Needleless Safety Syringe of Compact Architecture

• US 6,964,650 B2
• Filed: 10/19/2001
• Issued: 11/15/2005
• Est. Priority Date: 10/23/2000
• Status: Expired due to Term

• Current Assignee: Crossject SA
• Original Assignee: Crossject SA
• Inventors: Piel, Marc, Alexandre, Patrick, Gautier, Philippe, Brouquieres, Bernard
• Primary Examiner(s): Lucchesi, Nicholas D.
• Assistant Examiner(s): Han, Mark K.
• Application Number:
  US10/398,768
• Publication Number:
  US 20040015125A1
• Time in Patent Office: 1,488 Days
• Field of Search: 604/68, 604/69, 604/70, 604/71, 604/72, 604/73, 604/131, 604/140, 604/141, 604/143, 604/145, 604/187
• US Class Current: 604/70
• CPC Class Codes: A61M 5/2046 Media being expelled from injector by gas generation, e.g. explosive charge
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules

Abstract

The technical field is that of pre-filled disposable needleless syringes, operating with a gas generator (100) and used for intradermal, subcutaneous and intramuscular injections of liquid active principle for therapeutic purposes in human and veterinary medicine. The inventive needleless syringe (1) is characterised in that it comprises a compact architecture body (2) and the gas generator (100) is released by a cap (17) covering said body (2), said cap (17) being adapted to slide along said body (2). Said releasing mode provides the syringe with great stability (1) at the time of injection.

Claims

1. A needleless syringe comprising a body, a gas generator, a chamber for expansion of said gases, a reservoir containing the active principle, and an injection system having at least one injection channel, characterized in that the body has a compact architecture inducing the misalignment of the gas generator and of the reservoir containing the active principle, and the gas generator is triggered by a cap which covers said body, said cap being able to slide along said body.

2. The needleless syringe as claimed in claim 1, characterized in that the gas generator is a pyrotechnic gas generator comprising a pyrotechnic charge and an initiation device.

3. The needleless syringe as claimed in claim 1, characterized in that, on the one hand, the gas generator constitutes a first linear subassembly of the body, and, on the other hand, the reservoir containing the active principle and the injection system form a second linear subassembly of said body, the two subassemblies forming between them an angle of less than or equal to 90°

and being connected to one another via the expansion chamber.

4. The needleless syringe as claimed in claim 3, characterized in that the two subassemblies have mutually parallel axes and are connected to one another via the expansion chamber which has an axis perpendicular to the axes of said subassemblies.

5. The needleless syringe as claimed in claim 4, characterized in that the cap is able to slide along the body on an axis parallel to those of the two subassemblies.

6. The needleless syringe as claimed in claim 1, characterized in that the ratio of the maximum height of said syringe to its maximum length is between 0.8 and 1.8.

7. The needleless syringe as claimed in claim 1, characterized in that a compression member is arranged between the cap and the body in such a way as to push said cap back from said body.

8. The needleless syringe as claimed in claim 1, characterized in that the reservoir is formed by a tube obturated by an upstream piston plug and a downstream piston plug between which the active principle is contained.

9. The needleless syringe as claimed in claim 1, characterized in that the cap completely covers the body and the injection system emerges from said cap.

10. The needleless syringe as claimed in claim 1, characterized in that the injection system and the cap cooperate in order to trigger said syringe.

11. The needleless syringe as claimed in claim 1, characterized in that the cap is continued by a stopper covering the injection system, said stopper having substantially the same cross section as that of the cap which it continues.

12. The needleless syringe as claimed in claim 1, characterized in that the cap has a means for securing it to the body, allowing it to remain in a position of maximum engagement.

13. A needleless syringe comprising a body, a gas generator, a chamber for expansion of said gases, a reservoir containing the active principle, and an injection system having at least one injection channel, characterized in that the body has a compact architecture inducing the misalignment of the gas generator and of the reservoir containing the active principle, and the gas generator is triggered by a cap which covers said body, said cap being able to slide along said body, characterized in that the injection system ends in a retractable protective plate.

14. A needleless syringe comprising a body, a gas generator, a chamber for expansion of said gases, a reservoir containing the active principle, and an injection system having at least one injection channel, characterized in that the body has a compact architecture inducing the misalignment of the gas generator and of the reservoir containing the active principle, and the gas generator is triggered by a cap which covers said body, said cap being able to slide along said body, characterized in that the cap (is continued by a stopper covering the injection system, said stopper having substantially the same cross section as that of the cap which it continues, and the stopper a) has a plane base, b) is connected to the injection system via a system of bayonets, and c) obturates the cap by being in contact with it and in its continuity.

15. A needleless syringe comprising a body, a gas generator, a chamber for expansion of said gases, a reservoir containing the active principle, and an injection system having at least one injection channel, characterized in that the body has a compact architecture inducing the misalignment of the gas generator and of the reservoir containing the active principle, and the gas generator is triggered by a cap which covers said body, said cap being able to slide along said body, characterized in that the gas generator is a pyrotechnic gas generator comprising a pyrotechnic charge and an initiation device, the initiation device comprises a primer and a percussion device which includes a spring and a striker, said striker being in the form of a hollow cylindrical component which is provided at one of its ends with a projection and has, on its outer lateral surface, at least two lugs, each having an inwardly curved inclined plane, said striker enclosing said spring.

16. The needleless syringe as claimed in claim 15, characterized in that the hollow cylindrical component has, on its outer lateral surface, at least two protuberances of substantially parallelepipedal shape, said protuberances bearing against at least two limit stops on the body in order to prevent the striker from being translated under the action of the spring.

17. The needleless syringe as claimed in claim 16, characterized in that the cap has, on the one hand, at least two locking stubs which bear against the protuberances of the striker in order to prevent said striker from undergoing a rotation about its axis, and, on the other hand, at least two overhangs which each end in an inwardly curved inclined plane, in such a way that the sliding of the cap along the body causes both the translation of the stubs, so as to free the striker in terms of rotation, and also the translation of said overhangs which come into contact with the lugs on the striker at the level of their respective inclined planes which engage each other, bringing about the rotation of said striker and the misalignment of the protuberances with the limit stops on the body.