Methods and apparatus for stroke patient treatment

• US 7,018,341 B2
• Filed: 12/11/2001
• Issued: 03/28/2006
• Est. Priority Date: 12/11/2000
• Status: Expired due to Term

• Current Assignee: ResMed Pty Ltd. (ResMed Incorporated)
• Original Assignee: Resmed Limited (ResMed Incorporated)
• Inventors: Ujhazy, Anthony John, Hansford, Alison Mary, Wright, Jonathan Caldwell
• Primary Examiner(s): Nasser, Robert L.
• Assistant Examiner(s): Natnithithadha, Navin
• Application Number:
  US10/450,068
• Publication Number:
  US 20040138576A1
• Time in Patent Office: 1,568 Days
• Field of Search: 600/529, 600531-533, 600537-539, 128/204.18, 128/204.21, 128/204.23
• US Class Current: 600/538
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61B 5/1135 by monitoring thoracic expansion
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61M 16/0066 Blowers or centrifugal pumps
• CPC Class Codes: A61M 16/0069 the speed thereof being controlled by respiratory parameters, e.g. by inhalation
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/085 Gas sampling
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)
• CPC Class Codes: A61M 2230/63 Motion, e.g. physical activity

Abstract

Methods and apparatus for assessing the condition of and treating patients for stroke during the delivery of continuous positive airway pressure (CPAP) are disclosed. By determining central and obstructive apnea occurrences or the percentile of pressure delivered to the patient from patient airflow, stroke indicators may be calculated and analyzed to provide information on the type of stroke a patient has suffered and the degree of a patient'"'"'s neuro-recovery. The apparatus may be programmed with a particular protocol intended to identify between alternative forms of CPAP treatment appropriate for the patient based upon an assessment of the patient'"'"'s condition. The device can select and recommend between the various treatment forms, identify billing reimbursement codes and generate data to track patient response to stroke treatments.

Claims

1. A method for evaluating the condition of a patient after stroke comprising the steps of:

delivering breathable gas at a pressure above atmospheric to a patient after stroke;

measuring the airflow of said patient; and

determining a stroke indicator from said airflow, said determining step including analyzing said airflow to determine occurrences of central apnea and occurrences of obstructive apnea,

wherein said stroke indicator is calculated as a function of a ratio of said occurrences of central apnea and said occurrences of obstructive apnea.

2. The method of claim 1 further comprising recording said stroke indicator over time.

3. The method of claim 2 further comprising the step of analyzing said stroke indicator over time to determine a change in said stroke indicator.

4. The method of claim 1 wherein said determining step includes analyzing said airflow to determine a first percentile pressure from pressure delivered to a patient in a current session and comparing said first percentile pressure with a second percentile pressure from pressure delivered to said patient in a prior session.

5. The method of claim 4 wherein said first and second percentile pressures are 95th percentile pressures.

6. The method of claim 3 or 5 wherein said stroke indicator indicates a degree of neuro-recovery of the patient.

7. The method of claim 1 wherein said stroke indicator indicates a type of stroke that the patient has suffered.

8. The method of claim 1 further comprising the step of recording said stroke indicator in a database of stroke indicators for multiple patients.

9. The method of claim 1 further comprising the step of identifying subsequent treatment based upon said stroke indicator.

10. The method of claim 9 wherein said treatment is a form of CPAP therapy.

11. The method of claim 9 wherein said treatment is a change in drug therapy.

12. A method for evaluating the condition of a patient after stroke comprising the steps of:

delivering breathable gas at a pressure above atmospheric to a patient after stroke;

measuring the airflow of said patient;

determining a stroke indicator from said airflow, said stroke indicator representing information about the patient'"'"'s condition, and

evaluating changes in said stroke indicator to assess the efficacy of an administered drug, said evaluating step including storing said stroke indicator in a database of patient information, said stroke indicator being a function of the number of occurrences of central apnea and the number of occurrences of obstructive apnea,

wherein said stroke indicator is a function of a ratio of said number of occurrences of central apnea and said number of occurrences of obstructive apnea.