Compositions and methods for body weight management

• US 7,025,984 B1
• Filed: 06/26/2000
• Issued: 04/11/2006
• Est. Priority Date: 06/26/2000
• Status: Expired due to Term

• Current Assignee: The Procter & Gamble Company
• Original Assignee: The Procter & Gamble Company
• Inventors: Jandacek, Ronald James, Kelm, Gary Robert, Bharaj, Satinder Singh, Penafiel, Jorge Villanueva
• Primary Examiner(s): Page, Thurman K.
• Assistant Examiner(s): Oh, Simon J.
• Application Number:
  US09/603,626
• Time in Patent Office: 2,115 Days
• Field of Search: 424/400, 424/439, 424/451, 424/464, 514/558
• US Class Current: 424/439
• CPC Class Codes: A23D 7/011 Compositions other than spreads
• CPC Class Codes: A23D 9/013 Other fatty acid esters, e.g. phosphatides
• CPC Class Codes: A23G 3/40 characterised by the fats used containing dairy products A23G3/46
• CPC Class Codes: A23K 20/158 Fatty acids; Fats; Products containing oils or fats
• CPC Class Codes: A23K 50/20 for horses
• CPC Class Codes: A23K 50/40 for carnivorous animals, e.g. cats or dogs
• CPC Class Codes: A23L 33/12 Fatty acids or derivatives thereof
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/332 Promoters of weight control and weight loss
• CPC Class Codes: A23V 2250/1876 Long-chain fatty acids
• CPC Class Codes: A23V 2250/1942 Long-chain triglycerides
• CPC Class Codes: A61K 31/20 having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
• CPC Class Codes: A61K 31/201 having one or two double bonds, e.g. oleic, linoleic acids
• CPC Class Codes: A61K 31/202 having three or more double bonds, e.g. linolenic eicosanoids, e.g. leukotrienes A61K31/557
• CPC Class Codes: A61K 31/23 of acids having a carboxyl group bound to a chain of seven or more carbon atoms
• CPC Class Codes: A61K 31/231 having one or two double bonds
• CPC Class Codes: A61K 31/232 having three or more double bonds, e.g. etretinate
• CPC Class Codes: A61P 3/04 Anorexiants; Antiobesity agents

Abstract

The present invention is for compositions and methods for managing the body weight of a subject using said compositions. Weight management, particularly weight gain and loss, is effectuated by producing a sensation of satiety in said subjects. The method of managing body weight includes administering the composition prior to food consumption, concurrent with food consumption, as replacement for food consumption and combinations thereof.

Claims

1. A method of managing body weight selected from the group consisting of inducing satiety, controlling appetite, and combinations thereof, comprising orally administering to a human or other animal subject a composition comprising from about 0.01 grams to about 10 grams, per kilogram of body weight of the subject, of ethyl oleate, wherein the ethyl oleate releases in the stomach of the subject.

2. The method according to claim 1 wherein from about 0.04 grams to about 1 gram, per kilogram of body weight of the subject, of the ethyl oleate is orally administered.

3. The method according to claim 2 wherein the oral administration is daily.

4. The method according to claim 2 wherein the oral administration replaces one or more of meals of the subject.

5. The method according to claim 2 wherein the oral administration is over the course of a weight management program.

6. The method according to claim 5 wherein the oral administration is concomitant with consumption of food by the subject.

7. The method according to claim 6 wherein the food has a triacylglycerol level of about 5 grams or less.

8. The method according to claim 2 wherein the oral administration is from about 30 minutes to about 6 hours prior to consumption of food by the subject.

9. The method according to claim 8 wherein the food has a triacylglycerol level about 5 grams or less.

10. The method according to claim 2 wherein the subject is a companion animal.

11. The method according to claim 2 wherein the subject is a human.

12. The method according to claim 11 wherein the composition is a beverage.

13. The method according to claim 12 wherein the beverage further comprises an ingredient selected from the group consisting of suspending agents, flavorants, viscosity modifiers, and mixtures thereof.

14. The method according to claim 12 wherein the beverage further comprises a nutrient selected from the group consisting of vitamins, minerals, and mixtures thereof.

15. The method according to claim 11 wherein the composition is a bar.

16. The method according to claim 11 wherein the composition is a dosage form selected from the group consisting of tablets and capsules.