Kit for measuring analytes

• US 7,041,254 B2
• Filed: 04/23/2003
• Issued: 05/09/2006
• Est. Priority Date: 06/19/2001
• Status: Expired due to Term

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Lifescan Incorporated (Duv Holding Corporation)
• Inventors: Bennett, Gregory, Bird, Dennis, Hufford, William, Haviland, Alan
• Primary Examiner(s): GITOMER, RALPH J
• Application Number:
  US10/422,589
• Publication Number:
  US 20030203352A1
• Time in Patent Office: 1,112 Days
• Field of Search: 422/58, 422/56, 422/60, 435/4, 435/287.7, 435/970, 435/436, 435/975
• US Class Current: 422/404
• CPC Class Codes: G01N 33/558 using diffusion or migration of antigen or antibody immunochromatographic test strips G01N33/54387
• CPC Class Codes: G01N 33/66 involving blood sugars, e.g. galactose
• CPC Class Codes: Y10S 435/975 Kit
• CPC Class Codes: Y10T 436/144444 Glucose

Abstract

Devices, systems, methods and kits are provided for use in determining the concentration of chemical and biochemical components in aqueous fluids. The subject devices include test strips which define a longitudinal axis and include a distal edge configured for insertion into a measurement instrument and having an alignment notch formed in the distal edge for engagement with an alignment member of the measurement instrument. The alignment notch has opposing edges wherein at least a portion of the opposing edges is in substantially parallel relation to the longitudinal axis. In using the subject devices, the devices are inserted into a measurement instrument having an alignment pin. When operatively engaged with the alignment pin, the notch serves to maintain the device in a substantially motionless position. The invention is useful in a variety of applications, particularly in the determination of blood glucose concentrations.

Claims

1. A kit for measuring the concentration of at least one target analyte in a sample of biological fluid, said kit comprising:

(a) at least one test strip having top and bottom surfaces, comprising;

(i) a substantially obround-shaped aperture for receiving a volume of from about 5 μ

L to about 10 μ

L of said sample of biological fluid;

(ii) a hydrophilic pad affixed to one of said top or bottom surfaces and covering said substantially obround-shaped aperture; and

(iii) an alignment notch comprising opposing parallel edges; and

(b) a measurement instrument comprising an alignment pin configured for engagement with said alignment notch wherein said test strip is maintained in a substantially motionless position with respect to said alignment pin when said test strip is operatively engaged within said test strip holder.

2. The kit of claim 1 wherein said volume of said sample is about 5 μ

L.

3. The kit of claim 1 wherein said measurement instrument is a spectrometer.