Tunable spectroscopic source with power stability and method of operation

• US 6,980,573 B2
• Filed: 12/09/2002
• Issued: 12/27/2005
• Est. Priority Date: 12/09/2002
• Status: Expired due to Term

• Current Assignee: Infraredx Incorporated (Nipro Corporation)
• Original Assignee: Infraredx Incorporated (Nipro Corporation)
• Inventors: Korn, Jeffrey A.
• Primary Examiner(s): Harvey, Minsun Oh
• Assistant Examiner(s): Nguyen, Tuan N.
• Application Number:
  US10/314,648
• Publication Number:
  US 20040109478A1
• Time in Patent Office: 1,114 Days
• Field of Search: 372/29.022, 372 20- 33, 372/8, 372/109, 600/342, 600324-326, 600476-478, 606/2, 606/3, 606/7, 606/8, 606/15, 359/330, 359326-332
• US Class Current: 372/20
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/0086 using infrared radiation
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: H01S 3/08 Construction or shape of optical resonators or components thereof
• CPC Class Codes: H01S 3/1055 one of the reflectors being constituted by a diffraction grating
• CPC Class Codes: H01S 5/068 Stabilisation of laser output parameters H01S5/0625 takes precedence
• CPC Class Codes: H01S 5/1039 Details on the cavity length
• CPC Class Codes: H01S 5/141 using a wavelength selective device, e.g. a grating or etalon H01S5/146 takes precedence
• CPC Class Codes: H01S 5/146 using a fiber as external cavity

Abstract

A laser system for a spectroscopic catheter system utilizes an overmoded cavity in order to reduce mode hoping induced power fluctuations during wavelength scanning. In the preferred embodiment, a semiconductor gain medium is used to reduce cost. A fiber pigtail is used to define the laser cavity, which has a tight cavity mode spacing of less that 15 Gigahertz. A diffraction grating is used as the tuning element. A cylindrical lens is used to reduce alignment tolerances and thereby increase manufacturability.

Claims

1. A spectroscopic catheter system, comprising:

a catheter for insertion into a patient to transmit light to the patient;

a tunable laser source having a laser cavity including;

a wavelength selector for scanning a passband over a scan band,

a laser gain chip providing gain to modes of the laser cavity within a gain bandwidth provided by the passband;

wherein the laser cavity is characterized by a cavity mode spacing that is two or more times smaller than the gain bandwidth and two or more longitudinal modes of the laser cavity are lasing at all times during the scanning of the passband over the scan band, and

an output coupler for coupling laser light from laser cavity into the catheter; and

at least one detector for detecting light returning from the patient to perform spectroscopic analysis.

2. A catheter system as claimed in claim 1, wherein the catheter is inserted into a lumen of the patient.

3. A catheter system as claimed in claim 1, wherein the catheter is inserted into a blood vessel of the patient.

4. A catheter system as claimed in claim 1, wherein the catheter is inserted into a blood vessel to a heart of the patient.

5. A catheter system as claimed in claim 1, wherein the wavelength selector comprises a diffraction grating.

6. A catheter system as claimed in claim 1, wherein the wavelength selector comprises a bulk diffraction grating.

7. A catheter system as claimed in claim 1, wherein the wavelength selector comprises a Bragg grating.

8. A catheter system as claimed in claim 1, wherein the laser cavity further comprises an optical fiber pigtail coupling the laser gain chip and the wavelength selector.

9. A catheter system as claimed in claim 1, wherein the laser gain chip comprises a semiconductor optical amplifier.

10. A catheter system as claimed in claim 1, wherein the laser gain chip comprises a reflective semiconductor optical amplifier.

11. A catheter system as claimed in claim 1, wherein an optical length of the laser cavity is greater than 10 centimeters.

12. A catheter system as claimed in claim 1, wherein an optical length of the laser cavity is greater than 50 centimeters.

13. A catheter system as claimed in claim 1, wherein an optical length of the laser cavity is greater than 1 meter.

14. A catheter system as claimed in claim 1, wherein the cavity mode spacing is less than 15 Gigahertz.

15. A catheter system as claimed in claim 1, wherein the cavity mode spacing is less than 1.5 Gigahertz.

16. A catheter system as claimed in claim 1, wherein the gain bandwidth is greater than 10 Gigahertz.

17. A catheter system as claimed in claim 1, wherein the gain bandwidth is greater than 50 Gigahertz.

18. A catheter system as claimed in claim 1, wherein the gain bandwidth is greater than 100 Gigahertz.

19. A catheter system as claimed in claim 1, further comprising at least two laser gain chips.

20. A catheter system as claimed in claim 1, wherein the laser gain chip is contained within a pigtailed hermetic package.

21. A method for providing tunable frequency light to a patient, the method comprising:

inserting a catheter into a patient;

generating light with a tunable laser comprising a laser gain chip that provides gain to laser cavity modes within a passband of a wavelength selector in a laser cavity of the tunable laser;

tuning a frequency of the light across a scan band by scanning the passband of the wavelength selector over the scan band;

selecting a length of the laser cavity of the tunable laser so that a cavity mode spacing of the laser cavity modes is two or more times smaller than a gain bandwidth of the laser cavity and two or more longitudinal modes of the laser cavity are lasing at all times during the step of tuning the frequency of the light across the scan band; and

detecting light returning from the patient to determine a spectral response of tissue within the patient over the scan band.

22. A method as claimed in claim 21, wherein the step of selecting the length of the laser cavity comprises selecting the length so that ten or more longitudinal modes of the laser cavity are lasing at all times during the step of tuning the frequency of the light across the scan band.