Human semaphorin proteins and polynucleotides encoding the same

• US 7,001,763 B1
• Filed: 10/17/2001
• Issued: 02/21/2006
• Est. Priority Date: 10/17/2000
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Scoville, John, Walke, D. Wade
• Primary Examiner(s): Andres, Janet L.
• Assistant Examiner(s): Gucker, Stephen
• Application Number:
  US09/981,318
• Time in Patent Office: 1,588 Days
• Field of Search: 435/320.1, 435/325, 536/23.5
• US Class Current: 435/320.1
• CPC Class Codes: C07K 14/47 from mammals

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising a nucleotide sequence encoding the amino acid sequence drawn from the group consisting of SEQ ID NO:

16.

5. The isolated nucleic acid of claim 1, wherein said nucleotide sequence is that of SEQ ID NO:

15.

2. An isolated cDNA molecule comprising the nucleotide sequence of SEQ ID NO:

15.

3. An isolated cDNA molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence of SEQ ID NO;

16, and

(b) hybridizes to a nucleotide sequence that is the complement of SEQ ID NO;

15.

4. A recombinant expression vector comprising a nucleotide sequence encoding the amino acid sequence of SEQ ID NO:

16.

6. The recombinant expression vector of claim 4, wherein said vector comprises the nucleotide sequence of SEQ ID NO:

15.

7. A cultured or isolated cell comprising the vector of claim 4.

8. The host cell of claim 7, wherein the nucleotide sequence is that of SEQ ID NO:

15.