Method and apparatus for affecting atrial defibrillation with bi-atrial pacing

• US 7,027,861 B2
• Filed: 10/09/2001
• Issued: 04/11/2006
• Est. Priority Date: 10/09/2001
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Thompson, David L.
• Primary Examiner(s): Pezzuto, Robert E.
• Assistant Examiner(s): DROESCH, KRISTEN L
• Application Number:
  US09/974,079
• Publication Number:
  US 20030069609A1
• Time in Patent Office: 1,645 Days
• Field of Search: 607/4, 607/9, 607/14, 607/17, 607 25- 26, 600/509, 600/516, 600/517
• US Class Current: 607/4
• CPC Class Codes: A61N 1/3684 for stimulating the heart at multiple sites of the ventricle or the atrium
• CPC Class Codes: A61N 1/36842 Multi-site stimulation in the same chamber
• CPC Class Codes: A61N 1/36843 Bi-ventricular stimulation
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/39622 Pacing therapy

Abstract

A method and apparatus for cardioverting the atrium of a human heart that includes insertion of first and second elongated electrodes tranvenously into the heart and associated vessels. One electrode is preferably located in the coronary sinus and great vein of the heart. The other electrode is preferably located in the vicinity of the right atrium of the heart, spaced from the electrode located in the coronary sinus. In response to detection of fibrillation or in response to manual triggering, a defibrillation pulse is applied between the first and second electrodes to effect atrial cardioversion. Further, after delivery of a successful defibrillation shock, the width of intrinsic p-waves are monitored and bi-atrial pacing is temporarily initiated if the width exceeds a preset or programmable threshold.

Claims

1. A method for implementing atrial defibrillation, comprising the steps of:

delivering a first therapy in response to detection of an atrial tachyarrhythmia of a patient;

determining whether the first therapy was successful;

determining, following a determination that the first therapy was successful, variations in morphology of a subsequent waveform representation of a cardiac cycle of the patient; and

delivering a second therapy in response to both determining the first therapy was successful and the determined variations.

2. The method of claim 1, wherein the step of determining variations determines whether a width of a p-wave is greater than a predetermined threshold width.

3. The method of claim 2 wherein the predetermined threshold width is greater than a normal intrinsic width of a p-wave.

4. The method of claim 3, wherein the predetermined threshold width is between approximately 10 and 50 msec greater than the normal intrinsic width of a p-wave.

5. The method of claim 2, wherein the predetermined threshold width is of a proportionately greater measure over a normal width of a p-wave.

6. The method of claim 5, wherein the proportionately greater measure includes a percent increase between approximately 5 and 20 percent.

7. The method of claim 1, wherein the second therapy is delivered for a predetermined time period.

8. The method of claim 7, wherein the predetermined time period is between approximately 1 and 5 minutes.

9. The method of claim 1, wherein the step of determining variations further comprises determining, after delivery of the second therapy, whether a width of a subsequent p-wave is greater than a predetermined threshold width.

10. The method of claim 9, wherein delivery of the second therapy is repeated in response to the width of the subsequent p-wave being greater than the predetermined threshold width.

11. The method of claim 1, further comprising the step of amplifying a signal between electrodes for generating the subsequent waveform representation.

12. The method of claim 11, wherein the electrodes comprise subcutaneous electrode array electrodes.

13. An implantable medical device, comprising:

means for delivering a first therapy in response to detection of an atrial tachyarrhythmia;

means for determining whether the first therapy was successful;

an amplifier sensing p-waves between electrodes and providing an output signal representative of the morphology of a sensed p-wave;

a pacer timing/control circuit receiving the amplifier output signal and, following a determination that the first therapy was successful, delivering a second therapy in response to both determining the first therapy was successful and detection of variations in morphology of subsequent sensed p-waves.

14. The device of claim 13, wherein the pacer timing/control circuit determines whether a width of a p-wave is greater than a predetermined threshold width.

15. The device of claim 14 wherein the predetermined threshold width is greater than a normal intrinsic width of a p-wave.

16. The device of claim 15, wherein the predetermined threshold width is between approximately 10 and 50 msec greater than the normal intrinsic width of a p-wave.

17. The device of claim 14, wherein the predetermined threshold width is a proportionately greater measure over a normal width of a p-wave.

18. The device of claim 17, wherein the proportionately greater measure includes a percent increase between approximately 5 and 20 percent.

19. The device of claim 13, wherein the pacer timing/control circuit determines, subsequent to delivery of the second therapy, whether a width of a subsequent p-wave is greater than a predetermined threshold width.

20. The device of claim 19, wherein delivery of the second therapy is repeated in response to the width of the subsequent p-wave being greater than the predetermined threshold width.

21. The device of claim 13, wherein the first therapy is a defibrillation pulse and the second therapy is bi-atrial pacing.

22. The device of claim 13, wherein the electrodes comprise subcutaneous electrode array electrodes.

23. An implantable medical device, comprising:

means for delivering a first therapy in response to detection of an atrial tachyarrhythmia of a patient;

means for determining whether the first therapy was successful;

means for determining, following a determination that the first therapy was successful, variations in morphology of a subsequent waveform representation of a cardiac cycle of the patient; and

means for delivering a second therapy in response to both the atrial tachyarrhythmia not being detected subsequent to the delivered first therapy and the determined variations.

24. The device of claim 23, wherein the means for determining variations determines whether a width of a p-wave is greater than a predetermined threshold width.

25. The device of claim 24 wherein the predetermined threshold width is greater than a normal intrinsic width of a p-wave.

26. The device of claim 25, wherein the predetermined threshold width is between approximately 10 and 50 msec greater than the normal intrinsic width of a p-wave.

27. The device of claim 24, wherein the predetermined threshold width is of a proportionately greater measure over a normal width of a p-wave.

28. The device of claim 27, wherein the proportionately greater measure includes a percent increase between approximately 5 and 20 percent.

29. The device of claim 23, wherein the means for delivering a second therapy delivers the second therapy for a predetermined time period.

30. The device of claim 29, wherein the predetermined time period is between approximately 1 and 5 minutes.

31. The device of claim 23, wherein the means for determining variations determines, after delivery of the second therapy, whether a width of a subsequent p-wave is greater than a predetermined threshold width.

32. The device of claim 31, wherein the means for delivering a second therapy repeats delivery of the second therapy in response to the width of the subsequent p-wave being greater than the predetermined threshold width.

33. The device of claim 23, further comprising means for amplifying a signal between electrodes for generating the subsequent waveform representation.

34. The device of claim 33, wherein the electrodes comprise subcutaneous electrode array electrodes.

35. The device of claim 23, wherein the first therapy is a defibrillation pulse and the second therapy is bi-atrial pacing.