Selective adherence of stent-graft coverings

• US 7,004,966 B2
• Filed: 04/09/2003
• Issued: 02/28/2006
• Est. Priority Date: 09/30/1998
• Status: Expired due to Term

• Current Assignee: Bard Peripheral Vascular Incorporated (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Randall, Scott L., Banas, Christopher E., Edwin, Tarun J., McCrea, Brendan
• Primary Examiner(s): TRUONG, KEVIN THAO
• Application Number:
  US10/410,589
• Publication Number:
  US 20030216805A1
• Time in Patent Office: 1,056 Days
• Field of Search: 623/1.13, 623/1.1, 623/1.19, 623/1.23, 623/1.16, 623/1.44, 606/194, 606/195, 606/198
• US Class Current: 623/1.13
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2240/001 Designing or manufacturing processes
• CPC Class Codes: A61F 2250/0003 having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 2250/0014 having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: B29C 65/02 by heating, with or without pressure
• CPC Class Codes: B29C 65/48 using adhesives , i.e. using supplementary joining material; solvent bonding
• CPC Class Codes: B29L 2031/753 Medical equipment; Accessories therefor bloodbags, medical bags B29L2031/7148; artificial eyes B29L2011/0008

Abstract

An endoluminal vascular device having a plurality of predetermined boding locations between respective first and second covering members to selectively encapsulate a support member. Selective bonding between the first and second covering members results in unbonded slip pockets to accommodate movement of the support member. Such a configuration allows compression of the support member with minimal force and also promotes a low profile of the compressed device. Unbonded regions of the covering members also encourage enhanced cellular penetration for rapid healing and can be configured to hold bioactive substances that diffuse through the covering members.

Claims

1. An endoluminal prosthesis, comprising:

at least one radially expandable support member, having a plurality of openings passing through a wall thereof, a main portion with a first outer diameter, and at least one flared end portion with a second outer diameter greater than the first outer diameter;

a first covering member comprising a biocompatible material, positioned about an interior surface of said support member; and

a second covering member comprising a biocompatible material, positioned about an exterior surface of said support member;

wherein said first covering member is bonded to said second covering member along two or more spaced apart bonding regions positioned in said openings in said support member, such that a pocket is formed between adjacent bonding regions, the pocket being sized greater than a thickness of the support member wall to permit movement of the support member wall within the pocket.

2. The endoluminal prosthesis according to claim 1, wherein said support member and said first and second covering members comprise a tubular configuration.

3. The endoluminal prosthesis according to claim 2, wherein said bonding regions are longitudinally oriented around the circumference of the first and second covering members.

4. The endoluminal prosthesis according to claim 2, wherein said bonding regions are circumferentially oriented along the longitudinal length of the first and second covering members.

5. The endoluminal prosthesis according to claim 1, wherein said first and second covering members comprises a length substantially equal to a length of the radially expandable support member.

6. The endoluminal prosthesis according to claim 1, wherein said first and second covering members comprise a length less then said radially expandable support member.

7. The endoluminal prosthesis according to claim 1, wherein at least one pocket contains a therapeutic drug.

8. The endoluminal prosthesis according to claim 1, wherein said first and second covering members are bonded at said bonding regions by an adhesive.

9. The endoluminal prosthesis according to claim 8, wherein said adhesive is selected from the group consisting essentially of an aqueous dispersion of polytetrafluoroethylene, a polytetrafluoroethylene tape, fluoroethylpolypropylene (FEP), or tetrafluoroethylene, and combinations thereof.

10. The endoluminal prosthesis according to claim 8, wherein said adhesive is initially in an unactivated state and is adapted to be activated through the use of either electromagnetic energy or ultraviolet energy.

11. The endoluminal prosthesis according to claim 1, wherein said first and second covering members are bonded at said bonding regions by a thermoplastic polymer.

12. The endoluminal prosthesis according to claim 11, wherein said thermoplastic polymer is selected from the group consisting essentially of polyethylene, polypropylene, polyurethane, or polyethylene terephthalate, and combinations thereof.

13. The endoluminal prosthesis according to claim 1, wherein said first and second covering members are bonded at said bonding regions through the application of heat.

14. The endoluminal prosthesis according to claim 1, wherein said radially expandable support member comprises a self-expanding stent.

15. The endoluminal prosthesis according to claim 1, wherein said biocompatible polymer material of said first and second covering members comprises expanded polytetrafluoroethylene.

16. The endoluminal prosthesis according to claim 1, wherein said radially expandable support member comprises a first diameter and a second diameter, said first diameter being greater than said second diameter, wherein said first covering member is bonded to said second covering member proximate said first diameter.

17. The endoluminal prosthesis according to claim 1, wherein end sections of said first and second covering members are fully bonded to one another through said openings in said support member.

18. An endoluminal prosthesis, comprising:

a first tubular structure comprising expanded polytetrafluoroethylene;

a second tubular structure comprising expanded polytetrafluoroethylene positioned concentrically about the first tubular structure, the first and second tubular structures having a length; and

at least one radially expandable support member positioned between the first and second tubular structures, the support member comprising a wall with openings passing therethrough,

wherein the length of the first and second tubular structures is less than a length of the radially expandable support member, and

wherein the first tubular structure is bonded to the second tubular structure along two or more spaced apart bonding regions positioned within the openings of the support member, the spacing of adjacent bonding regions resulting in a pocket that permits movement of the support member therewithin.

19. The endoluminal prosthesis according to claim 18, wherein said bonding regions are longitudinally oriented around the circumference of the first and second tubular structures.

20. The endoluminal prosthesis according to claim 18, wherein said bonding regions are circumferentially oriented along the longitudinal length of the first and second tubular structures.