Arteriosclerosis detection system

• US 6,999,812 B2
• Filed: 05/03/2002
• Issued: 02/14/2006
• Est. Priority Date: 10/22/1999
• Status: Expired due to Fees

• Current Assignee: BML Incorporated, Reiji Kawada
• Original Assignee: BML Incorporated, Reiji Kawada
• Inventors: Takano, Syoichi, Kawada, Reiji
• Primary Examiner(s): Imam, Ali
• Assistant Examiner(s): Roy, Baisakhi
• Application Number:
  US10/137,283
• Publication Number:
  US 20030009107A1
• Time in Patent Office: 1,383 Days
• Field of Search: 600/407, 600/434, 600/504, 600/561, 600/483, 600/457, 600/476, 600/480, 600/481, 600/482, 600/485, 600/479, 382/128, 351/221, 333/157
• US Class Current: 600/479
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/355 Detecting T-waves

Abstract

An arteriosclerosis detection system including an electrocardiographic signal detection device, an eyeground image detection device for detecting an eyeground image in synchronization with an electrocardiographic signal detected by the detection device. The arteriosclerosis detection system further includes an eyeground vein constriction detection device for detecting the constriction of an eyeground vein in the vicinity of a site at which the eyeground vein and an eyeground artery cross each other. The constriction is detected based on the detected eyeground image in synchronization with the electrocardiographic signal. The arteriosclerosis detection system detects the eyeground image by executing an algorithm of software, which provides an eyeground image synchronized with an electrocardiographic signal by obtaining a stationary eyeground image synchronized with an arbitrary electrocardiographic signal from an animated eyeground image.

Claims

1. An arteriosclerosis detection system comprising:

electrocardiographic signal detection means for detecting an electrocardiographic signal;

eyeground image detection means for continuously or discontinuously detecting an eyeground image in synchronization with the detected electrocardiographic signal; and

eyeground vein constriction detection means for detecting constriction of an eyeground vein by using a ratio of an outer diameter of the eyeground vein in a vicinity of a site at which the eyeground vein and an eyeground artery cross each other to a portion of the eyeground vein distant from the crossing site,

wherein the system is operable to detect the constriction on the basis of the eyeground image detected in synchronization with the electrocardiographic signal.

2. The arteriosclerosis detection system according to claim 1, wherein the electrocardiographic signal comprises at least one of an electrocardiographic R wave and T wave.

3. The arteriosclerosis detection system according to claim 1, wherein arteriosclerosis is detected by employment, as an arteriosclerosis index, of a degree of the constriction of an eye ground vein in a vicinity of a crossing site of an eyeground artery and the eyeground vein, the constriction degree being obtained using the eyeground image detection means.

4. The arteriosclerosis detection system according to claim 1, wherein the system is operable to detect a degree of aging of an artery of the subject by correlating normalized data obtained by normalizing, in accordance with the ages of a plurality of subjects, a degree of the constriction of an eyeground vein in a vicinity of a crossing site of an eyeground artery and the eyeground vein, the constriction degree being obtained using the arteriosclerosis detection system, with the degree of the constriction of each of the subjects.

14. The arteriosclerosis detection system according to claim 1, wherein the ratio is corrected by a correction value obtained from attributes of an intersection of the eyeground vein and the eyeground artery, and wherein based on the constriction of the vein arteriosclerosis is detected.

5. An arteriosclerosis detection system comprising:

electrocardiographic signal detection means for detecting an electrocardiographic signal;

eyeground image detection means for continuously or discontinuously detecting an eyeground image in synchronization with an electrocardiographic signal detected by the detection means; and

eyeground vein constriction detection means for detecting the constriction of an eyeground vein by using a ratio of an outer diameter of the eyeground vein in the vicinity of a site at which the eyeground vein and an eyeground artery cross each other to a portion of a eyeground vein distant from the crossing site,

wherein the system is operable to detect the constriction of the eyeground vein based on the eyeground image detected in synchronization with the electrocardiographic signal, and

wherein the system is operable to detect the eyeground image using software which can provide an eyeground image synchronized with an electrocardiographic signal by obtaining, by use of a computer, a stationary eyeground image synchronized with an arbitrary electrocardiographic signal from an animated eyeground image.

6. The arteriosclerosis detection system according to claim 5, wherein the software is configured to extract an eyeground image that is synchronized with an arbitrary electrocardiographic signal while displaying animated images of the eyeground and electrocardiogram on display means of a computer terminal.

7. The arteriosclerosis detection system according to claim 5, wherein the electrocardiographic signal comprises at least one of an electrocardiographic R wave and T wave.

8. The arteriosclerosis detection system according to claim 5, wherein the software is configured to detect arteriosclerosis using means for calculating a degree of the constriction of the eyeground vein in a vicinity of a crossing site of an eyeground artery and the eyeground vein, and for correlating, the calculated value obtained through the calculation with the degree of arteriosclerosis.

9. The arteriosclerosis detection system according to claim 8, wherein the calculated value is a consolidated value of calculation values obtained for different electrocardiographic signals.

10. The arteriosclerosis detection system according to claim 8, wherein the calculated value is a consolidated value of calculation values obtained from eyeground images of two or more portions, each portion corresponding to a crossing site or its vicinity of an eyeground artery and an eyeground vein.

11. The arteriosclerosis detection system according to claim 8, wherein the software is provided with means for calculating the rate of change in calculation values corresponding to different electrocardiographic signals.

12. The arteriosclerosis detection system according to claim 8, wherein the software is provided with means for correlating the rate of change in calculation values and elasticity of the artery for the detection of arteriosclerosis.

13. The arteriosclerosis detection system according to claim 8, further comprising:

a computer-readable medium having an algorithm evaluating the degree of arterial aging of the subject,

wherein the algorithm correlates normalized data obtained by normalizing, in accordance with the ages of a plurality of subjects, calculated values in relation to the degree of constriction of an eyeground vein in the vicinity of the crossing site of the eyeground artery and the eyeground vein, the constriction degree being obtained using the arteriosclerosis detection system, with calculated values in relation to the degree of constriction of each of the subjects.

15. The arteriosclerosis detection system according to claim 5, wherein the ratio is corrected by a correction value obtained from attributes of an intersection of the eyeground vein and the eyeground artery.

16. A method of detecting arteriosclerosis, the method comprising:

detecting an electrocardiographic signal;

continuously or discontinuously detecting an eyeground image in synchronization with the detected electrocardiographic signal; and

detecting constriction of an eyeground vein by using a ratio of an outer diameter of the eyeground vein in a vicinity of a site at which the eyeground vein and an eyeground artery across each other to a portion of the eyeground vein distant from the crossing site,

wherein the constriction being detected on basis of the eyeground image detected in synchronization with the electrocardiographic signal.