Implantable drug delivery system responsive to intra-cardiac pressure
First Claim
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1. An implantable medical device comprising:
- a pressure monitor that estimates a pulmonary artery diastolic pressure as a function of a pressure in a heart of a patient; and
a processor that selects one of a first dosage and a first dosage rate of a therapeutic drug that corresponds to the estimated pulmonary artery diastolic (EPAD) pressure to maintain said ePAD pressure within a range of approximately about 12 mmHg to about 18 mmHg and that selects one of a second dosage and a second dosage rate of the therapeutic drug for a ePAD within a second range, wherein the second range is different than the first range.
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Abstract
The invention is directed to techniques for monitoring the condition of a patient, such as a patient having congestive heart failure, and appropriately modifying the patient'"'"'s drug therapy as a function of a pressure in the patient'"'"'s heart, such as the estimated pulmonary artery diastolic pressure. The drugs may be administered by an implanted drug delivery device. The drug selection, the drug dosage or both may be controlled as a function of the pressure and/or the activity level of the patient.
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Citations
25 Claims
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1. An implantable medical device comprising:
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a pressure monitor that estimates a pulmonary artery diastolic pressure as a function of a pressure in a heart of a patient; and
a processor that selects one of a first dosage and a first dosage rate of a therapeutic drug that corresponds to the estimated pulmonary artery diastolic (EPAD) pressure to maintain said ePAD pressure within a range of approximately about 12 mmHg to about 18 mmHg and that selects one of a second dosage and a second dosage rate of the therapeutic drug for a ePAD within a second range, wherein the second range is different than the first range. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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Specification