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Controlled dosage drug delivery

  • US 7,031,768 B2
  • Filed: 06/10/2002
  • Issued: 04/18/2006
  • Est. Priority Date: 08/31/1998
  • Status: Expired due to Term
First Claim
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1. A method of providing reliable dosage ratings for the administration of therapeutic agents in transdermal iontophoresis devices that include a reservoir for holding a therapeudic agent comprising steps of:

  • (a) providing a commonly manufactured lot of galvanic battery power sources each power source including(i) an oxidizable species and a reducible species wherein said self-contained galvanic power source provides the sole source of both the power and control for dosage delivery and contains a lesser amount of a selected one of said oxidizable species and reducible species;

    (ii) a common conductor for carrying said oxidizable species and said reducible species;

    (b) determining by sample testing in accordance with lot size characteristics of said lot including an average charge capacity for said galvanic battery power sources of said lot to produce a tested lot;

    (c) incorporating a galvanic power source from said tested lot into each said device;

    (d) labeling a delivery dosage rating for said devices as verified by said average charge capacity of said tested lot.

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