Metered dose delivery device for liquid and powder agents
First Claim
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1. A device for delivery of at least one dose of an agent comprising:
- a body member having at a first end a canister housing a propellant and a second end adapted for insertion into the mouth or nose of a user;
a container within the body member, for holding the dose of agent, wherein the container is positioned between the canister and second end; and
a mechanism for exposing the dose of agent in the container to the propellant, the mechanism positioned between the canister and the container;
whereby as the canister is moved towards the container, (i) the mechanism passes through the container thereby carrying the dose of agent towards the second end, and (ii) the canister is actuated to expel the propellant and the dose of agent from the mechanism into the mouth or nose of the user.
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Abstract
A delivery device for the delivery of an agent to the mouth, nose or other bodily site of a user. The delivery device includes an aerosol canister that is actuated to expel propellant, which captures and disperses the agent. In a preferred embodiment, the propellant captures and disperses the agent into the mouth or nose of a user, and inhalation by the user directs the agent to the lungs of the user. The delivery device is particularly suitable for the treatment of bronchial asthma, respiratory conditions and for the delivery of systemically absorbed agents.
63 Citations
46 Claims
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1. A device for delivery of at least one dose of an agent comprising:
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a body member having at a first end a canister housing a propellant and a second end adapted for insertion into the mouth or nose of a user; a container within the body member, for holding the dose of agent, wherein the container is positioned between the canister and second end; and a mechanism for exposing the dose of agent in the container to the propellant, the mechanism positioned between the canister and the container; whereby as the canister is moved towards the container, (i) the mechanism passes through the container thereby carrying the dose of agent towards the second end, and (ii) the canister is actuated to expel the propellant and the dose of agent from the mechanism into the mouth or nose of the user. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44)
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45. A method for the delivery of at least one dose of inhalable medicinal agents, the method comprising the steps of:
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(a) providing a device for delivery of a dose of the agent comprising; a body member having at a first end an aerosol canister housing a propellant and a second end for insertion into the mouth or nose of a user, the aerosol canister being movable downwards within the body member; and a container within the body member, for holding the dose of agent, positioned between the aerosol canister and second end; and a mechanism for exposing the dose of agent in the container to the propellant, the mechanism positioned between the canister and the container; (b) inserting the second end of the body member into the mouth or nose of the user; (c) actuating the aerosol canister to expel propellant through the body member towards the second end, by moving the aerosol canister towards the second end, whereby as the canister is moved towards the second end, the mechanism passes through the container thereby carrying the dose of the agent towards the second end; and (d) allowing the propellant to disperse the dose of agent from the mechanism into the mouth or nose of a user.
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46. A method for the delivery of at least one dose of inhalable medicinal agents by use of device for delivery of an agent, wherein the device comprises:
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(a) a body member having at a first end an aerosol canister housing a propellant and a second end for insertion into the mouth or nose of a user, the aerosol canister being movable downwards within the body member; (b) a container within the body member, for holding the dose of agent, positioned between the aerosol canister and second end; and (c) a mechanism for exposing the dose of agent in the container to the propellant, the mechanism being positioned between the canister and the container; wherein the method comprises; (i) inserting the second end of the body member into the mouth or nose of the user; (ii) actuating the aerosol canister to expel propellant through the body member towards the second end, by moving the aerosol canister towards the second end, whereby as the canister is moved towards the second end, the mechanism passes through the container, thereby carrying the dose of agent towards the second end; and (d) allowing the propellant to disperse the dose of agent from the mechanism into the mouth or nose of the user.
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Specification