Analyte concentration detection devices and methods
First Claim
1. A device for use in conducting an assay to determine the concentration of an analyte in a sample of bodily fluid, the device comprising:
- a sample collection chamber having a bottom with at least one opening;
an assay pad in communication with the at least one opening of the chamber, the assay pad comprising a reagent adapted to produce a chemical reaction when exposed to the analyte, the chemical reaction producing a color change in the assay pad; and
a linear array of CMOS optical detectors disposed relative to the assay pad so as to detect the color change, wherein the chamber defines a length, and the linear array has a plurality of CMOS sensors that define a length of the array that is commensurate to the length of the chamber.
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Accused Products
Abstract
Arrangements for the detection of the presence and/or concentration of an analyte in a sample of bodily fluid include diffuse transmission, diffuse reflection and edge or waveguide illumination arrangements. A vertical flow assay arrangement and/or technique is also disclosed, and includes a detection component that can be in the form of an array of optical detection elements. A number of assay pad constructions are described which may include at least one or more of the following components: a prefilter component, a reflective component, a membrane component, a reagent component, a mesh component, and a component to prevent lateral spreading.
189 Citations
23 Claims
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1. A device for use in conducting an assay to determine the concentration of an analyte in a sample of bodily fluid, the device comprising:
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a sample collection chamber having a bottom with at least one opening;
an assay pad in communication with the at least one opening of the chamber, the assay pad comprising a reagent adapted to produce a chemical reaction when exposed to the analyte, the chemical reaction producing a color change in the assay pad; and
a linear array of CMOS optical detectors disposed relative to the assay pad so as to detect the color change, wherein the chamber defines a length, and the linear array has a plurality of CMOS sensors that define a length of the array that is commensurate to the length of the chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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Specification