AC methods for the detection of nucleic acids
First Claim
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1. A composition for detecting a target nucleic acid, comprising:
- a) a first and second electrode, wherein said first electrode comprises a monolayer comprising a spacer, wherein said spacer is covalently attached to a single stranded nucleic acid; and
b) an AC/DC voltage source electrically connected to said first and second electrodes.
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Abstract
The invention relates to nucleic acids covalently coupled to electrodes via conductive oligomers. More particularly, the invention is directed to the site-selective modification of nucleic acids with electron transfer moieties and electrodes to produce a new class of biomaterials, and to methods of making and using them.
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Citations
13 Claims
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1. A composition for detecting a target nucleic acid, comprising:
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a) a first and second electrode, wherein said first electrode comprises a monolayer comprising a spacer, wherein said spacer is covalently attached to a single stranded nucleic acid; and b) an AC/DC voltage source electrically connected to said first and second electrodes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification