Miniaturized high-density multichannel electrode array for long-term neuronal recordings
First Claim
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1. A real time closed loop brain-machine interface comprising:
- (a) a multichannel microwire electrode array for acquiring neural signals from a plurality of single neurons comprising;
(i) a plurality of microwire electrodes;
(ii) one or more printed circuit boards in electrical connection with the microwire electrodes comprising;
(1) a plurality of conductive traces spaced apart about 0.015 inches (center to center) or less; and
(2) a plurality of conductive pads in electrical connection with the one or more conductive traces; and
(iii) one or more connectors in communication with conductive pads and having contacts spaced apart about 0.030 inches (center to center) or less;
(b) a signal processing mechanism adapted to communicate with the multichannel microwire electrode array and adapted to form extracted motor commands from the extracellular electrical signals; and
(c) an actuator adapted to communicate with the signal processing mechanism and to respond to the extracted motor commands by effecting a movement, and to provide sensory feedback to the subject.
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Abstract
A high-density multichannel microwire electrode array is disclosed. The array can comprise a variable number of electrodes. A method of assembling the array is further disclosed. Additionally, a plurality of devices employing the array are disclosed, including an intelligent brain pacemaker and a closed loop brain machine interface.
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11 Claims
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1. A real time closed loop brain-machine interface comprising:
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(a) a multichannel microwire electrode array for acquiring neural signals from a plurality of single neurons comprising; (i) a plurality of microwire electrodes; (ii) one or more printed circuit boards in electrical connection with the microwire electrodes comprising; (1) a plurality of conductive traces spaced apart about 0.015 inches (center to center) or less; and (2) a plurality of conductive pads in electrical connection with the one or more conductive traces; and (iii) one or more connectors in communication with conductive pads and having contacts spaced apart about 0.030 inches (center to center) or less; (b) a signal processing mechanism adapted to communicate with the multichannel microwire electrode array and adapted to form extracted motor commands from the extracellular electrical signals; and (c) an actuator adapted to communicate with the signal processing mechanism and to respond to the extracted motor commands by effecting a movement, and to provide sensory feedback to the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification