Combating Parkinson's disease-related movement disorder

• US 7,030,108 B2
• Filed: 08/27/2001
• Issued: 04/18/2006
• Est. Priority Date: 09/15/1999
• Status: Expired due to Fees

• Current Assignee: Reed Richter, Steven J. Hultquist
• Original Assignee: Reed Richter, Steven J. Hultquist
• Inventors: Giduz, Thomas, Richter, Virginia Pact
• Primary Examiner(s): Spivack, Phyllis G.
• Application Number:
  US09/940,309
• Publication Number:
  US 20020035057A1
• Time in Patent Office: 1,695 Days
• Field of Search: 514/214.02
• US Class Current: 514/214.02
• CPC Class Codes: A61K 31/00 Medicinal preparations containing organic active ingredients
• CPC Class Codes: A61K 31/55 having seven-membered rings, e.g. azelastine, pentylenetetrazole
• CPC Class Codes: A61P 25/14 for treating abnormal movements, e.g. chorea, dyskinesia
• CPC Class Codes: A61P 25/16 Anti-Parkinson drugs

Abstract

A method of combating movement disorder is disclosed in a patient with Parkinson'"'"'s disease comprising administering an effective amount of mirtazapine, a receptor antagonist for 5HT_2/3 and α₂ receptors.

Claims

1. A method of combating Parkinson'"'"'s disease-related movement disorder in a patient experiencing or susceptible to same who is being treated with dopaminergic medication, anticonvulsant medication or antianxiolytic medication, said method comprising administering to the patient an effective amount of mirtazapine.

2. The method of claim 1, wherein said patient is being treated with dopaminergic medication.

3. The method of claim 2, wherein said dopaminergic medication comprises a dopa agonist.

4. The method of claim 2, wherein said dopaminergic medication comprises medication selected from the group consisting of (i) levodopa, (ii) levodopa in combination with carbidopa, and (iii) ropirinole.

5. The method of claim 1, wherein said patient is being treated with anticonvulsant medication.

6. The method of claim 5, wherein said anticonvulsant medication comprises primidone.

7. The method of claim 1, wherein said movement disorder comprises bradykinesia.

8. The method of claim 1, wherein said movement disorder comprises resting tremor.

9. The method of claim 1, wherein said movement disorder comprises tremor.

10. The method of claim 1, wherein said movement disorder comprises action tremor.

11. The method of claim 1, wherein said patient is being treated with anxiolytic medication.

12. The method of claim 11, wherein said anxiolytic medication comprises propranolol.

13. The method of claim 11, wherein said anxiolytic medication comprises an SSRI.

14. The method of claim 11, wherein said anxiolytic medication comprises a benzodiazapine.