Tissue ablation device assembly and method of electrically isolating a pulmonary vein ostium from an atrial wall
First Claim
1. A tissue ablation system for treating atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:
- a delivery member having a proximal end portion and a distal end portion with a longitudinal axis and a radial axis;
a housing with a distal wall, that is located at least in part along the distal end portion, and that is mechanically adjustable between a first condition and a second condition, wherein the first condition the distal wall is substantially radially collapsed such that the housing is adapted to be delivered through a delivery sheath into the atrium, and wherein the second condition the distal wall is radially extended at least in part from the longitudinal axis with a distal orientation and a distal facing surface located along a circumferential region that surrounds the longitudinal axis;
a mechanical positioning assembly coupled to the housing to mechanically adjust the housing between the first and second conditions; and
an ablation element cooperating with the housing and which is adapted to ablatively couple to a circumferential area normal to the distal facing surface along the circumferential region when the housing is in the second position, wherein the ablation element and distal facing surface are configured such that the circumferential area coincides with the circumferential region of tissue when the housing is adjusted to the second condition at the location, and wherein in the second condition the distal wall along the circumferential region comprises a porous membrane that encloses at least in part a fluid chamber within the housing;
the distal facing surface is located along the porous membrane; and
the porous membrane is adapted to ablatively couple a volume of ablative fluid within the fluid chamber to the circumferential area.
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Abstract
This invention is related to a tissue ablation system and method that treats atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium. The system includes a circumferential ablation member with an ablation element and also includes a delivery assembly for delivering the ablation member to the location. The circumferential ablation member is generally adjustable between different configurations to allow both the delivery through a delivery sheath into the atrium and the ablative coupling between the ablation element and the circumferential region of tissue.
394 Citations
19 Claims
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1. A tissue ablation system for treating atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:
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a delivery member having a proximal end portion and a distal end portion with a longitudinal axis and a radial axis;
a housing with a distal wall, that is located at least in part along the distal end portion, and that is mechanically adjustable between a first condition and a second condition, wherein the first condition the distal wall is substantially radially collapsed such that the housing is adapted to be delivered through a delivery sheath into the atrium, and wherein the second condition the distal wall is radially extended at least in part from the longitudinal axis with a distal orientation and a distal facing surface located along a circumferential region that surrounds the longitudinal axis;
a mechanical positioning assembly coupled to the housing to mechanically adjust the housing between the first and second conditions; and
an ablation element cooperating with the housing and which is adapted to ablatively couple to a circumferential area normal to the distal facing surface along the circumferential region when the housing is in the second position, wherein the ablation element and distal facing surface are configured such that the circumferential area coincides with the circumferential region of tissue when the housing is adjusted to the second condition at the location, and wherein in the second condition the distal wall along the circumferential region comprises a porous membrane that encloses at least in part a fluid chamber within the housing;
the distal facing surface is located along the porous membrane; and
the porous membrane is adapted to ablatively couple a volume of ablative fluid within the fluid chamber to the circumferential area. - View Dependent Claims (2, 3, 4, 5)
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6. A tissue ablation system for treating atrial arrhythmia by ablating a circumferential region of tissue at a location where a pulmonary vein extends from an atrium, comprising:
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a delivery member having a proximal end portion and a distal end portion with a longitudinal axis and a radial axis;
a housing with a distal wall, that is located at least in part along the distal end portion, and that is mechanically adjustable between a first condition and a second condition, wherein the first condition the distal wall is substantially radially collapsed such that the housing is adapted to be delivered through a delivery sheath into the atrium, and wherein the second condition the distal wall is radially extended at least in part from the longitudinal axis with a distal orientation and a distal facing surface located along a circumferential region that surrounds the longitudinal axis;
a mechanical positioning assembly coupled to the housing, to mechanically adjust the housing between the first and second conditions, and to the delivery member; and
an ablation element cooperating with the housing and which is adapted to ablatively couple to a circumferential area normal to the distal facing surface along the circumferential region when the housing is in the second position, wherein the ablation element and distal facing surface are configured such that the circumferential area coincides with the circumferential region of tissue when the housing is adjusted to the second condition at the location. - View Dependent Claims (7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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Specification