Collection device for lateral flow chromatography
First Claim
1. A lateral flow device for analyzing analytes in a liquid, comprising:
- a collection member having a collection pad for absorbing or adsorbing a liquid to which the collection member is exposed;
a lateral flow member along which liquid moves from the collection member, the lateral flow member also including an indicator agent that indicates an absence, presence and/or amount of the analyte; and
a removable barrier located between the collection member and the lateral flow member that inhibits the flow of liquid from the collection member when the removable barrier is present;
wherein said barrier is removed from between the collection member and the lateral flow member to allow liquid to move therebetween.
5 Assignments
0 Petitions
Accused Products
Abstract
A device for collecting oral liquids includes a lateral flow chromatography strip having a collection pad for insertion into the mouth. The collection pad is separated from the remainder of the chromatography strip by a liquid impermeable removable barrier which prevents liquid in the collection pad from entering the chromatography strip. Once adequate oral liquid has been collected (as indicated by a sample sufficiency indicator), the device is withdrawn from the mouth and the barrier is removed to allow oral liquids to flow through the strip. The liquids interact with binding partners in the strip to provide test results, such as an indication that an analyte of interest is present in the liquid. The strip may be contained in a housing with an access opening through which the removable barrier may be manipulated, and windows through which test results may be viewed. This device avoids reflux of reagents from the strip into the mouth of a test subject during use.
89 Citations
21 Claims
-
1. A lateral flow device for analyzing analytes in a liquid, comprising:
-
a collection member having a collection pad for absorbing or adsorbing a liquid to which the collection member is exposed; a lateral flow member along which liquid moves from the collection member, the lateral flow member also including an indicator agent that indicates an absence, presence and/or amount of the analyte; and a removable barrier located between the collection member and the lateral flow member that inhibits the flow of liquid from the collection member when the removable barrier is present; wherein said barrier is removed from between the collection member and the lateral flow member to allow liquid to move therebetween. - View Dependent Claims (2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
-
-
3. A lateral flow device for analyzing analytes in a liquid, comprising:
-
a collection member for absorbing or adsorbing a liquid to which the collection member is exposed; a lateral flow member along which liquid moves from the collection member, the lateral flow member also including an indicator agent that indicates an absence, presence and/or amount of the analyte; and a removable barrier between the collection member and the lateral flow member that inhibits the flow of liquid from the collection member when the removable barrier is present, wherein the collection member overlaps the lateral flow member, and the removable barrier is a removable spacer interposed between the collection member and the lateral flow member.
-
Specification