Vision prosthesis

• US 7,041,133 B1
• Filed: 07/25/2003
• Issued: 05/09/2006
• Est. Priority Date: 07/20/2001
• Status: Expired due to Term

• Current Assignee: Massachusetts Eye And Ear Infirmary (Foundation of The Massachusetts Eye and EAR Infirmary Incorporated)
• Original Assignee: Massachusetts Eye And Ear Infirmary (Foundation of The Massachusetts Eye and EAR Infirmary Incorporated)
• Inventors: Azar, Dimitri
• Primary Examiner(s): McDermott, Corrine
• Assistant Examiner(s): Matthews, William H
• Application Number:
  US10/627,943
• Time in Patent Office: 1,019 Days
• Field of Search: 623/4.1, 623/5.11, 623/6.22, 623/6.34, 623/6.37, 396 75- 77, 396/89, 351/41, 351/57, 351/158, 351/168
• US Class Current: 623/6.22
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61B 5/6821 Eye
• CPC Class Codes: A61F 2/145 Corneal inlays, onlays, or lenses for refractive correction
• CPC Class Codes: A61F 2/147 Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants
• CPC Class Codes: A61F 2/1602 Corrective lenses for use in addition to the natural lenses of the eyes or for pseudo-phakic eyes
• CPC Class Codes: A61F 2/1613 having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
• CPC Class Codes: A61F 2/1618 Multifocal lenses
• CPC Class Codes: A61F 2/1627 for changing index of refraction, e.g. by external means or by tilting
• CPC Class Codes: A61F 2/1629 for changing longitudinal position, i.e. along the visual axis when implanted
• CPC Class Codes: A61F 2/1635 for changing shape
• CPC Class Codes: A61F 2/1648 Multipart lenses
• CPC Class Codes: A61F 2002/1699 Additional features not otherwise provided for
• CPC Class Codes: A61F 2250/0001 Means for transferring electromagnetic energy to implants
• CPC Class Codes: A61F 2250/0002 for data transfer
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/08 Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception
• CPC Class Codes: G02B 3/14 of variable focal length

Abstract

A vision prosthesis includes a lens having an index of refraction that varies in response to a focusing stimulus. An actuator in communication with the lens provides the focusing stimulus on the basis of a range estimate from a rangefinder. A controller coupled to the rangefinder and to the actuator causes the actuator to generate a focusing stimulus on the basis of the range estimate.

Claims

1. An apparatus comprising:

an intraocular lens having an index of refraction that varies in response to a focusing stimulus;

an actuator in communication with said lens for providing said focusing stimulus;

a rangefinder for generating a range estimate indicative of a relative distance to an object-of-regard; and

a controller coupled to said rangefinder and to said actuator for causing said actuator to generate a focusing stimulus on the basis of said range estimate.

2. The apparatus of claim 1, wherein said lens is adapted for implantation at a location in an eye, said location being selected from the group consisting of:

the anterior chamber;

the posterior chamber;

the lens bag; and

the cornea.

3. The apparatus of claim 1, wherein said lens is adapted for implantation in an aphakic human patient.

4. The apparatus of claim 1, wherein said lens is adapted for implantation in a phakic human patient.

5. The apparatus of claim 1, wherein said lens is a foldable lens having a tendency to spring back into an unfolded state.

6. The apparatus of claim 1, wherein said lens comprises a chamber containing nematic liquid crystal.

7. The apparatus of claim 6, wherein said chamber comprises a first planar side and a second planar side opposed to said first planar side, said first and second planar sides being separated by a gap smaller than a separation between a lens bag in an eye and an iris in said eye.

8. The apparatus of claim 1, wherein said actuator comprises a variable voltage source.

9. The apparatus of claim 8, wherein said actuator further comprises an electrode coupled to said variable voltage source and to said lens for applying an electric field within said lens.

10. The apparatus of claim 1, wherein said actuator comprises a plurality of actuating elements coupled to different local regions of said lens for selectively varying said index of refraction at said different local regions of said lens.

11. The apparatus of claim 10, wherein each of said local regions of said lens has a local curvature.

12. The apparatus of claim 10, wherein said actuating elements comprise a plurality of electrodes disposed at different portions of said lens.

13. The apparatus of claim 1, wherein said rangefinder comprises an autofocus system.

14. The apparatus of claim 13, wherein said autofocus system comprises:

an infrared transmitter for illuminating an object with an infrared beam;

an infrared receiver for receiving a reflected beam from said object, and

a processor coupled to said infrared receiver for estimating a range to said object on the basis of said reflected beam.

15. The apparatus of claim 13, wherein said rangefinder further comprises a feedback loop coupled to said autofocus system.

16. The apparatus of claim 1, further comprising a manual focusing control for enabling a patient to fine tune focusing of said lens.

17. An apparatus comprising:

a intraocular lens having an index of refraction that varies in response to a focusing stimulus;

an actuator in communication with said lens for providing said focusing stimulus;

a rangefinder for generating a range estimate indicative of a relative distance to an object-of-regard, said rangefinder including a transducer for detecting a stimulus from an anatomic structure in an eye, said stimulus being indicative of a range to said object-of-regard; and

a controller coupled to said rangefinder and to said actuator for causing said actuator to generate a focusing stimulus on the basis of said range estimate.

18. The apparatus of claim 17, wherein said transducer comprises a pressure transducer for detecting contraction of a muscle.

19. The apparatus of claim 18, wherein said pressure transducer comprises a piezoelectric element that generates a voltage in response to contraction of said muscle.

20. An apparatus comprising:

an intraocular lens system having a focal length that varies in response to a focusing stimulus;

an actuator in communication with the lens system for providing the focusing stimulus;

a rangefinder for generating a range estimate indicative of a relative distance to an object-of-regard; and

a controller coupled to the rangefinder and to the actuator for causing the actuator to generate the focusing stimulus on the basis of the range estimate.

21. The apparatus of claim 20, wherein the lens system comprises an optically transmissive medium having an optical index that varies in response to the focusing stimulus.

22. The apparatus of claim 20, wherein the lens system comprises at least two lens elements that move relative to each other in response to the focusing stimulus.

23. The apparatus of claim 20, wherein the lens system comprises a lens element that moves in response to the focusing stimulus.

24. The apparatus of claim 20, wherein the lens system comprises an optically transmissive medium having a surface, at least a portion of which changes shape in response to the focusing stimulus.

25. The apparatus of claim 20, wherein the rangefinder comprises a transducer for receiving a signal indicative of the distance to the object-of-regard.

26. The apparatus of claim 25, wherein the transducer comprises a force transducer.

27. The apparatus of claim 26, wherein the force transducer is configured to be in mechanical communication with an intraocular structure.

28. The apparatus of claim 27, wherein the force transducer is configured to be in mechanical communication with an intraocular structure selected from the group consisting of a zonule, a ciliary muscle, a media rectus muscle, a lens bag, and an iris.

29. The apparatus of claim 27, wherein the rangefinder is configured to detect electrical activity associated with actuation of an intraocular structure.

30. The apparatus of claim 27, wherein the rangefinder comprises an auto focus system.