Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
First Claim
1. A reagent test strip for use in detecting the presence or determining the concentration of an analyte in a physiological sample, said strip comprising:
- a positively charged porous matrix; and
a peroxide producing signal producing system present on said matrix, wherein said peroxide producing signal producing system includes a urea derivative dye.
7 Assignments
0 Petitions
Accused Products
Abstract
Compositions, reagent test strips, analyte detection systems and kits of the same, as well as methods for their use in the detection of an analyte in a sample, are provided. The subject compositions are characterized by having a positively charged porous matrix and a urea derivative dye on at least one surface of the matrix, where in many preferred embodiments the urea derivative dye is a negatively charged urea derivative dye. In many preferred embodiments, the subject compositions further include at least one additional reagent member of a peroxide producing signal producing system, e.g., an analyte oxidase and/or a peroxidase. The subject compositions, test strips, analyte detection systems and kits find use in the detection of a wide variety of analytes in a sample, such as a physiological sample, e.g., blood or a fraction thereof.
113 Citations
3 Claims
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1. A reagent test strip for use in detecting the presence or determining the concentration of an analyte in a physiological sample, said strip comprising:
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a positively charged porous matrix; and
a peroxide producing signal producing system present on said matrix, wherein said peroxide producing signal producing system includes a urea derivative dye. - View Dependent Claims (2, 3)
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Specification
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- Resources
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Current AssigneeCilag Gmbh International (Johnson & Johnson)
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Original AssigneeLifescan Incorporated (Duv Holding Corporation)
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InventorsLeong, Koon-wah, Guo, Sherry X.
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Primary Examiner(s)Gitomer, Ralph
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Application NumberUS10/732,389Publication NumberTime in Patent Office693 DaysField of Search422/60, 435/28, 436/904US Class Current422/420CPC Class CodesC12Q 1/28 involving peroxidaseG01N 33/521 Single-layer analytical ele...
