Integrated automatic blood processing unit
First Claim
Patent Images
1. A system for separating blood components from a buffy coat, comprising:
- at least one buffy coat bag to contain at least one unit of buffy coat, each of said at least one buffy coat bag in fluid communication with an input tubing by a sterile dock;
one buffy coat valve for each of said at least one buffy coat bag, each of said buffy coat valves configured on said input tubing segment so as to individually control the flow of buffy coat from one of said at least one buffy coat bag;
a continuous flow centrifuge (“
CFC”
) to separate platelet products from white cell products in said buffy coat, said CFC in fluid communication with said at least one buffy coat bag said input tubing, said input tubing terminating at said CFC;
a platelet additive solution (“
PAS”
) bag to contain PAS, said PAS bag in fluid communication with said input tubing by a PAS tubing segment, said PAS tubing segment terminating at a first end at said PAS bag, and terminating at its second end at a PAS junction located between all of said at least one buffy coat valve and said CFC;
a PAS pump to pump said PAS from said PAS bag, said PAS pump configured on said PAS tubing segment;
a bacterial filter to maintain sterility of said system, said bacterial filter configured on said PAS tubing segment between said PAS pump and said PAS bag;
a cell pump to pump said PAS and said buffy coat to said CFC, said cell pump configured on said input tubing between said PAS junction and said CFC;
a platelet product bag to contain platelet product separated from buffy coat by said CFC, said platelet product bag in fluid communication with said CFC by a platelet tubing segment;
a platelet pump to pump said platelet product from said CFC to said platelet product bag, said platelet pump configured on said platelet tubing segment;
a white cell product bag to contain white cell product separated from buffy coat by said CFC, said white cell product bag in fluid communication with said CFC by a white cell tubing segment;
a platelet valve to control the flow of said platelet product from said CFC, said platelet valve configured on said platelet tubing segment between said CFC and said platelet pump;
a white cell valve to control the flow of said white cell product from said CFC, said white cell valve configured on said white cell tubing segment between said CFC and said white cell product bag;
a supplemental valve to control a flow of fluid between said platelet tubing segment and said white cell tubing segment, said supplemental valve configured on a supplemental tubing segment, said supplemental tubing segment in fluid communication with said platelet tubing segment at a platelet junction on said platelet tubing segment between said platelet valve and said platelet pump, and said supplemental tubing segment in fluid communication with said white cell tubing segment at a white cell junction on said white cell tubing segment between said CFC and said white cell valve; and
a cassette through which said input tubing, PAS tubing segment, platelet tubing segment, white cell tubing segment and supplemental tubing segment pass.
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Accused Products
Abstract
A system for automatically processing blood components is described. The system includes a console, which contains all motors, pumps, sensors, valves and control circuitry, and a unique disposable set that includes a cassette supporting a centrifuge with an improved design, pump interfaces with an improved design, component and solution bags, and tubing. Various processes are implemented using a specific disposable set for each process which allows automatic identification of the process to be performed the console.
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Citations
6 Claims
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1. A system for separating blood components from a buffy coat, comprising:
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at least one buffy coat bag to contain at least one unit of buffy coat, each of said at least one buffy coat bag in fluid communication with an input tubing by a sterile dock; one buffy coat valve for each of said at least one buffy coat bag, each of said buffy coat valves configured on said input tubing segment so as to individually control the flow of buffy coat from one of said at least one buffy coat bag; a continuous flow centrifuge (“
CFC”
) to separate platelet products from white cell products in said buffy coat, said CFC in fluid communication with said at least one buffy coat bag said input tubing, said input tubing terminating at said CFC;a platelet additive solution (“
PAS”
) bag to contain PAS, said PAS bag in fluid communication with said input tubing by a PAS tubing segment, said PAS tubing segment terminating at a first end at said PAS bag, and terminating at its second end at a PAS junction located between all of said at least one buffy coat valve and said CFC;a PAS pump to pump said PAS from said PAS bag, said PAS pump configured on said PAS tubing segment; a bacterial filter to maintain sterility of said system, said bacterial filter configured on said PAS tubing segment between said PAS pump and said PAS bag; a cell pump to pump said PAS and said buffy coat to said CFC, said cell pump configured on said input tubing between said PAS junction and said CFC; a platelet product bag to contain platelet product separated from buffy coat by said CFC, said platelet product bag in fluid communication with said CFC by a platelet tubing segment; a platelet pump to pump said platelet product from said CFC to said platelet product bag, said platelet pump configured on said platelet tubing segment; a white cell product bag to contain white cell product separated from buffy coat by said CFC, said white cell product bag in fluid communication with said CFC by a white cell tubing segment; a platelet valve to control the flow of said platelet product from said CFC, said platelet valve configured on said platelet tubing segment between said CFC and said platelet pump; a white cell valve to control the flow of said white cell product from said CFC, said white cell valve configured on said white cell tubing segment between said CFC and said white cell product bag; a supplemental valve to control a flow of fluid between said platelet tubing segment and said white cell tubing segment, said supplemental valve configured on a supplemental tubing segment, said supplemental tubing segment in fluid communication with said platelet tubing segment at a platelet junction on said platelet tubing segment between said platelet valve and said platelet pump, and said supplemental tubing segment in fluid communication with said white cell tubing segment at a white cell junction on said white cell tubing segment between said CFC and said white cell valve; and a cassette through which said input tubing, PAS tubing segment, platelet tubing segment, white cell tubing segment and supplemental tubing segment pass. - View Dependent Claims (2, 3, 4, 5)
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6. A method of separating blood components from a buffy coat, comprising:
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providing a system for separating blood components from a buffy coat, including at least one buffy coat bag containing at least one buffy coat, each of said at least one buffy coat bag in fluid communication with an input tubing, a platelet additive solution (“
PAS”
) bag containing PAS, said PAS bag in fluid communication with said input tubing by a PAS tubing segment, said tubing segment terminating at a first end at said PAS bag, and terminating at its second end at a PAS junction,a continuous flow centrifuge (“
CFC”
) adapted to separate a platelet product and a white cell product from a buffy coat, said CFC in fluid communication with said at least one buffy coat bag, said PAS bag, a platelet product bag and a white cell product bag by way of tubing, wherein said PAS junction is located between all of said at least one buffy coat bag and said CFC,a cassette through which said tubing passes, and a cell pump to pump said PAS and said buffy coat to said CFC, said cell pump configured on said input tubing between said PAS junction and said CFC; configuring said system system with a console including electronic and mechanical components to operate said system; and operating said system to separate blood components from a buffy coat.
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Specification