Method of optical measurements for determining various parameters of the patient's blood
First Claim
1. A method for use in non-invasive measurements of chemical compositions of a patient'"'"'s blood, comprising:
- creating a state of blood flow cessation of the patient'"'"'s blood within a measurement region of the patient'"'"'s body and maintaining the blood-flow cessation state during a predetermined time period which is insufficient for irreversible changes to occur in the body, thereby affecting an erythrocytes'"'"' aggregation process in the measurement location defining a change in characteristics of the patient'"'"'s blood;
applying an external electromagnetic field to the measurement region within said predetermined time period, and obtaining measured data representative of the time dependence of a response of the blood in the measurement region to said external electromagnetic field, the measured time dependence including an initial time period of the response variation and an asymptotic time period of relatively slow changes of the response as compared to the initial time period; and
analyzing the measured data for determining one or more parameters of the patient'"'"'s blood, including extracting characteristics associated with the erythrocytes aggregation process during the state of the blood flow cessation.
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Abstract
A method for optical measurements of desired parameters of the patient'"'"'s blood is presented. A state of the blood flow cessation is provided within a measurement region and maintained during a predetermined time period. Measurement sessions are performed within this predetermined time period. Each measurement session includes at least two measurements with different wavelengths of incident light. Obtained measured data is representative of the time dependence of light response of the blood in the measurement region. The analyses of the measured data enables the determination of the desired blood parameters extracted from optical characteristics associated with the erythrocytes aggregation process during the state of the blood flow cessation.
166 Citations
31 Claims
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1. A method for use in non-invasive measurements of chemical compositions of a patient'"'"'s blood, comprising:
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creating a state of blood flow cessation of the patient'"'"'s blood within a measurement region of the patient'"'"'s body and maintaining the blood-flow cessation state during a predetermined time period which is insufficient for irreversible changes to occur in the body, thereby affecting an erythrocytes'"'"' aggregation process in the measurement location defining a change in characteristics of the patient'"'"'s blood; applying an external electromagnetic field to the measurement region within said predetermined time period, and obtaining measured data representative of the time dependence of a response of the blood in the measurement region to said external electromagnetic field, the measured time dependence including an initial time period of the response variation and an asymptotic time period of relatively slow changes of the response as compared to the initial time period; and analyzing the measured data for determining one or more parameters of the patient'"'"'s blood, including extracting characteristics associated with the erythrocytes aggregation process during the state of the blood flow cessation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
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30. A method of non-invasive optical measurements in a patient'"'"'s body, the method comprising:
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creating a state of blood flow cessation of the patient'"'"'s blood within a measurement region of the patient'"'"'s body and maintaining the blood-flow cessation state during a predetermined time period being insufficient for irreversible changes to occur in the body, thereby affecting an erythrocytes'"'"' aggregation process in the measurement location defining optical characteristics of blood; applying measurements to the measurement region within said predetermined time period, and obtaining measured data representative of the time dependence of a light response of the blood in the measurement region to incident light of one or more wavelengths, the measured time dependence including an initial time period of the light response variation and an asymptotic time period of relatively slow charges of the light response as compared to the initial time period; analyzing the measured data for determining one or more chemical compositions of the patient'"'"'s blood, extracted from optical characteristics associated with the erythrocytes aggregation process during the state of the blood flow cessation.
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31. An apparatus for non-invasive optical measurements of chemical compositions of the patient'"'"'s blood, the apparatus comprising:
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an occlusion assembly adapted for applying pressure to the patient'"'"'s body, so as to create a state of the blood flow cessation in a measurement region in the body for a predetermined time period; illumination/detection assembly for applying optical measurements with at least two different wavelengths of incident radiation to said measurement region during said predetermined period of time, and generating data representative of light response signals; and a control unit configured to be responsive to the generated data and preprogrammed for carrying out the following;
determining, from said generated data, measured data in the form of time variations of the light response signals;
utilizing optical characteristics associated with erythrocytes aggregation process during the state of the blood flow cessation to analyze the measured data from within a preset time interval of said predetermined period of time and determine one or more chemical compositions of the patient'"'"'s blood.
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Specification