pacing function; and

a telemetry unit adapted to transmit the rate-responsive pacing function to the cardiac stimulation device for use therein in determining a rate-responsive pacing rate.

16. A system comprising:

an external programmer having a rate-responsive pacing programming unit operative to input a set of individual values representative of points defining a desired rate-responsive pacing function and to fit a curvilinear function to the input values to generate a rate-responsive pacing function, and a telemetry unit operative to transmit the rate-responsive pacing function to the cardiac stimulation device; and

an implantable cardiac stimulation device having a rate-responsive sensor, a telemetry unit operative to receive the rate-responsive pacing function from the external programmer, and a rate-responsive pacing controller operative to convert output values from the rate-responsive sensor to pacing rates using the rate-responsive pacing function.

17. In an external programmer for use in programming an implantable cardiac stimulation device having at least one sensor for use in rate-responsive pacing, a method comprising:

inputting a set of individual values representative of points defining a desired rate-responsive pacing function;

fitting a curvilinear function to the input values to generate a rate responsive pacing function;

converting the rate-responsive pacing function to a look-up table of pacing rates as a function of sensor values; and

transmitting the look-up table to the cardiac stimulation device for use therein in determining a rate-responsive pacing rate.

18. A system comprising:

an implantable cardiac stimulation device;

an external programmer to program the implantable cardiac stimulation device;

means, within the external programmer, for inputting a set of individual values representative of points defining a desired rate-responsive pacing function;

means, within the external programmer, for fitting a curvilinear function to the input values to generate a rate-responsive pacing function;

means, within the external programmer, for converting the rate-responsive pacing function to a look-up table of pacing rates as a function of sensor values;

means, within the external programmer, for transmitting the look-up table to the implantable cardiac stimulation device for use therein in determining a rate-responsive pacing rate;

means, within the implantable cardiac stimulation device, for receiving the look-up table; and

means, within the implantable cardiac stimulation device, for converting sensor output values to pacing rates using the look-up table.