Real time self-adjusting calibration algorithm
First Claim
1. A method of calibrating glucose monitor data, the method comprising the steps of:
- sampling glucose monitor data from a sensor at a predetermined sampling rate;
deriving interval values from the sampled glucose monitor data over a predetermined interval rate;
applying clipping limits to the derived interval values;
deriving at least one glucose monitor data point by averaging the derived interval values at a predetermined memory storage rate;
obtaining from another blood glucose measuring device at least one blood glucose reference reading that is temporally associated with at least one glucose monitor data point;
calibrating the sampled glucose monitor data using the at least one blood glucose reference reading and the corresponding at least one glucose monitor data point.
0 Assignments
0 Petitions
Accused Products
Abstract
A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression. Alternatively, the calculation of the calibration characteristics is obtained using non-linear regression.
-
Citations
46 Claims
-
1. A method of calibrating glucose monitor data, the method comprising the steps of:
-
sampling glucose monitor data from a sensor at a predetermined sampling rate; deriving interval values from the sampled glucose monitor data over a predetermined interval rate; applying clipping limits to the derived interval values; deriving at least one glucose monitor data point by averaging the derived interval values at a predetermined memory storage rate; obtaining from another blood glucose measuring device at least one blood glucose reference reading that is temporally associated with at least one glucose monitor data point; calibrating the sampled glucose monitor data using the at least one blood glucose reference reading and the corresponding at least one glucose monitor data point. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
-
-
24. An article of manufacture containing code for calibrating glucose monitor data, comprising a computer usable medium including at least one embedded computer program that is capable of causing at least one computer to perform:
-
sampling glucose monitor data from a sensor at a predetermined sampling rate; deriving interval values from the sampled glucose monitor data over a predetermined interval rate; applying clipping limits to the derived interval values; deriving at least one glucose monitor data point by averaging the derived interval values at a predetermined memory storage rate; obtaining from another blood glucose measuring device at least one blood glucose reference reading that is temporally associated with at least one glucose monitor data point; calibrating the sampled glucose monitor data using the at least one blood glucose reference reading and the corresponding at least one glucose monitor data point. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46)
-
Specification