Medicament inhalation delivery devices and methods for using the same
First Claim
1. A medicament delivery device for administering an inhalable medicament to a user, said device comprising:
- a) a medicament reservoir;
b) an entrance port and an exit port each disposed adjacent said reservoir;
c) a gas chamber disposed adjacent said entrance port;
d) a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure;
e) a first frangible membrane extending across said entrance port and separating said reservoir from said gas chamber; and
f) a second frangible membrane extending across said exit port;
g) a tube disposed adjacent said exit port and defining a delivery opening opposite said exit port, said delivery opening being open prior to actuation of said pressurizing mechanism;
h) a piercing member configured to initially engage said first membrane on a surface of said first membrane facing said reservoir;
i) wherein, when said pressurizing mechanism is actuated, said piercing member engages and disrupts said first membrane to allow gas to flow through said first membrane and said entrance port and said reservoir and to carry the medicament through said exit port.
1 Assignment
0 Petitions
Accused Products
Abstract
A medicament delivery device for administering a medicament to a user includes a medicament reservoir and an entrance port and an exit port each disposed adjacent the reservoir. A gas chamber disposed adjacent the entrance port. The device includes a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure. A first frangible membrane extends across the entrance port and separates the reservoir from the gas chamber. A second frangible membrane extends across the exit port. When the pressurizing mechanism is attached, at least one of the first and second membranes is responsive to the prescribed pressure in the gas chamber to burst to allow gas to flow through the entrance port and the reservoir and to carry the medicament through the exit port.
-
Citations
44 Claims
-
1. A medicament delivery device for administering an inhalable medicament to a user, said device comprising:
-
a) a medicament reservoir; b) an entrance port and an exit port each disposed adjacent said reservoir; c) a gas chamber disposed adjacent said entrance port; d) a pressurizing mechanism operable to pressurize said gas chamber to at least a prescribed pressure; e) a first frangible membrane extending across said entrance port and separating said reservoir from said gas chamber; and f) a second frangible membrane extending across said exit port; g) a tube disposed adjacent said exit port and defining a delivery opening opposite said exit port, said delivery opening being open prior to actuation of said pressurizing mechanism; h) a piercing member configured to initially engage said first membrane on a surface of said first membrane facing said reservoir; i) wherein, when said pressurizing mechanism is actuated, said piercing member engages and disrupts said first membrane to allow gas to flow through said first membrane and said entrance port and said reservoir and to carry the medicament through said exit port. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
-
-
25. A method for administering an inhalable medicament to a user, said method comprising the steps of:
-
a) providing a medicament delivery device including; 1) a medicament reservoir; 2) an entrance port and an exit port each disposed adjacent the reservoir; 3) a gas chamber disposed adjacent the entrance port; 4) a pressurizing mechanism including a compressible blister defining said gas chamber operable to pressurize the gas chamber to at least a prescribed pressure; 5) a piercing member configured to initially engage said first membrane on a surface of said first membrane facing said reservoir; 6) a first frangible membrane extending across the entrance port and separating the reservoir from the gas chamber; and 7) a second frangible membrane extending across the exit port; and b) actuating the pressurizing mechanism to generate the prescribed pressure in the gas chamber, whereupon at the first membrane is penetrated by said piercing member to allow gas to flow past at least the first membrane and through the entrance port and the reservoir and to carry the medicament through the exit port. - View Dependent Claims (26, 27, 28)
-
-
29. A method for administering an inhalable medicament to a user, said method comprising the steps of:
-
a) providing a medicament delivery device including; 1) a medicament reservoir; 2) an entrance port and an exit port each disposed adjacent the reservoir; 3) a compressible blister defining a gas chamber and operable to pressurize the gas chamber to at least a prescribed pressure; and 4) a frangible membrane extending across the entrance port and separating the reservoir from the gas chamber; 5) a piercing member configured to initially engage said first membrane on a surface of said first membrane facing said reservoir; and b) compressing the blister to generate the prescribed pressure in the gas chamber, whereupon said piercing member engages and disrupts said frangible membrane to allow gas to flow past said membrane and through the entrance port and the reservoir and to carry the medicament through the exit port. - View Dependent Claims (30, 31, 32)
-
-
33. A medicament delivery device for administering an inhalable medicament to a user, comprising:
-
a medicament reservoir, an inlet port communicating with said medicament reservoir, an outlet port communicating with said medicament reservoir, and a thin polymeric frangible membrane located between said outlet port and said medicament reservoir sealing said outlet port, said delivery opening being open prior to said thin polymeric frangible membrane being broken, a piercing member located between said inlet port and said outlet port and said piercing member is configured to initially engage said thin polymeric burstable membrane on a surface of said thin polymeric burstable membrane facing said reservoir, whereby fluid pressure delivered to said reservoir will activate said piercing member to disrupt said thin polymeric burstable membrane, fluidize medicament contained in said medicament reservoir and deliver fluidized medicament to said outlet port. - View Dependent Claims (34, 35, 36, 37, 38, 39, 40)
-
-
41. A medicament delivery device for administering an inhalable medicament to a user, said device comprising:
-
a) a medicament reservoir; b) an entrance port and an exit port each disposed adjacent said reservoir; c) a gas chamber disposed adjacent said entrance port; d) a pressurizing mechanism including a compressible blister defining said gas chamber and operable to pressurize said gas chamber to at least a prescribed pressure; e) a first frangible membrane extending across said entrance port and separating said reservoir from said gas chamber; and f) a second frangible membrane extending across said exit port; g) a tube disposed adjacent said exit port and defining a delivery opening opposite said exit port, said delivery opening being open prior to actuation of said pressurizing mechanism; h) a piercing member responsive to said pressurizing mechanism; i) wherein, when said pressurizing mechanism is actuated, said blister is compressed and the size of said entrance port is increased to distort said first membrane and said piercing member engages and disrupts said first membrane in said gas chamber to allow gas to flow through said first membrane and said entrance port and said reservoir and to carry the medicament through said exit port. - View Dependent Claims (42, 43, 44)
-
Specification