Medical system, method and apparatus employing MEMS
First Claim
1. A biological suspension processing system comprising:
- a blood treatment device for treating one or more components of a biological suspension;
a human subject;
a first fluid flow path, wherein said first fluid flow path is in continuing, direct communication with the vascular system of the human subject and the treatment device for introducing blood from the human subject into the treatment device;
a second fluid flow path communicating with the treatment device for withdrawing a constituent of the blood from the treatment device;
a third fluid flow path communicating with the treatment device for withdrawing another constituent of the blood from the treatment device;
at least one microelectromechanical sensor communicating with one of said fluid flow paths for sensing either a biological or a chemical characteristic of the fluid within the flow path while said first fluid flow path is in continuing, direct communication with the vascular system of the human subject and a controller adapted to receive signals from said sensor and control the blood treatment device in response thereto.
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Accused Products
Abstract
A biological suspension processing system is disclosed that may include a suspension treatment device for treating one or more components of a biological suspension, a first fluid flow path for introducing a suspension into the treatment device and a second fluid flow path for withdrawing a constituent of the suspension from the device. At least on microelectromechanical (MEM) sensor communicates with one of the fluid flow paths for sensing a selected characteristic of the fluid therewith. The MEM sensor may be located elsewhere, such as on a container or bag and communicate with the interior for sensing a characteristic of the fluid contained therein. A wide variety of characteristics may be sensed, such as flow rate, pH, cell type, cell antigenicity, DNA, viral or bacterial presence, cholesterol, hematocrit, cell concentration, cell count, partial pressure, pathogen presence, or viscosity.
118 Citations
48 Claims
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1. A biological suspension processing system comprising:
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a blood treatment device for treating one or more components of a biological suspension;
a human subject;
a first fluid flow path, wherein said first fluid flow path is in continuing, direct communication with the vascular system of the human subject and the treatment device for introducing blood from the human subject into the treatment device;
a second fluid flow path communicating with the treatment device for withdrawing a constituent of the blood from the treatment device;
a third fluid flow path communicating with the treatment device for withdrawing another constituent of the blood from the treatment device;
at least one microelectromechanical sensor communicating with one of said fluid flow paths for sensing either a biological or a chemical characteristic of the fluid within the flow path while said first fluid flow path is in continuing, direct communication with the vascular system of the human subject and a controller adapted to receive signals from said sensor and control the blood treatment device in response thereto. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A biological suspension processing system comprising:
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a blood treatment device for treating one or more components of a biological suspension;
a human subject;
a first fluid flow path, wherein said first fluid flow path is in continuing, direct communication with the vascular system of the human subject and the treatment device for introducing blood from the human subject into the treatment device;
a first microelectromechanical sensor communicating with said first fluid flow path for sensing an initial condition of the fluid within said first fluid flow path while said first fluid flow path is in continuing, direct communication with the vascular system of the human subject, said first sensor further generating a signal responsive to the initial condition of the fluid in said first fluid flow path;
a second fluid flow path communicating with the treatment device for withdrawing a constituent of the blood from the treatment device;
a second microelectromechanical sensor communicating with said second fluid flow path for sensing either an in-process condition or a final product condition of the fluid within said second fluid flow path while said first fluid flow path is in continuing, direct communication with the vascular system of the human subject, said second sensor further generating a signal responsive to the in-process condition or final condition of the fluid in said second fluid flow path; and
a controller adapted to receive the first and second sensor signals and to control the treatment device in response thereto. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39)
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40. A biological suspension processing system comprising:
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a blood treatment device for treating one or more components of a biological suspension;
a human subject;
a first fluid flow path, wherein said first fluid flow path is in continuing, direct communication with the vascular system of the human subject and the treatment device for introducing blood from the human subject into the treatment device;
a first microelectromechanical sensor communicating with said first fluid flow path for sensing an initial condition of the fluid within said first fluid flow path while said first fluid flow path is in continuing, direct communication with the vascular system of the human subject, said first sensor further generating a signal responsive to the initial condition of the fluid in said first fluid flow path;
a second fluid flow path communicating with the treatment device for withdrawing a constituent of the blood from the treatment device;
a second microelectromechanical sensor communicating with said second fluid flow path for sensing either an in-process condition or a final product condition of the fluid within said second fluid flow path while said first fluid flow path is in continuing, direct communication with the vascular system of the human subject, said second sensor further generating a signal responsive to the in-process condition of the fluid in said second fluid flow path;
a third fluid flow path communicating with the treatment device for withdrawing another constituent of the blood from the treatment device;
a third microelectromechanical sensor communicating with said third fluid flow path for sensing a final product condition of the fluid within said third fluid flow path while said first fluid flow path is in continuing, direct communication with the vascular system of the human subject, said third sensor further generating a signal responsive to the final product condition of the fluid in said third fluid flow path; and
a controller adapted to receive the first, second, and third sensor signals and to control the treatment device in response thereto. - View Dependent Claims (41, 42, 43, 44, 45, 46, 47, 48)
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Specification