Method and apparatus for detecting oscillations in cardiac rhythm

• US 7,039,462 B2
• Filed: 06/14/2002
• Issued: 05/02/2006
• Est. Priority Date: 06/14/2002
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Pastore, Joseph M., Zhu, Qingsheng, Ding, Jiang, Salo, Rodney W., Ni, Quan
• Primary Examiner(s): Bockelman, Mark
• Application Number:
  US10/172,825
• Publication Number:
  US 20030233132A1
• Time in Patent Office: 1,418 Days
• Field of Search: 600/508, 600/547, 607/17, 607/24, 607/28, 607/14
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/365 controlled by a physiological parameter, e.g. heart potential evoked response A61N1/371
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting

Abstract

A cardiac rhythm management device is configured to detect mechanical oscillations in cardiac rhythm. Upon detection of such oscillations, the device may adjust its operating behavior to compensate for the deleterious effects of the condition.

Claims

1. An implantable cardiac rhythm management device, comprising:

an exciter for generating an excitation current between excitation electrodes;

voltage sense electrodes for generating an impedance signal corresponding to cardiac volume when the excitation current is applied; and

circuitry for processing the impedance signal to detect oscillations in cardiac volume during successive heart beats and to detect volumetric alternans when the measured oscillations exceed a specified magnitude for a specified number of beats.

2. The device of claim 1 further comprising a device controller and wherein the controller is programmed to adjust the operating behavior of the device when volumetric alternans is detected.

3. The device of claim 2 further comprising:

a first atrial pacing channel;

a second atrial pacing channel; and

,

wherein the controller is programmed to deliver pacing therapy in accordance with a bradycardia mode, and further wherein the controller is programmed to initiate atrial resynchronization pacing by delivering paces through both atrial channels when volumetric alternans is detected.

4. The device of claim 2 further comprising:

a sensing/pacing channel; and

wherein the controller is programmed to deliver pacing therapy in accordance with a bradycardia mode, and further wherein the controller is programmed to decrease a programmed pacing rate when volumetric alternans is detected.

5. The device of claim 2 further comprising:

a sensing/pacing channel; and

wherein the controller is programmed to deliver anti-tachycardia pacing therapy when a measured heart rate exceeds a specified tachycardia threshold rate, and further wherein the controller is programmed to decrease the tachycardia threshold rate when volumetric alternans is detected.

6. The device of claim 2 further comprising:

a first ventricular pacing channel;

a second ventricular pacing channel; and

wherein the controller is programmed to deliver pacing therapy in accordance with a bradycardia mode, and further wherein the controller is programmed to initiate ventricular resynchronization pacing by delivering paces through both ventricular pacing channels when volumetric alternans is detected.

7. The device of claim 2 further comprising:

a first ventricular pacing channel;

a second ventricular pacing channel; and

wherein the controller is programmed to deliver ventricular resynchronization pacing by delivering paces through both ventricular channels, and further programmed to adjust a resynchronization operating parameter when volumetric alternans is detected.

8. The device of claim 7 wherein the resynchronization operating parameter adjusted by the controller is an atrio-ventricular interval.

9. The device of claim 7 wherein the resynchronization operating parameter adjusted by the controller is a biventricular delay interval.

10. The device of claim 2 further comprising:

a ventricular pacing channel; and

wherein the controller is programmed to initiate ventricular resynchronization pacing by delivering left-ventricular only pacing when volumetric alternans is detected.

11. The device of claim 2 further comprising:

a plurality of ventricular pacing channels; and

wherein the controller is programmed to initiate ventricular resynchronization pacing by delivering multi-site pacing to the left ventricle when volumetric alternans is detected.

12. A method for operating an implantable cardiac rhythm management device, comprising:

generating an excitation current between excitation electrodes;

generating an impedance signal corresponding to cardiac volume when the excitation current is applied; and

processing the impedance signal to detect oscillations in cardiac volume during successive heart beats and to detect volumetric alternans when the measured oscillations exceed a specified magnitude for a specified number of beats.

13. The method of claim 12 further comprising adjusting the operating behavior of the device when volumetric alternans is detected.

14. The method of claim 12 further comprising initiating atrial resynchronization pacing by delivering paces through both atrial channels when volumetric alternans is detected.

15. The method of claim 12 further comprising delivering pacing therapy in accordance with a bradycardia mode and decreasing a programmed pacing rate when volumetric alternans is detected.

16. The method of claim 12 further comprising delivering anti-tachycardia pacing therapy when a measured heart rate exceeds a specified tachycardia threshold rate and decreasing the tachycardia threshold rate when volumetric alternans is detected.

17. The method of claim 12 further comprising initiating ventricular resynchronization pacing by delivering paces to both ventricles when volumetric alternans is detected.

18. The method of claim 12 further comprising delivering ventricular resynchronization pacing by delivering paces through both ventricular channels and adjusting a resynchronization operating parameter when volumetric alternans is detected.

19. The method of claim 18 wherein the adjusted resynchronization operating parameter is an atrio-ventricular interval.

20. The method of claim 18 wherein the adjusted resynchronization operating parameter is a biventricular delay interval.

21. The method of claim 12 further comprising initiating atrial resynchronization pacing by delivering paces through both atrial channels when volumetric alternans is detected.

22. The method of claim 12 further comprising initiating ventricular resynchronization pacing by delivering left-ventricular only pacing when volumetric alternans is detected.

23. The method of claim 12 further comprising initiating ventricular resynchronization pacing by delivering multi-site pacing to the left ventricle when volumetric alternans is detected.