Method and apparatus for correcting crosstalk and spatial resolution for multichannel imaging
First Claim
1. A multichannel imaging system for generating an ensemble of images from an object for each field of view of the object, wherein each image in the ensemble contains information from substantially only one source, comprising:
- (a) a collection lens disposed so that light traveling from the object passes through the collection lens and travels along a collection path;
(b) a dispersing component disposed in the collection path so as to receive the light that has passed through the collection lens, dispersing the light into a plurality of light beams, each light beam being directed away from the dispersing component in a different predetermined direction;
(c) an imaging lens disposed to receive the light beams from the dispersing component, thereby producing said ensemble of images, each image being produced from a different one of the light beams and being projected by the imaging lens toward a different predetermined location;
(d) a multichannel detector disposed to receive the plurality of images produced by the imaging lens, the multichannel detector producing a plurality of output signals, such that a separate output signal is produced for each of said light beams; and
(e) means for processing the output signals to;
(i) correct the output signals for any misalignment between the images in the ensemble on the multichannel detector to within sub-pixel resolution; and
(ii) reduce contributions from the output signals of other channels, to the output signal in each channel.
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Accused Products
Abstract
A multichannel imaging system generates an ensemble of images for each field of view of an object. Each image in the ensemble is intended to contain information from only one source among a plurality of sources for the object. However, due to crosstalk, at least a portion of the signal from a first source appears in a channel intended for a second source. Because the accuracy of the correction will be degraded if the images in an ensemble are spatially misaligned with respect to one another, the spatial offset between images is determined and a correction is applied to substantially eliminate the offset. Then, a correction to the signals is determined to substantially reduce the contributions to the signal in a channel from the signals in other channels. The signal processing can be employed to process the output signals for each of a plurality of different disclosed imaging systems.
120 Citations
16 Claims
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1. A multichannel imaging system for generating an ensemble of images from an object for each field of view of the object, wherein each image in the ensemble contains information from substantially only one source, comprising:
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(a) a collection lens disposed so that light traveling from the object passes through the collection lens and travels along a collection path;
(b) a dispersing component disposed in the collection path so as to receive the light that has passed through the collection lens, dispersing the light into a plurality of light beams, each light beam being directed away from the dispersing component in a different predetermined direction;
(c) an imaging lens disposed to receive the light beams from the dispersing component, thereby producing said ensemble of images, each image being produced from a different one of the light beams and being projected by the imaging lens toward a different predetermined location;
(d) a multichannel detector disposed to receive the plurality of images produced by the imaging lens, the multichannel detector producing a plurality of output signals, such that a separate output signal is produced for each of said light beams; and
(e) means for processing the output signals to;
(i) correct the output signals for any misalignment between the images in the ensemble on the multichannel detector to within sub-pixel resolution; and
(ii) reduce contributions from the output signals of other channels, to the output signal in each channel.
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2. A multichannel imaging system for generating an ensemble of images from an object having a plurality of field of views, for each field of view of the object, wherein each image in the ensemble contains information from substantially only one source, comprising:
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(a) a collection lens disposed so that light traveling from the object passes through the collection lens and travels along a collection path;
(b) a dispersing component disposed in the collection path so as to receive the light that has passed through the collection lens, dispersing the light into a plurality of light beams, each light beam being directed away from the dispersing component in a different predetermined direction;
(c) an imaging lens disposed to receive the light beams from the dispersing component, thereby producing said ensemble of images, each image being produced from a different one of the light beams and being projected by the imaging lens toward a different predetermined location;
(d) a multichannel detector disposed to receive the plurality of images produced by the imaging lens, the multichannel detector producing a plurality of output signals, such that a separate output signal is produced for each of said light beams; and
(e) means for processing the output signals to;
(i) correct the output signals for any misalignment between the images in the ensemble on the multichannel detector; and
(ii) reduce contributions from the output signals of other channels, to the output signal in each channel. - View Dependent Claims (3, 4, 5)
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6. A multichannel imaging system for generating an ensemble of images of an object, wherein each image in the ensemble contains information from substantially only a single source from among a plurality of sources, comprising:
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(a) a first collection lens disposed so that light from the object passes through the first collection lens and travels along a first collection path;
(b) a first light dispersing element disposed in the first collection path so as to disperse the light that has passed through the first collection lens, producing a first source from among said plurality of sources;
(c) a first imaging lens disposed to receive light from the first source, producing a first image from the first source, said first image being a first one of said ensemble of images;
(d) a first detector disposed to receive said first image produced by the first imaging lens, and in response thereto, producing a first output signal;
(e) a second collection lens disposed so that light from the object passes through the second collection lens and travels along a second collection path different than the first collection path;
(f) a second light dispersing element disposed in the second collection path so as to disperse the light that has passed through the second collection lens, producing a second source from among said plurality of sources;
(g) a second imaging lens disposed to receive light from the second source, producing a second image from the second source, said second image comprising a second one of said ensemble of images;
(h) a second detector disposed to receive said second image produced by the second imaging lens, producing a second output signal; and
(i) means coupled to each detector, for processing the first and the second output signals to perform the following functions;
(i) correcting the output signals for misalignment between the images on the first and the second detector; and
(ii) substantially reducing contributions to each of the first and the second output signals from the other of the first and the second output signals. - View Dependent Claims (7, 8, 9, 10, 11)
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12. A multichannel imaging system for generating an ensemble of images of an object, wherein each image in the ensemble contains information from substantially only a single source from among a plurality of sources, comprising:
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(a) a collection lens disposed so that light traveling from the object passes through the collection lens and is focussed along a collection path;
(b) a dispersing component that receives the light from the collection lens and disperses the light into a plurality of light beams, as a function of a plurality of different discriminable characteristics of the light, each of said plurality of light beams corresponding to a different one of said plurality of sources;
(c) at least one pixilated detector;
(d) an imaging lens that focuses each of the plurality of light beams on said at least one pixilated detector, producing a respective image corresponding to a different one of the plurality of light beams, each image being one of said ensemble of images, said at least one pixilated detector providing an output signal for each respective image; and
(e) a signal processor coupled to receive the output signals from said at least one pixilated detector, said signal processor processing the output signals to;
(i) correct the output signals for any misalignment between the respective images on said at least one pixilated detector; and
(ii) substantially reducing crosstalk between the output signals. - View Dependent Claims (13, 14, 15, 16)
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Specification