Surgically implanted time release medication for post-surgical treatment of a patient

• US 6,969,525 B2
• Filed: 06/08/2002
• Issued: 11/29/2005
• Est. Priority Date: 06/08/2002
• Status: Expired due to Fees

• Current Assignee: James C.Y. Chow
• Original Assignee: James C.Y. Chow
• Inventors: Chow, James C. Y.
• Primary Examiner(s): Kunz, Gary
• Assistant Examiner(s): Haghighatian, Mina
• Application Number:
  US10/165,549
• Publication Number:
  US 20030228356A1
• Time in Patent Office: 1,270 Days
• Field of Search: 424/422, 424/423, 424/424, 424/426, 424/443, 424/444, 424/489, 530/356, 530/342, 514/21
• US Class Current: 424/423
• CPC Class Codes: A61K 9/0024 Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue compositions for intravenous administration, normal injectable solutions or dispersions for, e.g. subcutaneous administration A61K9/0019; brain implants A61K9/0085; (coated) prostheses, catheters or stents A61L
• CPC Class Codes: A61K 9/5084 Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs tablets containing such a mixture A61K9/2077
• CPC Class Codes: A61L 2300/402 Anaestetics, analgesics, e.g. lidocaine
• CPC Class Codes: A61L 2300/602 Type of release, e.g. controlled, sustained, slow
• CPC Class Codes: A61L 2300/62 Encapsulated active agents, e.g. emulsified droplets
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence

Abstract

A method of administering a medication to a post operative patient with the medication being administered at the site of a surgery performed on the patient. The medication is formed into a time release capsule (10) having a core (12) of the medication which is dispensed within the body over a predetermined period of time. The capsule is covered with a coating (14) that dissolves within the body. The time release medication is not released until the covering is sufficiently dissolved to expose the medication. During surgery, the surgeon places placing a plurality of capsules (10–10n) in the patient'"'"'s body at the surgery site. The respective capsules have different coating thicknesses so the medication contained therein is dispensed at different periods of time after the surgery as a function of the thickness of the coating.

Claims

1. A method of administering a medication to a post operative patient with the medication being administered at the site of a surgery performed on the patient, comprising:

incorporating the medication in a time release capsule for the medication to be dispensed within the body over a period of time;

covering the capsule with a coating dissolved within the body, the medication being released when the covering is sufficiently dissolved to expose the medication, and,

placing a plurality of capsules having different thicknesses of coating in the patient'"'"'s body at the surgery site during the surgery for the medication contained therein to be dispensed into the patient'"'"'s body at different periods of time after the surgery as a function of the thickness of a capsule'"'"'s coating, the dosages contained in respective capsules varying with capsules having a higher dosage of medication having a thinner coating than those capsules having a thicker coating whereby a capsule containing a higher dosage of medication releases its medication into the patient'"'"'s body sooner after the surgery than a capsule with a thicker coating and a lower dosage of medication, and the patient receives medication over a prolonged period of time.

2. The method of claim 1 in which all of the capsules contain the same dosage of the medication.

3. The method of claim 2 in which all the capsules contain the same type of medication.

4. The method of claim 1 wherein some of the capsules contain a first type of medication, and other of the capsules contain a second type of medication, the first and second types of medication being released at different points in time during a post operative period.

5. The method of claim 1 in which each capsule contain at least two different types of medication.