Stent designed for the delivery of therapeutic substance or other agents

• US 7,014,654 B2
• Filed: 11/30/2001
• Issued: 03/21/2006
• Est. Priority Date: 11/30/2001
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Jansen, Lex P., Welsh, Greg P.
• Primary Examiner(s): HO, UYEN T
• Application Number:
  US09/999,279
• Publication Number:
  US 20030105511A1
• Time in Patent Office: 1,572 Days
• Field of Search: 623/1.15, 623/1.16, 623 142- 146, 606/194
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91525 within the whole structure different bands showing different meander characteristics, e.g. frequency or amplitude
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91566 connected trough to trough
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2250/0018 differing in elasticity, stiffness or compressibility
• CPC Class Codes: A61F 2250/0035 differing in release or diffusion time
• CPC Class Codes: A61F 2250/0036 differing in thickness
• CPC Class Codes: A61F 2250/0068 the pharmaceutical product being in a reservoir
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

A stent comprising a serpentine portion extending about the circumference of the stent, the serpentine portion having a first end and a second end, the serpentine portion having a plurality of turns at the first end and a plurality of turns at the second end and struts extending therebetween, at least one of the turns at the first end, at least one of the turns at the second end, at least one of the struts therebetween, or some combination thereof having a plurality of shaped recesses thereon.

Claims

1. A stent comprising a first strut having a first side and a second side, each side having alternating crests and troughs wherein the crests of said first side of said first strut align with the troughs of said second side of said first strut, said first strut having a second strut adjacent said first strut, having a first side and a second side, each side having alternating crests and troughs wherein the crests of said first side of said second strut align with said troughs of said second side of said second strut, and said crests of said first side of said first strut align with said crests of said second side of said second strut and said troughs of said first side of said first strut align with said troughs of said second side of said second strut, the stent further comprising at least one turn having at least one shaped recess.

2. The stent of claim 1 wherein said first strut has a wave-like pattern.

3. The stent of claim 1 wherein said second strut has a wave-like pattern.

4. The stent of claim 1 having at least one shaped recess located between at least one crest and trough of said first strut.

5. The stent of claim 1 having at least one shaped recess located between a crest and a trough of said first strut and at least one shaped recess located between a crest and a trough of said second strut.

6. The stent of claim 1 wherein said at least one shaped recess is an elongated ellipsoid.

7. The stent of claim 1 wherein said at least one shaped recess has a substantially circular shape.

8. The stent of claim 1 wherein said at least one shaped recess contains a therapeutic agent.

9. The stent of claim 8 wherein said therapeutic agent is selected from the group consisting of genetic material, growth factors, antineoplastics, antimitotics, anti-inflammatories, antiplatelets, anticoagulants, antifibrins, antithrombins, antiproliferatives, antibiotics, antioxidants, and antiallergenic substances.

10. The stent of claim 5 wherein the recess located between the crest and trough of said first strut and the recess located between the crest and trough of said second strut both contain a therapeutic agent.

11. The stent of claim 1 wherein a plurality of said struts have a plurality of shaped recesses thereon, and a plurality of turns have a plurality of shaped recesses thereon.

12. The stent of claim 1 having a plurality of shaped recesses having substantially circular and ellipsoid shapes.

13. The stent of claim 1 wherein at least one strut has more than one shaped recess thereon.