Grafted network incorporating a multiple channel fluid flow connector

• US 6,986,751 B2
• Filed: 10/31/2003
• Issued: 01/17/2006
• Est. Priority Date: 08/05/2003
• Status: Expired due to Fees

• Current Assignee: Kips Bay Medical, Inc.
• Original Assignee: Cabg Medical, Inc.
• Inventors: Fletcher, Bruce, Villafana, Manuel A., Palmquist, William E.
• Primary Examiner(s): Bianco, Patricia
• Application Number:
  US10/698,253
• Publication Number:
  US 20050033218A1
• Time in Patent Office: 809 Days
• Field of Search: 604/4.01, 604/6.16, 604 7- 9, 604/264, 604/523, 604/533, 604/532, 604/537, 604/538, 604/905, 604/284, 604/317, 604/322, 604/326, 128/898, 606/1, 606/8, 606/108, 606/151, 606/153, 606155-158, 251/12, 251/24, 251/142, 251/148, 251/149, 251151-155, 403/169, 403/170, 403/220, 403/265
• US Class Current: 604/9
• CPC Class Codes: A61F 2/064 with special features to facilitate anastomotic coupling anastomosis of natural blood vessels A61B17/11

Abstract

A grafted network including one or more graft segments for use in coronary bypass procedures and which are configured to operably transport bypass blood flow from a singular supply location to one or more delivery locations in the grafted network is provided in combination with one or more multiple channel blood flow connectors for directing such bypass blood flow in the grafted network to one or more vascular members requiring restorative blood flow thereto. The grafted network also preferably includes one or more devices for operably maintaining the grafted network under relatively high internal fluid pressure so as to continuously supply selective vascular members with adequate bypass blood flow.

Claims

1. In combination with one or more graft segments configured to operably transport bypass blood flow from a singular supply location to one or more delivery locations in a grafted network, an apparatus for directing such bypass blood flow in said grafted network to one or more vascular members, said apparatus comprising:

a multiple channel blood flow connector for coupling at least a first graft segment to a first vascular member comprising a first blood flow delivery location, said flow connector including a supply conduit and a delivery conduit integrally formed therewith and adjacently disposed with respect to one another, with said supply conduit and said delivery conduit each having distinct lumen formed therewithin, said supply conduit having a first open end being operably coupled to a first respective open end of such first graft segment, said supply lumen and said delivery lumen being fluidly connected to one another through cooperating apertures in respective outer walls of said supply conduit and said delivery conduit at an intersection therebetween so as to provide for immediate bypass blood flow from said supply lumen to said delivery lumen, said delivery conduit having at least a first open end portion extending from said intersection and beyond a first perpendicular tangential plane of said supply conduit outer wall at a lateral side thereof with respect to said intersection, such that a first open end of said delivery conduit is laterally spaced from said supply conduit outer wall, an outer wall of said delivery conduit being formed at said first open end substantially along a plane in angular relationship with a plane parallel to a perpendicular cross-section of said delivery lumen, such angular relationship being between about 10 degrees and about 80 degrees therebetween, said first open end of said delivery conduit being configured for operable implantation directly into the first vascular member so as to provide bypass blood flow thereto, said delivery conduit being specifically sized to provide internal structural support for the first vascular member when said delivery conduit is implanted therein.

2. An apparatus as in claim 1 wherein the first graft segment is operably coupled to the blood flow supply location and said first open end of said supply conduit of said flow connector, and a first end of a second graft segment is operably coupled to a second open end of said supply conduit of said flow connector.

3. An apparatus as in claim 2, including a flow restricting means disposed downstream from said flow connector and operably coupled to said grafted network adjacent a terminal delivery location thereof opposite the supply location.

4. An apparatus as in claim 3 wherein said flow restricting means includes first and second open ends operably coupled to respective graft segments in said grafted network, with one of said respective graft segments extending between said flow restricting means and said terminal delivery location.

5. An apparatus as in claim 4 wherein said blood flow supply location is an aorta, and said terminal blood flow delivery location is an atrium or vena cava of a patient.

6. An apparatus as in claim 3, including one or more biocompatible coatings disposed on at least inner surfaces of said flow restricting means.

7. An apparatus as in claim 6 wherein at least one of said biocompatible coatings comprises silane, polyvinylpyrrolidine, heparin, and a photo-reactive cross-linking agent.

8. An apparatus as in claim 1, including one or more biocompatible coatings on at least inner surfaces of said flow connector.

9. An apparatus as in claim 8 wherein at least one of said biocompatible coatings comprises silane, polyvinylpyrrolidine, heparin, and a photo-reactive cross-linking agent.

10. An apparatus as in claim 1 wherein said delivery conduit includes a second end portion having a second end, with said second end portion extending from said intersection in a direction divergent from said first end portion of said delivery conduit.

11. An apparatus as in claim 10 wherein said first end of said delivery conduit is open, and said second end is closed.

12. An Apparatus as in claim 1 wherein said first open end of said supply conduit is tapered such that the thickness of said supply conduit outer wall at said first open end is less than about 50% of the thickness of said supply conduit outer wall at locations between said first open end and said intersection.

13. An apparatus as in claim 1 wherein at least said first open end of said delivery conduit is tapered such that the thickness of said delivery conduit outer wall at said first open end is less than about 50% of the thickness of said delivery conduit outer wall at locations between said first open end and said intersection.

14. An apparatus as in claim 1 wherein said cooperating apertures have radiused edges.

15. An apparatus as in claim 1, including a biocompatible coating disposed on at least inner surfaces of selected graft segments.

16. An apparatus as in claim 1 wherein said supply conduit has an external diameter of up to about 8 mm and said delivery conduit has an external diameter of up to about 5 mm.

17. An apparatus as in claim 1 wherein said first end portion of said delivery conduit is at least 1 mm longer than said second end portion of said delivery conduit as measured from said intersection.

18. An apparatus as in claim 1 wherein at least said delivery conduit is formed from a selectively expansive material for providing an interference fit between said delivery conduit and the vascular members sufficient to assist in forming a liquid-tight seal therebetween.