Method and apparatus for monitoring cerebral physiology
First Claim
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1. A method of monitoring the cerebral cellular environment of a patient for prognosis and for providing information for treatment comprising:
- providing an opening in the skull of said patient;
inserting a catheter through said opening into a region of cerebrospinal fluid (CSF) within said skull of said patient, said catheter having a flow section capable of permitting said CSF to flow therein;
positioning said flow section of said catheter into said region of CSF;
placing at least one sensor capable of sensing pH into said flow section within said catheter to enable said CSF to flow adjacent said sensor so that said sensor may sense at least one characteristic, including pH, of said CSF;
monitoring changes of said at least one characteristic of said CSF within the initial 48 hours following head trauma; and
predicting the outcome of the head trauma based on the monitored changes.
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Abstract
A method and apparatus for predicting the outcome of head injury trauma by monitoring cerebrospinal fluid (CSF) characteristics, preferably my monitoring the pH of CSF. The apparatus includes a catheter with a wall section adapted to permit CSF to flow therein, and a sensor located within the catheter such that the CSF is permitted to flow adjacent the tip of the sensor.
21 Citations
29 Claims
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1. A method of monitoring the cerebral cellular environment of a patient for prognosis and for providing information for treatment comprising:
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providing an opening in the skull of said patient; inserting a catheter through said opening into a region of cerebrospinal fluid (CSF) within said skull of said patient, said catheter having a flow section capable of permitting said CSF to flow therein; positioning said flow section of said catheter into said region of CSF; placing at least one sensor capable of sensing pH into said flow section within said catheter to enable said CSF to flow adjacent said sensor so that said sensor may sense at least one characteristic, including pH, of said CSF; monitoring changes of said at least one characteristic of said CSF within the initial 48 hours following head trauma; and predicting the outcome of the head trauma based on the monitored changes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method of monitoring at least one characteristic of cerebrospinal fluid (CSF) of a patient for prognosis and for providing information for treatment comprising:
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providing an opening in the skull of said patient through which a region of CSF is accessible; inserting a catheter through said opening into said region of CSF in said patient, said catheter having a flow section capable of permitting said CSF to flow therein; positioning said flow section of said catheter into said region of CSF; placing at least one sensor capable of sensing pH into said flow section within said catheter to enable said CSF to flow adjacent said sensor so that said sensor may sense at least one characteristic, including pH, of said CSF; monitoring changes of said at least one characteristic of said CSF within the initial 48 hours following head trauma; and predicting the outcome of the head trauma based on the monitored changes. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19)
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20. An apparatus for monitoring the cerebral cellular environment of a patient, comprising:
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a catheter having a wall section adapted to permit cerebrospinal fluid (CSF) to flow therein, said catheter adapted for introduction through an opening in a skull of a patient; and at least one sensor capable of sensing pH located within a porous sheath, wherein said porous sheath is located within said catheter such that said CSF is permitted to flow through said porous sheath and adjacent said sensor; said sensor further being capable of monitoring at least one characteristic, including pH, of said CSF over time. - View Dependent Claims (21, 22, 23, 24)
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25. An apparatus for monitoring at least one characteristic of cerebrospinal fluid (CSF) of a patient, comprising:
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a catheter having a wall section adapted to permit said CSF to flow therein, said catheter adapted for introduction through an opening in said patient through which a region of CSF is accessible; and at least one sensor capable of sensing pH located within a porous sheath, wherein said porous sheath is located within said catheter such that said CSF is permitted to flow through said porous sheath and adjacent said sensor; said sensor further being capable of monitoring at least one characteristic, including pH, of CSF over time. - View Dependent Claims (26, 27, 28, 29)
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Specification