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Apparatus and method for non-invasively measuring cardiac output

  • US 7,018,340 B2
  • Filed: 09/08/2003
  • Issued: 03/28/2006
  • Est. Priority Date: 12/19/1996
  • Status: Expired due to Term
First Claim
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1. A method for estimating the cardiac output of an individual, comprising:

  • determining a carbon dioxide elimination (VCO2) of the individual for a before re-breathing period and for a during re-breathing period;

    calculating a carbon dioxide elimination difference between the carbon dioxide elimination of the before re-breathing period and the carbon dioxide elimination of the during re-breathing period;

    estimating a partial pressure of carbon dioxide in alveoli (PACO2) of the individual for the before re-breathing period and for the during re-breathing period based on partial pressure of end tidal carbon dioxide (PetCO2) measurements of the individual during the before re-breathing period and during the during re-breathing period, respectively;

    converting each estimation of the partial pressure of carbon dioxide in alveoli to a carbon dioxide content (CCO2);

    calculating a carbon dioxide content difference between the carbon dioxide content of the before re-breathing period and the carbon dioxide content of the during re-breathing period; and

    dividing the carbon dioxide elimination difference by the carbon dioxide content difference to estimate cardiac output.

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