Topical spray compositions
First Claim
1. An aerosol spray composition for topical application comprising:
- about 1% Alendronate sodium,about 6% povidone,about 4% povidone vinyl acetate,about 0.5% vitamin E,about 0.05% menthol,about 3% dimethyl isosorbide,about 10% acetone,about 10% ethanol,about 25.45% tetrafluroroethane and,about 40% dichlorodifluoromethane.
2 Assignments
0 Petitions
Accused Products
Abstract
A topical, medicinal spray composition is provided comprising a drug or combination of drugs in a carrier which, when sprayed on a surface, forms a film. The composition comprises at least one medicament, at least one film former and at least one vehicle. The composition of the invention may further comprise at least one permeation enhancer, at least one solubilizer, at least one plasticizer, and at least one water soluble additive. A metered dose of the composition can be sprayed on a topical site to form a stable, breathable film, preferably over a fixed surface area. A wide range of medicaments for human and veterinary use may be present that act locally or transdermally.
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Citations
3 Claims
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1. An aerosol spray composition for topical application comprising:
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about 1% Alendronate sodium, about 6% povidone, about 4% povidone vinyl acetate, about 0.5% vitamin E, about 0.05% menthol, about 3% dimethyl isosorbide, about 10% acetone, about 10% ethanol, about 25.45% tetrafluroroethane and, about 40% dichlorodifluoromethane.
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2. A sprayable composition for topical ad ministration comprising:
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about 0.5 to about 15% at a medicament, about 6% povidone, about 4% povidone vinyl acetate, about 0.5% vitamin E, about 5% dimethyl isosorbide, about 20% ethanol and, trichloromonfluoromethane.
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3. A sprayable composition for topical administration comprising:
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about 1% estradiol, about 6% povidone, about 4% povidone vinyl acetate, about 1% vitamin E, about 0.05 menthol, about 5% dimethyl isosorbide, about 27.5% acetone, about 27.5% ethanol and about 27.5% trichlomonofluoromethane.
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Specification
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- Resources
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Current AssigneeCipla (EU) Limited (Cipla Limited)
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Original AssigneeU & I Pharmaceuticals, Ltd.
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InventorsLulla, Amar, Malhotra, Geena, Raut, Preeti
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Primary Examiner(s)Low, Christopher S. F.
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Assistant Examiner(s)Lewis, Amy
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Application NumberUS09/503,843Time in Patent Office2,093 DaysField of Search424/45, 424/81, 424/448, 424/434US Class Current424/45CPC Class CodesA61K 2300/00 Mixtures or combinations of...A61K 31/565 not substituted in position...A61K 45/06 Mixtures of active ingredie...A61K 9/12 Aerosols; Foams A61K9/0043,...A61K 9/7015 Drug-containing film-formin...A61L 2/0082 using chemical substances
