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Polyanionic polymers which enhance fusogenicity

  • US 6,986,902 B1
  • Filed: 04/27/1999
  • Issued: 01/17/2006
  • Est. Priority Date: 04/28/1998
  • Status: Expired due to Fees
First Claim
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1. A compound of the formula embedded imagewherein:

  • R1 is a member selected from the group consisting of hydrogen, hydroxyl, amino, optionally-substituted alkyl and a ligand;

    Y is a member selected from the group consisting of hydrogen, optionally-substituted alkyl, optionally-substituted cycloalkyl, optionally-substituted aryl and optionally-substituted heteroaryl;

    X is a member selected from the group consisting of optionally-substituted amino, oxygen, sulfur and a carbon single bond;

    R2 is a member selected from the group consisting of C6

    C26 alkyl, C6

    C26 alkenyl, dialkylglycerolyl, dialkenylglycerolyl, diacylglycerolyl, 1,2-diacyl-sn-glycero-3-phosphoethylenyl, 1,2-dialkoxy-3-aminopropanyl and 1,2-diacyloxy-3-aminopropanyl;

    R3 is a member selected from the group consisting of hydrogen, hydroxyl, amino, optionally-substituted alkyl and a ligand;

    n is greater than 1; and

    i is greater than 1.

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