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Methods of electrotransport drug delivery

  • US 7,054,683 B2
  • Filed: 08/29/2005
  • Issued: 05/30/2006
  • Est. Priority Date: 06/28/2002
  • Status: Active Grant
First Claim
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1. A method of varying the delivery rate of a drug comprising:

  • providing a plurality electrotransport delivery reservoirs, each reservoir adapted to be placed in drug-transmitting contact with a subject body surface for delivering the drug through the body surface by means of an electrotransport current (i) applied to the reservoir via a reservoir-contacting electrode, the reservoir being permeable to electrically assisted flux of the drug, each of the reservoirs containing the same drug and the geometry of each of the reservoirs being defined by at least three parameters including average cross-sectional area ARES, average thickness, and body surface contact area ABODY;

    arranging an electronic controller including an electronic circuit adapted to control the electrotransport current applied to the reservoirs so that the controller can be connected to each of the plurality of reservoirs; and

    varying at least one of the parameters for one of the plurality of reservoirs so that the varied parameter is different than the same parameter for another of the plurality of reservoirs such that the delivery rate from one of the plurality of reservoirs is different than the delivery rate of another of the plurality of reservoirs.

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