Container for holding cells or viruses for disruption
First Claim
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1. A container for use with an ultrasonic transducer to disrupt cells or viruses, the container comprising:
- a) a chamber for holding the cells or viruses, the chamber being defined by two spaced apart, opposing major walls and side walls connecting the major walls to each other, wherein at least one of the major walls;
(i) has an external surface to which the transducer may be coupled; and
(ii) is sufficiently flexible to flex in response to vibratory motion of the transducer;
b) a port for introducing the cells or viruses into the chamber;
c) a channel connecting the port to the chamber;
d) a plunger that is inserted into the channel to increase pressure in the chamber; and
e) beads in the chamber.
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Abstract
A container for holding cells or viruses for disruption comprises a chamber defined by two spaced apart, opposing major walls and side walls connecting the major walls to each other. At least one of the major walls has an external surface to which the transducer may be coupled and is sufficiently flexible to flex in response to vibratory motion of the transducer. The container also has at least one port for introducing the cells or viruses into the chamber. In some embodiments, the chamber contains beads for aiding the disruption of the cells or viruses.
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Citations
11 Claims
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1. A container for use with an ultrasonic transducer to disrupt cells or viruses, the container comprising:
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a) a chamber for holding the cells or viruses, the chamber being defined by two spaced apart, opposing major walls and side walls connecting the major walls to each other, wherein at least one of the major walls; (i) has an external surface to which the transducer may be coupled; and (ii) is sufficiently flexible to flex in response to vibratory motion of the transducer; b) a port for introducing the cells or viruses into the chamber; c) a channel connecting the port to the chamber; d) a plunger that is inserted into the channel to increase pressure in the chamber; and e) beads in the chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification