Bandage, methods of producing and using same

• US 6,967,261 B1
• Filed: 12/28/2001
• Issued: 11/22/2005
• Est. Priority Date: 12/28/2001
• Status: Expired due to Term

• Current Assignee: O&M Halyard, Inc. (Owens and Minor Incorporated)
• Original Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Inventors: Soerens, Dave Allen, Malik, Sohail
• Primary Examiner(s): Lucchesi, Nicholas D.
• Assistant Examiner(s): LEWIS, AARON J
• Application Number:
  US10/034,906
• Time in Patent Office: 1,425 Days
• Field of Search: 602 41- 48, 602/1, 602/8, 602/52, 602/54, 602/56, 424444-449, 604304-308
• US Class Current: 602/48
• CPC Class Codes: A61L 15/225 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/608 having two or more layers
• CPC Class Codes: C08L 5/08 Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
• CPC Class Codes: C08L 71/02 Polyalkylene oxides

Abstract

A bandage of the type used on acute wounds, minor wounds, burn wounds and irritations, includes a first layer for covering the wound site and an area around the wound site, with the first layer including a top surface and bottom surface; a second layer over the first layer bottom surface, for absorbing exudates from the wound site; the second layer including a poly(ethyleneoxide)-based compound and a chitosan-based compound. A third layer is situated over the second layer, the third layer being of a perforated film, and wherein, at least one antimicrobial agent is associated with the bandage in a position where the antimicrobial agent will come in contact with the wound site, and which is transferable from the bandage to the wound site, upon contact with the wound site.

Claims

1. A bandage of the type used on acute wounds, burn wounds and irritations comprising:

a first layer for covering a wound site and an area around the wound site, said first layer including a top surface and bottom surface;

a second layer over said first layer bottom surface, for absorbing exudates from the wound site;

said second layer including a crosslinked poly(ethyleneoxide)-based resin that has been modified by grafting with an alkoxy silane functional group and a chitosan-based compound, and wherein

at least one wound healing antimicrobial agent is associated with the bandage in a position where said wound healing antimicrobial agent will come in contact with the wound site, and which is transferable from the bandage to the wound site, upon contact with the wound site.

2. The bandage of claim 1, wherein said concentration of said resin is between about 0.1 and 6 weight percent in solution.

3. The bandage of claim 2, wherein said concentration of said resin is between about 0.1 and 4 weight percent in solution.

4. The bandage of claim 1 wherein said bandage is an adhesive bandage wherein an adhesive layer for adhesively bonding the bandage to a wound site is positioned between said first layer and said second layer.

5. The bandage of claim 1 wherein said wound healing antimicrobial agent is selected from niacinamide ascorbate and Chitosan niacinamide ascorbate.

6. The bandage of claim 1, wherein said wound healing antimicrobial agent is situated in or on the second layer.

7. The bandage of claim 1 wherein the second layer is a film.

8. The bandage of claim 1 wherein the second layer is a fibrous material.

9. The bandage of claim 1 wherein the second layer is either a film or fibrous material that has been coated with the poly(ethylene oxide)-based material and chitosan based material.

10. The bandage of claim 1 further including a perforated anti-stick film layer over said second layer.

11. The bandage of claim 10, wherein said perforated anti-stick film layer is treated with a wound healing antimicrobial material that is transferable to a wound site.

16. The bandage of claim 1 wherein said chitosan in the bandage is between about 0.01 and 75% of the second layer.

17. The bandage of claim 1 wherein the range of wound healing antimicrobial agent is between about 0.1 and 70% by weight of the second layer.

12. A bandage of the type used on acute wounds, burn wounds and irritations comprising:

a first layer for covering the wound site and an area around the wound site, said first layer including a top surface and bottom surface;

a second layer over said first layer, bottom surface, for absorbing exudates from the wound site;

said second layer including a poly(ethyleneoxide)-based compound that has been modified by grafting with an alkoxy silane functional group and a chitosan-based compound,

a third layer over said second layer, said third layer being of a perforated anti-stick film layer, and wherein, at least one wound healing antimicrobial agent is associated with the bandage in a position where said wound healing antimicrobial agent will come in contact with the wound site, and which is transferable from the bandage to the wound site, upon contact with the wound site.

13. The bandage of claim 12 further including an adhesive layer between said first layer and said second layer, for adhesively bonding the bandage to a wound site.

14. The bandage of claim 12 wherein said wound healing antimicrobial agent is selected from niacinamide ascorbate and Chitosan niacinamide ascorbate.

15. The bandage of claim 12 wherein said wound healing antimicrobial agent situated on the perforated anti-stick film layer.