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Medicament vial having a heat-sealable cap, and apparatus and method for filling the vial

  • US 7,032,631 B2
  • Filed: 01/28/2004
  • Issued: 04/25/2006
  • Est. Priority Date: 02/11/2000
  • Status: Expired due to Term
First Claim
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1. A thermoplastic stopper defining a needle penetration region that is pierceable with a needle to form a needle aperture therethrough, and is heat resealable to hermetically seal the needle aperture by applying laser radiation at a predetermined wavelength and power thereto, wherein the stopper comprises a thermoplastic body defining a predetermined wall thickness in an axial direction thereof, and including (i) a styrene block copolymer;

  • (ii) an olefin;

    (iii) a predetermined amount of pigment that allows the body to substantially absorb laser radiation at the predetermined wavelength and substantially prevent the passage of radiation through the predetermined wall thickness thereof, and hermetically seal a needle aperture formed in the needle penetration region thereof in a predetermined time period of less than approximately 2 seconds; and

    (iv) a predetermined amount of lubricant that reduces friction forces at an interface of the needle and body during needle penetration thereof.

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