Apparatus and method for the treatment of an upper airway flow limitation

• US 7,011,087 B1
• Filed: 04/26/2000
• Issued: 03/14/2006
• Est. Priority Date: 04/23/1999
• Status: Expired due to Term

• Current Assignee: Australian Centre For Advanced Medical Technology Pty Ltd.
• Original Assignee: Australian Centre For Advanced Medical Technology Pty Ltd.
• Inventors: Sullivan, Colin
• Primary Examiner(s): Lewis, Aaron J.
• Application Number:
  US09/959,303
• Time in Patent Office: 2,148 Days
• Field of Search: 128/204.18, 128/204.21, 128/204.23, 128/200.24, 600/529, 600/534
• US Class Current: 128/200.24
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/10 Electroencephalographic signals

Abstract

An apparatus and a method for the treatment of an upper airway flow limitation, the apparatus including a means to detect an interruption in an upper airway inspiratory flow rate of the patient and further including a treatment means which treats the upper airway flow limitation on detection of the interruption cycle.

Claims

1. An apparatus for the treatment of hypertension caused by pre-eclampsia, the apparatus including:

a measuring means for measuring airway vibrations in a patient, the measuring means being selected from the group consisting of a pressure detector comprising a piezoelectric transducer and an accelerometer comprising an integrated circuit containing a floating piezoelectric transducer, said pressure detector or accelerometer being positionable on or under a bed on which a patient sleeps;

an identification means which identifies those measured airway vibrations which are indicative of an upper airway flow limitation; and

a treatment means which treats the upper airway flow limitation in the patient upon detection of the upper airway flow limitation.

4. The apparatus of claim 1, 2 or 3 when used for the treatment of hypertension caused by pre-eclampsia.

5. The apparatus of claim 1, 2 or 3 wherein airway vibrations in the frequency range of about 0.2 to about 10 Hz are identified by the identification means as indicative of the upper airway flow limitation.

6. The apparatus of claim 1, 2 or 3 wherein airway vibrations in the frequency range of about 0.5 to about 5 Hz are identified by the identification means as indicative of the upper airway flow limitation.

7. The apparatus of claim 1, 2 or 3 wherein the identification means is capable of generating a signal representative of the breathing cycle of the patient.

8. The apparatus of claim 7 wherein the identification means includes a comparator means which compares the signal representative of the breathing cycle with a signal representative of the airway vibrations and produces an output signal representative of the comparison.

10. The apparatus of claim 1 or 9 wherein a further pressure detector or accelerometer is attached to the bed frame or incorporated into a pillow.

14. The apparatus of claim 1, 2 or 3 wherein the treatment means is a device which applies continuous positive airway pressure to the airway of the patient.

15. The apparatus of claim 1, claim 2 or claim 3 wherein the treatment means has two modes of treatment, a first treatment mode when the patient is awake and a second treatment mode when the patient is asleep.

16. The apparatus of claim 15 wherein, in the first treatment mode, a relatively minimally intrusive continuous positive airway pressure is delivered to the airway of the patient.

17. The apparatus of claim 15 wherein, in the second treatment mode, a relatively higher continuous positive airway pressure is delivered to the airway of the patient than in the first treatment mode, the continuous positive airway pressure being set so as to be sufficient to treat the upper airway flow limitation in the patient.

18. The apparatus of claim 15 wherein the treatment means further includes a sleep sensor which determines whether the patient is asleep or awake.

19. The apparatus of claim 18 wherein the sleep sensor emits a signal upon sensing whether the patient is asleep or upon sensing that the patient is awake.

20. The apparatus of claim 19 wherein the treatment means further includes a switching means and whereupon receiving the signal from the sleep sensor, the switching means causes the treatment means to switch from one treatment mode to the other treatment mode.

21. The apparatus of claim 18 wherein the sleep sensor senses that the patient is asleep when there is a reduced average airflow in the airway of the patient.

22. The apparatus of claim 21 wherein the sleep sensor further includes a movement detector which detects the respiration effort in the patient.

23. The apparatus of claim 22 wherein the sleep sensor senses that the patient is asleep when there is a reduced respiration effort in the patient.

24. The apparatus of claim 18 wherein the sleep sensor includes an electrocardiograph.

2. An apparatus for the treatment of hypertension caused by pre-eclampsia, the apparatus including:

a measuring means for measuring airway vibrations in a patient, the measuring means being selected from the group consisting of a pressure detector comprising a piezoelectric transducer and an accelerometer comprising an integrated circuit containing a floating piezoelectric transducer, said pressure detector or accelerometer being attachable to a hearing aid positionable in an ear of the patient;

an identification means which identifies those measured airway vibrations which are indicative of an upper airway flow limitation; and

a treatment means which treats the upper airway flow limitation in the patient upon detection of the upper airway flow limitation.

3. An apparatus for the treatment of hypertension caused by pre-eclampsia, the apparatus including:

a measuring means for measuring airway vibrations in a patient, the measuring means consisting of a pressure detector comprising a piezoelectric transducer comprising one or a plurality of sheets of piezoelectric plastics material;

an identification means which identifies those measured airway vibrations which are indicative of an upper airway flow limitation; and

a treatment means which treats the upper airway flow limitation in the patient upon detection of the upper airway flow limitation.

9. The apparatus of claim 3 wherein the piezoelectric transducer is placed on or under a bed on which a patient sleeps.

11. The apparatus of claim 9 wherein said one or a plurality of sheets of piezoelectric plastics material are formed from polyvinylidine fluoride or an analogue or family derivative thereof.

12. The apparatus of claim 3 or 11 wherein the piezoelectric plastics material is attached to a firm rubber or plastic backing sheet.

13. The apparatus of claim 3 or 11 wherein the pressure detector detects both sub-audible vibrations of the patient'"'"'s airway and low frequency movements of the breathing cycle of the patient.

25. A method of treating a patient for hypertension caused by pre-eclampsia, the method including:

measuring airway vibrations in the patient using a measuring means that is selected from the group consisting of a pressure detector comprising a piezoelectric transducer and an accelerometer comprising an integrated circuit containing a floating piezoelectric transducer, said pressure detector or accelerometer being positionable on or under a bed on which a patient sleeps;

identifying those measured airway vibrations which are indicative of an upper airway flow limitation; and

on identification, treating the upper airway flow limitation in the patient.

28. The method of claim 25, 26 or 27 wherein airway vibrations identified in the frequency range of about 0.2 to about 10 Hz are taken as indicative of the upper airway flow limitation.

29. The method of claim 25, 26 or 27 wherein airway vibrations identified in the frequency range of about 0.5 to about 5 Hz are taken as indicative of the upper airway flow limitation.

30. The method of claim 25, 26 or 27 further including a step of identifying movements indicative of the breathing cycle of the patient.

31. The method of claim 30 further including the step of comparing movements indicative of the breathing cycle with the measured airway vibrations.

32. The method of claim 25, 26 or 27 wherein the step of treating the upper airway flow limitation includes application of continuous positive airway pressure to the airway of the patient.

33. The method of claim 32 wherein the step of treating the patient is carried out in two modes, a first treatment mode when the patient is awake and a second treatment mode when the patient is asleep.

34. The method of claim 33 further including the step of determining whether the patient is asleep or awake.

35. The method of claim 34 further including the step of switching between the two modes of treatment upon determining whether the patient is asleep or awake.

36. The method of claim 35 wherein whether the patient is asleep or awake is determined by the average airflow in the airway of the patient and further wherein a reduced average airflow in the airway of the patient is taken as indicative that the patient is asleep.

37. The method of claim 36 wherein whether the patient is asleep or awake is determined by the respiration effort of the patient and further wherein a reduced respiration effort is taken as indicative that the patient is asleep.

38. The method of claim 34 wherein whether the patient is awake or asleep is determined by analysis of an electrocardiogram of the patient.

26. A method of treating a patient for hypertension caused by pre-eclampsia, the method including:

measuring airway vibrations in the patient using a measuring means that is selected from the group consisting of a pressure detector comprising a piezoelectric transducer and an accelerometer comprising an integrated circuit containing a floating piezoelectric transducer, said pressure detector or accelerometer being attachable to a hearing aid positionable in an ear of the patient;

identifying those measured airway vibrations which are indicative of an upper airway flow limitation; and

on identification, treating the upper airway flow limitation in the patient.

27. A method of treating a patient for hypertension caused by pre-eclampsia, the method including:

measuring airway vibrations in the patient using a measuring means consisting of a pressure detector comprising a piezoelectric transducer comprising one or a plurality of sheets of piezoelectric plastics material;

identifying those measured airway vibrations which are indicative of an upper airway flow limitation; and

on identification, treating the upper airway flow limitation in the patient.