Medicament delivery system

• US 6,958,691 B1
• Filed: 09/22/2000
• Issued: 10/25/2005
• Est. Priority Date: 10/01/1999
• Status: Expired due to Term

• Current Assignee: GlaxoSmithKline LLC (GlaxoSmithKline PLC)
• Original Assignee: Smithkline Beecham Corporation (Smithkline Beecham PLC)
• Inventors: Bonney, Stanley George, Anderson, Gregor John McLennan, Robertson, Duncan, Jones, Anthony Patrick
• Primary Examiner(s): MULLEN, THOMAS J
• Application Number:
  US10/089,760
• Time in Patent Office: 1,859 Days
• Field of Search: 340/573.1, 340/539.11, 340/539.12, 340/539.13, 705/2, 705/3, 128/200.14, 128/200.21
• US Class Current: 340/539.12
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/083 Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61J 7/0418 with electronic history memory
• CPC Class Codes: A61J 7/0436 resulting from removing a drug from, or opening, a container
• CPC Class Codes: A61J 7/0463 for multiple patients
• CPC Class Codes: A61J 7/0481 working on a schedule basis
• CPC Class Codes: A61M 15/008 Electronic counters
• CPC Class Codes: A61M 15/009 using medicine packages with incorporated spraying means, e.g. aerosol cans pocket atomiser of the injector type A61M11/08
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: G06F 21/31 User authentication
• CPC Class Codes: G06F 21/6245 Protecting personal data, e.g. for financial or medical purposes
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/13 delivered from dispensers
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 70/60 relating to pathologies

Abstract

There is provided a system for the delivery of medicament comprising a medicament container; a dispensing mechanism for dispensing medicament from the medicament container; an electronic data management system; and a communicator for wireless communication with a network computer system to enable communication of data between the network computer system and the electronic data management system. The electronic data management system comprises a memory for storage of data; a microprocessor for performing operations on the data; and a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data.

Claims

1. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

wherein the data is communicable between the network computer system and the electronic data management system in encrypted form.

2. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising, an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

wherein the communicator includes an embedded network server.

3. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

wherein the communicator communicates with the network computer system via a second communications device having telecommunications capability.

4. A portable device according to claim 3, wherein the telecommunications device comprises a cellular phone or pager.

5. A portable device according to claim 3, wherein the communicator communicates with the second communications device using spread spectrum radiofrequency signals.

6. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

wherein the network computer system comprises a private access network computer system.

7. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

wherein the communicator enables communication with a user-specific network address in the network computer system

wherein the user-specific network address is selected from the group consisting of a web-site address, an e-mail address and a file transfer protocol address.

8. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

wherein the communicator enables communication with a user-specific network address in the network computer system

wherein the user-specific network address is accessible to a remote information source such that information from said remote information source can be made available to said user-specific network address.

9. A portable device according to claim 8, wherein information from the user-specific network address can be made available to the remote information source.

10. A portable device according to claim 8, wherein the remote information source is a medicament prescriber.

11. A portable device according to claim 8, wherein the remote information source is a pharmacy.

12. A portable device according to claim 8, wherein the remote information source is an emergency assistance provider.

13. A portable device according to claim 8, wherein the remote information source is a manufacturer of medicament or medicament delivery systems.

14. A portable device according to claim 8, wherein the remote information source is a research establishment.

15. A portable device according to claim 8, wherein the remote information source is an environmental monitoring station.

16. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a datalink for linking to a local data store to enable communication of data between the local data store and the microprocessor.

17. A portable device according to claim 16, wherein the datalink comprises an infrared emitter and sensor.

18. A portable device according to claim 16, wherein the local data store comprises a personal computer or set-top box.

19. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operator on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a data input system for user input of data to the electronic data management system.

20. A portable device according to claim 19, wherein said data input system comprises a man machine interface selected from the group consisting of a keypad, voice recognition interface, graphical user interface (GUI) or biometrics interface.

21. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispenser mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

wherein said electronic data management system includes a predictive algorithm or look-up table for calculating the optimum amount of medicament to dispense.

22. A portable device according to claim 21, wherein the memory includes a dose memory for storing dosage data and reference is made to the dose memory in calculating the optimum amount of medicament to dispense.

23. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a geographic positioning system.

24. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network commuter system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a sensor which senses the breath of a user, wherein the sensor communicates breath data to the electronic data management system, wherein said sensor comprises a breath-movable element which is movable in response to the breath of a patient.

25. A portable device according to claim 24, wherein said breath-movable element is selected from the group consisting of a vane, a sail, a piston and an impeller.

26. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a sensor which senses the breath of a user, wherein the sensor communicates breath data to the electronic data management system, wherein the sensor comprises a pressure sensor for sensing the pressure profile associated with the breath of a user.

27. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a sensor which senses the breath of a user, wherein the sensor communicates breath data to the electronic data management system, wherein the sensor comprises a moisture sensor for sensing the moisture profile associated with the breath of a user.

28. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitting for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a sensor which senses the breath of a user, wherein the sensor communicates breath data to the electronic data management system, wherein the sensor comprises a gas sensor for sensing the oxygen or carbon dioxide profile associated with the breath of a user.

29. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a sensor which senses the breath of a user, wherein the sensor communicates breath data to the electronic data management system, wherein said breath data includes breath cycle data.

30. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a sensor which senses the breath of a user, wherein the sensor communicates breath data to the electronic data management system, wherein said breath data includes peak flow data.

31. A portable device for the delivery of medicament comprising

a housing;

received by said housing, a medicament container;

associated with said medicament container, a dispensing mechanism for dispensing medicament from the medicament container;

said portable device further comprising an electronic data management system comprising

a memory for storage of data concerning use of said portable device;

a microprocessor for performing operations on said data; and

a transmitter for transmitting a signal relating to the data or the outcome of an operation on the data; and

associated with the electronic data management system, a communicator for wireless communication with a remote network computer system to enable two-way transfer of data between the network computer system and the electronic data management system

additionally comprising a sensor which senses the breath of a user, wherein the sensor communicates breath data to the electronic data management system,

additionally comprising an actuator for actuating the dispensing mechanism, said actuator being actuable in response to a trigger signal from the transmitter.

32. A portable device according to claim 31, wherein the electronic data management system includes a predictive algorithm or look-up table for deriving from the breath data when to transmit the trigger signal.

33. A portable device according to claim 31, wherein said actuator comprises an energy store for storing energy which energy is releasable to actuate the dispensing mechanism of the medicament container.