Method for controlling a ventilator, and system therefor

• US 7,040,321 B2
• Filed: 03/28/2002
• Issued: 05/09/2006
• Est. Priority Date: 03/30/2001
• Status: Active Grant

• Current Assignee: Avent Incorporated (Avanos Medical, Inc.)
• Original Assignee: Microcuff GmbH (Avanos Medical, Inc.)
• Inventors: Göbel, Fred
• Primary Examiner(s): Dawson, Glenn K.
• Application Number:
  US10/109,554
• Publication Number:
  US 20030000526A1
• Time in Patent Office: 1,503 Days
• Field of Search: 604 9601-10314, 128/200.24, 128/203.12, 128/203.14, 128/203.24, 12820418-20423, 128/204.29, 128/205.23, 12820714-20718, 128/203.15, 128/203.21, 128/200.14, 128/202.15, 128/204.26, 128/205.11, 128/205.24, 606191-200, 600/201, 600/204, 600/207
• US Class Current: 128/207.15
• CPC Class Codes: A61B 5/037 Measuring oesophageal pressure
• CPC Class Codes: A61B 5/087 Measuring breath flow
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/0409 with mean for closing the oesophagus
• CPC Class Codes: A61M 16/0415 with access means to the stomach
• CPC Class Codes: A61M 16/044 External cuff pressure control or supply, e.g. synchronisation with respiration
• CPC Class Codes: A61M 16/0452 following the inspiration and expiration pressure
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2205/3344 Measuring or controlling pressure at the body treatment site
• CPC Class Codes: A61M 2210/105 Oesophagus

Abstract

A method for controlling breathing gas flow of a ventilator for assisted or controlled ventilation of a patient as a function of a tracheobronchial airway pressure of the patient. A ventilator tube, such as a tracheal tube or tracheostomy tube, can be introduced into a trachea of the patient and subjected to the breathing gas, and has an inflatable cuff and at least one lumen that is continuous from a distal end of the tube to a proximal end of the tube. An apparatus detects an airway pressure, in which the tracheobronchial airway pressure is ascertained by continuous or intermittent detection and evaluation of an intra-cuff pressure prevailing in the cuff of the tube inserted into the trachea. The breathing gas flow of the ventilator is controlled as a function of the intra-cuff pressure detected.

Claims

1. In a method for controlling a flow of breathing gas in a ventilator for assisted or controlled ventilation of a patient as a function of a tracheobronchial airway pressure of the patient, having one of a ventilator tube, a tracheal tube and a tracheostomy tube, which can be introduced into a trachea of the patient and can be subjected to the breathing gas and which has an inflatable cuff and at least one lumen that is continuous from a distal end of the ventilator tube to a proximal end of the ventilator tube, and wherein an airway pressure is detected, the improvement comprising:

determining the tracheobronchial airway pressure by one of continuous and intermittent detection and evaluation of an intra-cuff pressure prevailing in the cuff of the tube inserted into the trachea, and controlling the flow of the breathing gas in the ventilator as a function of a detected intra-cuff pressure, determining a pressure difference (Δ

P) generated by the ventilator to overcome a flow resistance of the tube as a function of the pressure difference between the pressure at the proximal end of the tube and the tracheobronchial airway pressure at the distal end of the tube by measurement of the pressure at the proximal end of the tube and the intra-cuff pressure, and using a Δ

P to calculate a compensatory constant, and adapting dynamically the compensatory constant from one breathing stroke to another breathing stroke during respiration by the ventilator, to a respective current flow resistance of the tube.

2. In the method of claim 1 wherein the cuff is subjected to a fill pressure ≦

25 mbar.

3. In the method of claim 2, wherein the cuff is subjected to a fill pressure ≦

15 mbar.

4. In the method of claim 3, wherein the tube with the cuff of a stretchable thin plastic film with a wall thickness of less than 0.02 mm is used.

5. In the method of claim 4, wherein the cuff is made from a film of thermoplastic polyurethane elastomer with a modulus of tension of at least 10 MPa at 300% expansion in accordance with ASTM D 412, and is used for the tube.

6. In the method of claim 5, wherein a differential value that trips a breathing stroke of the ventilator is specified in a cuff fill pressure as a trigger threshold for the ventilator, and if an intra-cuff pressure drops during an onset of thoracic inspiration by the patient to below the trigger threshold the ventilator is activated and trips a machine-supported breathing stroke.

7. In the method of claim 6, wherein during controlled respiration, values obtained by measuring the intra-cuff pressure are used to control an upper pressure function of the upper pressure limit (Pmax) of the ventilator so that the ventilator on attaining a predetermined upper pressure one of switches off a delivery of the breathing gas and switches over to exhalation.

8. In the method of claim 7, wherein for optimizing control of the ventilator, a gastric probe having an inflatable balloon that can be subjected to a fill pressure of ≦

25 mbar is introduced into an esophagus of the patient, and an esophageal balloon pressure prevailing in the balloon of the gastric probe is detected one of continuously and intermittently, and pressure fluctuations in an intrathoracic pressure transmitted to the gastric probe balloon are detected and evaluated and supplied to the ventilator for controlling the flow of breathing gas.

9. In the method of claim 8, wherein the intra-cuff pressure of the tube is measured by a measuring instrument, and measured values are transmitted by a measuring line that extends from the cuff of the tube to one of the ventilator and a control device for the ventilator.

10. In the method of claim 9, wherein the esophageal balloon pressure in the balloon of the gastric probe introduced into the esophagus is measured and second measured values are transmitted from the balloon to one of the ventilator and a control device for the ventilator.

11. In the method of claim 10, wherein values obtained by measuring the esophageal balloon pressure are used to ascertain a respiratory work done by the patient, and from breathing strokes pressure-supported by the ventilator of respiratory cycles of fixed duration cyclical breathing work diagrams are determined and displayed on a monitor as one of loops and areas.

12. In the method of claim 1, wherein the cuff is subjected to a fill pressure ≦

15 mbar.

13. In the method of claim 1, wherein the tube with the cuff of a stretchable thin plastic film with a wall thickness of less than 0.02 mm is used.

14. In the method of claim 1, wherein the cuff is made from a film of thermoplastic polyurethane elastomer with a modulus of tension of at least 10 MPa at 300% expansion in accordance with ASTM D 412, and is used for the tube.

15. In the method of claim 1, wherein a differential value that trips a breathing stroke of the ventilator is specified in a cuff fill pressure as a trigger threshold for the ventilator, and if an intra-cuff pressure drops during an onset of thoracic inspiration by the patient to below the trigger threshold the ventilator is activated and trips a machine-supported breathing stroke.

16. In the method of claim 1, wherein for optimizing control of the ventilator, a gastric probe having an inflatable balloon that can be subjected to a fill pressure of ≦

25 mbar is introduced into an esophagus of the patient, and an esophageal balloon pressure prevailing in the balloon of the gastric probe is detected one of continuously and intermittently, and pressure fluctuations in an intrathoracic pressure transmitted to the gastric probe balloon are detected and evaluated and supplied to the ventilator for controlling the flow of breathing gas.

17. In the method of claim 1, wherein the intra-cuff pressure of the tube is measured by a measuring instrument, and measured values are transmitted by a measuring line that extends from the cuff of the tube to one of the ventilator and a control device for the ventilator.

18. In a method for controlling a flow of breathing gas in a ventilator for assisted or controlled ventilation of a patient as a function of a tracheobronchial airway pressure of the patient, having one of a ventilator tube, a tracheal tube and a tracheostomy tube, which can be introduced into a trachea of the patient and can be subjected to the breathing gas and which has an inflatable cuff and at least one lumen that is continuous from a distal end of the ventilator tube to a proximal end of the ventilator tube, and wherein an airway pressure is detected, the improvement comprising:

determining the tracheobronchial airway pressure by one of continuous and intermittent detection and evaluation of an intra-cuff pressure prevailing in the cuff of the tube inserted into the trachea, and controlling the flow of the breathing gas in the ventilator as a function of a detected intra-cuff pressure, and during controlled respiration, using values obtained by measuring the intra-cuff pressure to control an upper pressure function of the upper pressure limit (Pmax) of the ventilator so that the ventilator on attaining a predetermined upper pressure one of switches off a delivery of the breathing gas and switches over to exhalation.

19. In the method of claim 18, wherein a pressure difference (Δ

P) generated by the ventilator to overcome a flow resistance of the tube is determined as a function of the pressure difference between the pressure at the proximal end of the tube and the tracheobronchial airway pressure at the distal end of the tube by measurement of the pressure at the proximal end of the tube and the intra-cuff pressure, and a Δ

P is used to calculate a compensatory constant, and the compensatory constant is adapted dynamically from one breathing stroke to another breathing stroke during respiration by the ventilator, to a respective current flow resistance of the tube.

20. In a method for controlling a flow of breathing gas in a ventilator for assisted or controlled ventilation of a patient as a function of a tracheobronchial airway pressure of the patient, having one of a ventilator tube, a tracheal tube and a tracheostomy tube, which can be introduced into a trachea of the patient and can be subjected to the breathing gas and which has an inflatable cuff and at least one lumen that is continuous from a distal end of the ventilator tube to a proximal end of the ventilator tube, and wherein an airway pressure is detected, the improvement comprising:

determining the tracheobronchial airway pressure by one of continuous and intermittent detection and evaluation of an intra-cuff pressure prevailing in the cuff of the tube inserted into the trachea, and controlling the flow of the breathing gas in the ventilator as a function of a detected intra-cuff pressure, measuring an esophageal balloon pressure in the balloon of the gastric probe introduced into the esophagus and transmitting second measured values from the balloon to one of the ventilator and a control device for the ventilator, and measuring values obtained by the esophageal balloon pressure and using the values to ascertain a respiratory work done by the patient, and from breathing strokes pressure-supported by the ventilator of respiratory cycles of fixed duration determining cyclical breathing work diagrams and displaying them on a monitor as one of loops and areas.