Polycationic peptide coatings and methods of coating implantable medical devices
First Claim
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1. A therapeutic composition, comprising a polycationic peptide and a hydrophobic counter-ion coordinated with the polycationic peptide.
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Abstract
Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
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29 Claims
- 1. A therapeutic composition, comprising a polycationic peptide and a hydrophobic counter-ion coordinated with the polycationic peptide.
- 10. A method for making a polycationic peptide soluble in an organic solvent, comprising preparing a complex of the peptide with a hydrophobic counter-ion.
- 20. A coating for an implantable medical device, the coating comprising a polycationic peptide and a hydrophobic counter-ion coordinated with the polycationic peptide.
Specification