Integrated blood handling system having active gas removal system and methods of use

• US 6,960,322 B2
• Filed: 07/08/2003
• Issued: 11/01/2005
• Est. Priority Date: 02/09/2001
• Status: Expired due to Fees

• Current Assignee: ARG Medical Solutions LLC
• Original Assignee: Cardionet Incorporated
• Inventors: Brian, Ben F. III, Afzal, Thomas A., Dueri, Jean-Pierre, Linker, Fred I., Farhangnia, Mehrdad, Hultquist, Kevin L., Stringer, Steven K., Culp, James M.
• Primary Examiner(s): Bianco, Patricia
• Application Number:
  US10/616,116
• Publication Number:
  US 20040009097A1
• Time in Patent Office: 847 Days
• Field of Search: 604/4.01, 604/6.01, 604/6.14, 604/6.16, 604/6.11, 604104-109, 604/264, 604174- 5, 422 44- 48, 210758-760, 261/19, 261/24, 261/28, 261/29, 261/30, 261/35, 261/34.1, 261/36.1, 261/DIG.28, 128/898, 423/235
• US Class Current: 422/45
• CPC Class Codes: A61M 1/262 rotating
• CPC Class Codes: A61M 1/267 used for pumping
• CPC Class Codes: A61M 1/3603 in the same direction
• CPC Class Codes: A61M 1/3606 Arrangements for blood-volume reduction of extra-corporeal circuits
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 1/3626 Gas bubble detectors
• CPC Class Codes: A61M 1/3627 Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
• CPC Class Codes: A61M 1/3666 Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
• CPC Class Codes: A61M 60/109 incorporated within extracorporeal blood circuits or systems
• CPC Class Codes: A61M 60/113 in other functional devices, e.g. dialysers or heart-lung machines
• CPC Class Codes: A61M 60/232 Centrifugal pumps
• CPC Class Codes: A61M 60/38 Blood oxygenation
• CPC Class Codes: A61M 60/40 Details relating to driving
• CPC Class Codes: A61M 60/818 Bearings
• CPC Class Codes: F04D 9/006 by venting gas or using gas valves
• CPC Class Codes: Y10S 261/28 Blood oxygenators

Abstract

Apparatus and methods for pumping and oxygenating blood are provided that include a gas removal system. An integrated blood processing unit is provided in which a gas removal/blood filter, pump and blood oxygenation element are mounted within a common housing. The gas removal system includes a sensor mounted on the housing to sense the presence of gas, and a valve is operably coupled to the sensor to evacuate gas from the system when the sensor detects an accumulation of gas.

Claims

1. Apparatus for oxygenating and pumping blood comprising:

a venous line;

an arterial line;

a gas removal system coupled to the venous line, the gas removal system comprising a housing having a gas collection plenum and a gas removal port and a filter element disposed within the housing;

a blood oxygenation element having a blood outlet coupled to the arterial line;

a pump coupled in fluid communication with the blood oxygenation element, the pump coupled directly to the gas removal system to induce a negative pressure in the gas removal system and the venous line;

a sensor disposed on the gas collection plenum to monitor a level of gas or blood in the gas collection plenum;

a suction line coupled to the gas removal port;

a valve operatively associated with the suction line;

a microprocessor-based controller coupled to the sensor to continuously monitor the level of gas or blood in the gas collection plenum, the controller programmed to selectively actuate the valve to remove gas accumulated in the gas collection plenum; and

a control panel coupled to the controller, the control panel configured to accept input commands that control operation of the gas removal system.

2. The apparatus of claim 1 further comprising at least a first pole-mounted support arm for supporting the gas removal system, the blood oxygenation element and the pump.

3. The apparatus of claim 2 further comprising at least a second pole-mounted support arm for supporting the control panel.

4. The apparatus of claim 1 wherein the sensor comprises an ultrasonic sensor.

5. The apparatus of claim 1 wherein the sensor comprises a capacitive sensor.

6. The apparatus of claim 1 wherein the blood oxygenation element comprises an annular fiber bundle.

7. The apparatus of claim 1 wherein the gas removal system, blood oxygenation element and pump are coupled together in a fixed, predetermined arrangement.

8. The apparatus of claim 1 wherein the filter element comprises a first stage of a multi-stage blood filter.

9. The apparatus of claim 1 further comprising a recirculation line coupled between blood outlet and the gas removal system.

10. The apparatus of claim 1 wherein the pump comprises an impeller that is magnetically coupled to a reusable drive unit.

11. The apparatus of claim 1, further comprising a heat exchanger coupled between the venous line and the arterial line.

12. Apparatus for oxygenating and pumping blood comprising:

a venous line;

an arterial line; and

a blood circuit coupled between the venous line and the arterial line, the blood circuit comprising a gas removal system, a pump and an oxygenator coupled together in a fixed, predetermined arrangement, wherein the pump is coupled in fluid communication between the oxygenator and the gas removal system to induce a negative pressure in the gas removal system and the venous line; and

wherein the gas removal system is coupled to the venous line and comprises;

a housing having a gas collection plenum and a gas removal port,

a sensor disposed on the housing to monitor a level of gas or blood in the gas collection plenum;

a suction line coupled to the gas removal port;

a valve operatively associated with the suction line;

a microprocessor-based controller coupled to the sensor to continuously monitor the level of gas or blood in the gas collection plenum, the controller programmed to selectively actuate the valve to remove gas accumulated in the gas collection plenum; and

a control panel coupled to the controller, the control panel configured to accept input commands that control operation of the gas removal system.

13. The apparatus of claim 12 wherein the sensor employs ultrasonic energy.

14. The apparatus of claim 13 further comprising at least a first pole-mounted support arm for supporting the blood circuit.

15. The apparatus of claim 14 further comprises at least a second pole-mounted support arm for supporting the control panel.

16. The apparatus of claim 12, wherein the gas removal system further comprises a filter element disposed within the housing.

17. The apparatus of claim 16 wherein the filter element comprises a first stage of a multi-stage blood filter.

18. The apparatus of claim 16 wherein the pump comprises an impeller that is magnetically coupled to a reusable drive unit.

19. The apparatus of claim 12 further comprising a recirculation line coupled between the oxygenator and the gas removal system.

20. The apparatus of claim 12 wherein the sensor comprises a capacitive sensor.

21. The apparatus of claim 12 further comprising a heat exchanger coupled between the venous line and the arterial line.