Apparatus and method for outputting heart sounds

• US 7,052,466 B2
• Filed: 04/11/2001
• Issued: 05/30/2006
• Est. Priority Date: 04/11/2001
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Olive, Arthur L., Villalta, Don, Scheiner, Avram, Zhu, Qingsheng
• Primary Examiner(s): Pezzuto, Robert E.
• Assistant Examiner(s): DROESCH, KRISTEN L
• Application Number:
  US09/833,229
• Publication Number:
  US 20020151812A1
• Time in Patent Office: 1,875 Days
• Field of Search: 600/508, 600/509, 600/513, 600/528, 600586-587, 600/301, 600/523, 607/4, 607/9, 607 17- 20, 607/27, 607 30- 32, 607 59- 60, 607 1- 3, 128/120
• US Class Current: 600/528
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/1118 Determining activity level
• CPC Class Codes: A61B 5/283 Invasive
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/339 Displays specially adapted therefor
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 7/00 Instruments for auscultation
• CPC Class Codes: A61B 7/023 for introduction into the body, e.g. into the oesophagus oesophageal ECG probes A61B5/285
• CPC Class Codes: A61B 7/04 Electric stethoscopes microphones, acoustic transducers therefor H04R

Abstract

An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.

Claims

1. A method of outputting heart sounds using an implanted system, comprising:

generating first data representative of heart sounds in the implanted system using ensemble averaging;

receiving the first data from the implanted system;

generating control signals using the first data;

generating timing comparison control signals indicative of a timing of the control signals; and

applying the control signals and the timing comparison control signals to an output device to cause the output device to generate outputs which are representative of the heart sounds and timing information related to the heart sounds.

2. The system of claim 1, wherein the averaging includes sequentially averaging a number of completed cardiac cycles over a period of time.

3. The system of claim 1, wherein the averaging includes averaging a number of completed cardiac cycles while a patient condition is present.

4. The method of claim 1, further comprising receiving surface ECG data, wherein generating the control signals also includes using the surface ECG data, and applying the control signals to the output device also causes the output device to generate surface ECG outputs which are representative of the surface ECG.

5. The method of claim 4, further comprising outputting relative timing information between the heart sounds and surface ECG events on the output device.

6. The method of claim 1, further comprising receiving second data representative of first cardiac electrical signals from the implanted system wherein generating the control signals includes using the second data, and applying the control signals to the output device causes the output device to generate outputs which are representative of the heart sounds and the first cardiac electrical signals.

7. The method of claim 6, further comprising outputting relative timing information between the heart sounds and the first cardiac electrical signals on the output device.

8. The method of claim 6, further comprising receiving third data representative of second cardiac electrical signals from the implanted system, wherein generating the control signals includes using the third data, and applying the control signals to the output device causes the output device to generate outputs which are representative of the heart sounds, and the first and second cardiac electrical signals.

9. The method of claim 8, further comprising outputting relative timing information between the heart sounds, the first cardiac electrical signals, and the second cardiac electrical signals on the output device.

10. A method of outputting heart sounds using an implanted system, comprising:

detecting heart sounds using a plurality of first implanted sensors;

generating first data representative of the heart sounds for visual display of the heart sounds using band-pass filtering and ensemble averaging;

transmitting the first data representative of the heart sounds to an external system; and

generating second data representative of the heart sounds for machine detection of the heart sounds using band-pass filtering, rectification, low-pass filtering, and ensemble averaging.

11. The method of claim 10, further comprising detecting first cardiac electrical signals using a second implanted sensor, transmitting data representative of the first cardiac electrical signals to the external system, and simultaneously displaying the data representative of the heart sounds and the data representative of the first cardiac electrical signals.

12. The method of claim 11, further comprising detecting second cardiac electrical signals using a third implanted sensor, transmitting data representative of the second cardiac electrical signals to the external system, and simultaneously displaying the data representative of the heart sounds, the data representative of the first cardiac electrical signals, and the data representative of the second cardiac electrical signals.

13. An implantable system, comprising:

a plurality of sensors configured to detect heart sounds and to generate a plurality of sensed signals representative of the heart sounds;

an interface circuit for communicating with an external system; and

a control circuit, coupled to the plurality of sensors and the interface circuit, configured to receive the plurality of sensed signals, to generate data representative of the heart sounds, and to transmit the data to the external system via the interface circuit,

wherein the control circuit provides for a first processing path including a first band-pass filter, a rectifier, a low-pass filter, and a first ensemble averager to process the plurality of sensed signals for machine detection of the heart sounds and a second processing path including a second band-pass filter and a second ensemble averager to process the plurality of sensed signals for visual display of the heart sounds,

wherein the plurality of sensors, interface circuit and control circuit are implantable.

14. The system of claim 13, wherein the plurality of sensors include an accelerometer.

15. The system of claim 13, further comprising an implantable housing for the control circuit, wherein at least one of the plurality of sensors is located internal to the implantable housing.

16. The system of claim 13, further comprising an implantable housing for the control circuit, wherein at least one of the plurality of sensors is located external to the implantable housing.

17. The system of claim 13, wherein the interface circuit is configured to communicate with the external system using radio-frequency (RF) signals.

18. The system of claim 13, wherein the interface circuit is configured to communicate with the external system using optical signals.

19. The system of claim 13, wherein the data transmitted by the control circuit to the external system includes raw data determined by digitizing the sensed signals.

20. The system of claim 13, wherein the data transmitted by the control circuit to the external system includes processed data from processing the sensed signals.

21. The system of claim 13, wherein the control circuit further includes a systole detector coupled to the ensemble averager wherein detection of systole triggers the ensemble averager.

22. The system of claim 13, wherein the control circuit further includes a band pass filter coupled to the sensor and ensemble averager, wherein the output of the band pass filter is applied to the ensemble averager.

23. The system of claim 13, wherein the control circuit further includes:

a band pass filter to receive signals from the sensor;

a rectifier coupled to the band pass filter; and

a low pass filter coupled to the rectifier and the ensemble averager.

24. A system, comprising:

an implantable device including;

a first sensor for detecting heart sounds and for generating first sensed signals representative of the heart sounds;

a second sensor for detecting cardiac electrical signals and for generating second sensed signals representative of the cardiac electrical signals;

a first interface circuit; and

a first control circuit that includes a bandpass filter and an ensemble averager, coupled to the sensors and the interface circuit, configured to receive the first and second sensed signals, to generate first data representative of the heart sounds from the first sensed signals by filtering and averaging the signals, to generate second data representative of the cardiac electrical signals from the second sensed signals, and to transmit the first data and the second data via the first interface circuit; and

an external device communicatively coupled to the implantable device, the external device including;

a second interface circuit;

an output device including a display configured to simultaneously display multiple signals; and

a second control circuit, coupled to the second interface circuit and the output device, configured to receive the first data and the second data via the interface circuit, detect predetermined type heart sounds from the first data and predetermined type electrical cardiac events from the second data, calculate at least one timing difference between an electrical cardiac event of the predetermined type electrical cardiac events and a heart sound of the predetermined type heart sounds, and generate control signals causing the output device to simultaneously output at least the first sensed signals, the second sensed signals, and the at least one timing difference.

25. The system of claim 24, wherein the first sensor includes an accelerometer.

26. The system of claim 24, wherein the implantable device comprises an implantable housing for the control circuit, wherein the first sensor is internal to the implantable housing.

27. The system of claim 24, wherein the implantable device comprises an implantable housing for the control circuit, wherein the first sensor is external to the implantable housing.

28. The system of claim 24, wherein the second sensor includes an EGM sensing electrode and the second sensed signals are representative of EGM electrical signals.

29. The system of claim 24, wherein the second sensor includes an atrial sensing electrode and the second sensed signals are representative of atrial electrical signals.

30. The system of claim 24, wherein the second sensor includes a ventricular sensing electrode and the second sensed signals are representative of ventricular electrical signals.

31. The system of claim 24, wherein the second sensor is adapted to be disposed in the right side of the heart.

32. The system of claim 24, wherein the second sensor is adapted to be disposed in the left side of the heart.

33. The system of claim 24, wherein the first data transmitted by the control circuit to the external system includes raw data determined by digitizing the first sensed signals.

34. The system of claim 24, wherein the first data transmitted by the control circuit to the external system includes processed data from processing the first sensed signals.